{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T09:12:14Z","timestamp":1771233134895,"version":"3.50.1"},"reference-count":22,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Open Heart"],"accepted":{"date-parts":[[2019,7,4]]},"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To validate the Intra-aortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) score in patients with cardiogenic shock after ST elevation myocardial infarction (STEMI) treated with pharmacoinvasive strategy (PhIS) and to analyse the influence of ischaemia time on different risk strata.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We analysed 2143 patients with STEMI who underwent reperfusion with tenecteplase in primary health services between May 2010 and April 2017 and were transferred to a tertiary hospital for cardiac catheterisation and continuity of care. Those who evolved to cardiogenic shock were scored as low (0\u20132), moderate (3\u20134) or high (5\u20139) risk of death in 30 days and pairwise-log-rank test was used to compare strata. Time intervals between symptoms onset and lytic (pain-to-needle) and fibrinolytic-catheterisation were also compared.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Cardiogenic shock occurred in 212 (9.9%) individuals. The 30-day mortality using the IABP-SHOCK II score was 26.6% for low-risk (n=94), 53.2% for moderate-risk (n=62) and 76% for high-risk (n=25) analysed patients (p&lt;0.001). Validation of the score showed good discrimination for death, area under the curve of 0.73 (CI: 0.66 to 0.81;\u2009p&lt;0.001). The median intervals of pain-to-needle and fibrinolytic-catheterisation showed no association with the group stratification (220 vs 251 vs 200\u2009min; p=0.22\u2009and 390 vs 435 vs 315\u2009min; p=0.18, respectively).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>In patients with cardiogenic shock after STEMI treated with PhIS, risk stratification using IABP-SHOCK II score was adequate. There was no influence of pain-to-needle and fibrinolytic-catheterisation times on the ability to the score model stratification.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/openhrt-2019-001069","type":"journal-article","created":{"date-parts":[[2019,7,30]],"date-time":"2019-07-30T05:29:03Z","timestamp":1564464543000},"page":"e001069","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Cardiogenic shock after ST elevation myocardial infarction and IABP-SHOCK II risk score validation in a cohort treated with pharmacoinvasive strategy"],"prefix":"10.1136","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0488-0538","authenticated-orcid":false,"given":"Pedro Ivo M","family":"Moraes","sequence":"first","affiliation":[{"name":"Discipline of Cardiology - Department of Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Rodrigues","family":"Alves","sequence":"additional","affiliation":[{"name":"Discipline of Cardiology - Department of Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Tulio","family":"Souza","sequence":"additional","affiliation":[{"name":"Discipline of Cardiology - Department of Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzi Emiko","family":"Kawakami","sequence":"additional","affiliation":[{"name":"Discipline of Cardiology - Department of Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iran","family":"Goncalves Jr","sequence":"additional","affiliation":[{"name":"Discipline of Cardiology - Department of Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriano Henrique Pereira","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Discipline of Cardiology - Department of Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Celio","family":"Moreno","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital do Servidor P\u00fablico Municipal, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriano Mendes","family":"Caixeta","sequence":"additional","affiliation":[{"name":"Discipline of Cardiology - Department of Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil"},{"name":"Department of Cardiology, Hospital Israelita Albert Einstein, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Carlos","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Discipline of Cardiology - Department of Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,7,29]]},"reference":[{"key":"2025081710591062000_6.2.e001069.1","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.113.000590","article-title":"Trends in incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction in the United States","volume":"3","author":"Kolte","year":"2014","journal-title":"J Am Heart Assoc"},{"key":"2025081710591062000_6.2.e001069.2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.814947"},{"key":"2025081710591062000_6.2.e001069.3","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs264"},{"key":"2025081710591062000_6.2.e001069.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2009.08.005"},{"key":"2025081710591062000_6.2.e001069.5","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1136\/hrt.2003.021691","article-title":"Predictors of outcome after percutaneous treatment for cardiogenic shock","volume":"91","author":"Sutton","year":"2005","journal-title":"Heart"},{"key":"2025081710591062000_6.2.e001069.6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.amjcard.2005.02.040","article-title":"Mortality after emergent percutaneous coronary intervention in cardiogenic shock secondary to acute myocardial infarction and usefulness of a mortality prediction model","volume":"96","author":"Klein","year":"2005","journal-title":"Am J Cardiol"},{"key":"2025081710591062000_6.2.e001069.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.12.033"},{"key":"2025081710591062000_6.2.e001069.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.06.024"},{"key":"2025081710591062000_6.2.e001069.9","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV10STA12"},{"key":"2025081710591062000_6.2.e001069.10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1301092"},{"key":"2025081710591062000_6.2.e001069.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60268-8"},{"key":"2025081710591062000_6.2.e001069.12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.762765"},{"key":"2025081710591062000_6.2.e001069.13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808276"},{"key":"2025081710591062000_6.2.e001069.14","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl461"},{"key":"2025081710591062000_6.2.e001069.15","unstructured":"Elguindy AM . Lessons from the trials stream and FAST-MI \u2013 Pharmacoinvasive therapy: a continued role for fibrinolysis in the primary PCI era."},{"key":"2025081710591062000_6.2.e001069.16","doi-asserted-by":"publisher","DOI":"10.1590\/S0066-782X2012005000100"},{"key":"2025081710591062000_6.2.e001069.17","first-page":"1173","article-title":"St segment elevation myocardial infarction (STEMI) network sustains low hospital mortality throughout the years in an emerging country location","volume":"35","author":"Ferreira","year":"2014","journal-title":"Eur Heart J"},{"key":"2025081710591062000_6.2.e001069.18","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/eurheartj\/ehx393","article-title":"2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation","volume":"39","author":"Ibanez","year":"2018","journal-title":"Eur Heart J"},{"key":"2025081710591062000_6.2.e001069.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.02.027"},{"key":"2025081710591062000_6.2.e001069.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.04.084"},{"key":"2025081710591062000_6.2.e001069.21","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.110.958199"},{"key":"2025081710591062000_6.2.e001069.22","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)02514-7"}],"container-title":["Open Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/openhrt-2019-001069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,17]],"date-time":"2025-08-17T17:59:20Z","timestamp":1755453560000},"score":1,"resource":{"primary":{"URL":"https:\/\/openheart.bmj.com\/lookup\/doi\/10.1136\/openhrt-2019-001069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":22,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,7,29]]},"published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1136\/openhrt-2019-001069"],"URL":"https:\/\/doi.org\/10.1136\/openhrt-2019-001069","relation":{},"ISSN":["2053-3624"],"issn-type":[{"value":"2053-3624","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}