{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:08:49Z","timestamp":1791839329293,"version":"4.3.4"},"reference-count":39,"publisher":"BMJ","issue":"2","license":[{"start":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T00:00:00Z","timestamp":1657497600000},"content-version":"unspecified","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012190","name":"Ministry of Science and Higher Education of the Russian Federation","doi-asserted-by":"publisher","award":["The study was supported by the Ministry of Science"],"award-info":[{"award-number":["The study was supported by the Ministry of Science"]}],"id":[{"id":"10.13039\/501100012190","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Open Heart"],"accepted":{"date-parts":[[2022,5,25]]},"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Electrical muscle stimulation (EMS) is being evaluated as a possible alternative to exercise training to improve functional capacity in severely deconditioned patients with heart failure (HF). However, there is insufficient data on delayed effects of EMS starting early after decompensation. The aim of this study was to determine the impact of a short inpatient EMS intervention in severely deconditioned patients with HF on functional capacity and quality of life (QoL) over a follow-up period of 1\u2009month.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This is a prospective randomised sham-controlled pilot study. 45 patients hospitalised for decompensated systolic HF (58% men, mean age 66.4\u00b110.2 years) were randomised to EMS (n=22) or sham stimulation (n=23) of lower limbs starting within 3\u2009days after admission. The intervention included 7\u201310 sessions lasting from 30 to 90\u2009min. The 6-minute walking test distance (6-MWTD), Duke Activity Status Index (DASI) and Minnesota Living with Heart Failure Questionnaire (MLHFQ) were evaluated at baseline, discharge and after 1\u2009month.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>All patients completed the programme with good EMS tolerance. 37 patients were included in the final analysis. At discharge, 6-MWTD improved from 206,1\u00b161,3\u2009to 299.5\u00b191\u2009m, DASI from 12.1\u00b15.6\u2009to 18.3\u00b17.2 and MLHFQ from 55.6\u00b18.5\u2009to 34.2\u00b19 with EMS compared with smaller improvements in the sham group (p&lt;0.05 for all). One month after discharge, improvements in the EMS group remained significant for MLHFQ (p=0.004) and DASI (p=0.042) and statistically non-significant for 6-MWTD compared with the sham group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Short-term in-hospital EMS leads to improvements in functional capacity and QoL in selected patients early after HF decompensation that are retained over 1\u2009month after discharge and therefore may serve as initial intervention to improve physical capacity or as a bridge to further conventional exercise training. Larger studies are required to evaluate individual responses to an early initiation of EMS in decompensated HF as well as long-term effects.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/openhrt-2022-001965","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T11:45:51Z","timestamp":1657539951000},"page":"e001965","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["In-hospital electrical muscle stimulation for patients early after heart failure decompensation: results from a prospective randomised controlled pilot trial"],"prefix":"10.1136","volume":"9","author":[{"given":"Maria","family":"Poltavskaya","sequence":"first","affiliation":[{"name":"Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Sviridenko","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilya","family":"Giverts","sequence":"additional","affiliation":[{"name":"Rehabilitation, City Clinical Hospital #1, Moscow, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Patchenskaya","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inesa","family":"Kozlovskaya","sequence":"additional","affiliation":[{"name":"Sensory-Motor Physiology and Countermeasures, Institute of Biomedical Problems RAS, Moscow, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Tomilovskaya","sequence":"additional","affiliation":[{"name":"Sensory-Motor Physiology and Countermeasures, Institute of Biomedical Problems RAS, Moscow, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabil Orkhan","family":"Veliyev","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Andreev","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abram","family":"Syrkin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8025-7433","authenticated-orcid":false,"given":"Hugo","family":"Saner","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Functional and Ultrasound Diagnostics of N.V. Sklifosovsky Institute for Clinical Medicine, I.M.Sechenov First Moscow State Medical University, Moscow, Russian Federation"},{"name":"ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,7,11]]},"reference":[{"key":"2025081710534235000_9.2.e001965.1","article-title":"Esc scientific document group, 2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of cardiology (ESC) with the special contribution of the heart failure association (HFA) of the ESC","volume":"42","author":"McDonagh","year":"21  2021","journal-title":"European Heart 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