{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T21:55:21Z","timestamp":1790373321633,"version":"4.1.0"},"reference-count":35,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Open Heart"],"accepted":{"date-parts":[[2017,3,7]]},"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Success rates of catheter ablation (CA) of persistent atrial fibrillation (AF) are very variable. Identifying patients in whom sinus rhythm maintenance cannot be achieved after CA is a critical issue.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>2D speckle-tracking echocardiography was performed before the first CA procedure in consecutive patients with persistent AF. Left atrial (LA) strain was correlated with recurrence of atrial arrhythmias during the follow-up period of 15 months after one CA procedure with or without antiarrhythmic drugs (primary endpoint). In a secondary analysis, recurrences after two CA procedures were analysed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>102 patients were included. Patients with recurrence of atrial arrhythmias after one CA procedure (n=55) had significantly lower LA strain than those without recurrence (LA strain 9.7\u00b12.4% vs 16.2\u00b13.0%; p&lt;0.001). Recurrence rate was significantly higher in patients with LA strain &lt;10% than in those with LA strain between 10% and 14.5%\u2009and &gt;14.5% (97.7%, 42.1% and 10.3%, respectively; p&lt;0.001). In Cox regression analysis including age, comorbidities, left ventricular dysfunction and LA enlargement, low LA strain (&lt;10%) was the strongest factor associated with recurrence of AF (HR 6.4 (2.4\u201316.9), p&lt;0.001). Even after inclusion of a second CA procedure, LA strain &lt;10% maintained a high predictive value for recurrence of atrial arrhythmias (86.4% (95% CI 73.3% to 93.6%)).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In patients with persistent AF, LA strain imaging could be very useful to select those patients who have a high risk of not benefiting from CA.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/openhrt-2016-000572","type":"journal-article","created":{"date-parts":[[2017,4,28]],"date-time":"2017-04-28T20:10:43Z","timestamp":1493410243000},"page":"e000572","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":53,"title":["Left atrial strain predicts recurrence of atrial arrhythmias after catheter ablation of persistent atrial fibrillation"],"prefix":"10.1136","volume":"4","author":[{"given":"Abdul 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