{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T08:52:00Z","timestamp":1792745520178,"version":"4.5.0"},"reference-count":29,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T00:00:00Z","timestamp":1587427200000},"content-version":"unspecified","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Open Heart"],"accepted":{"date-parts":[[2020,2,4]]},"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Tricuspid regurgitation (TR) severity has known adverse implications, its impact on patients undergoing non-cardiac surgery (NCS) remains unclear. We sought to determine the impact of TR on patient outcomes after NCS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a retrospective cohort study in patients undergoing NCS. Outcomes in patients with moderate or severe TR were compared with no\/trivial TR after adjusting for baseline characteristics and revised cardiac risk index (RCRI). The primary outcome was defined as 30-day mortality and heart failure (HF), while the secondary outcome was long-term mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 7064 patients included, 312 and 80 patients had moderate and severe TR, respectively. Thirty-day mortality was higher in moderate TR (adjusted OR 2.44, 95% CI 1.25 to 4.76) and severe TR (OR 2.85, 95% CI 1.04 to 7.79) compared with no\/trivial TR. There was no difference in 30-day HF in patients with moderate TR (OR 1.48, 95% CI 0.90 to 2.44) or severe TR (OR 1.42, 95% CI 0.60 to 3.39). The adjusted HR for long-term mortality in moderate TR was 1.55 (95% CI 1.31 to 1.82) and 1.87 (95% CI 1.40 to 2.50) for severe TR compared with no\/trivial TR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Increasing TR severity has higher postoperative 30-day mortality in patients undergoing NCS, independent of RCRI risk factors, ejection fraction or mitral regurgitation. Severity of TR should be considered in risk stratification for patients undergoing NCS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/openhrt-2019-001183","type":"journal-article","created":{"date-parts":[[2020,4,22]],"date-time":"2020-04-22T05:45:20Z","timestamp":1587534320000},"page":"e001183","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Impact of tricuspid regurgitation on postoperative outcomes after non-cardiac surgeries"],"prefix":"10.1136","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1037-6960","authenticated-orcid":false,"given":"Parth","family":"Parikh","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kinjal","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambreen","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Anumandla","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yash","family":"Jobanputra","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venu","family":"Menon","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Griffin","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E Murat","family":"Tuzcu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir","family":"Kapadia","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,4,21]]},"reference":[{"key":"2025081710210851000_7.1.e001183.1","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1097\/00132586-197810000-00051","article-title":"Multifactorial index of cardiac risk in noncardiac surgical procedures","volume":"22","author":"Goldman","year":"1978","journal-title":"Surv Anesthesiol"},{"key":"2025081710210851000_7.1.e001183.2","first-page":"193","article-title":"Impact of aortic stenosis on postoperative outcomes after noncardiac surgeries","volume":"6","author":"Agarwal","year":"2013","journal-title":"Circulation"},{"key":"2025081710210851000_7.1.e001183.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2012.12.005"},{"key":"2025081710210851000_7.1.e001183.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.07.944"},{"key":"2025081710210851000_7.1.e001183.5","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2014-307252"},{"key":"2025081710210851000_7.1.e001183.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2014.08.008"},{"key":"2025081710210851000_7.1.e001183.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.09.036"},{"key":"2025081710210851000_7.1.e001183.8","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1161\/CIRCULATIONAHA.118.038946","article-title":"Excess mortality associated with functional tricuspid regurgitation complicating heart failure with reduced ejection fraction","volume":"140","author":"Benfari","year":"2019","journal-title":"Circulation"},{"key":"2025081710210851000_7.1.e001183.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2006.08.049"},{"key":"2025081710210851000_7.1.e001183.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.09.069"},{"key":"2025081710210851000_7.1.e001183.11","unstructured":"Taramasso M , Benfari G , van der Bijl P , et al . 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