{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T08:41:04Z","timestamp":1773304864392,"version":"3.50.1"},"reference-count":11,"publisher":"BMJ","issue":"2","license":[{"start":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T00:00:00Z","timestamp":1666742400000},"content-version":"unspecified","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Fonds Scientifique Cardiovasculaire, Fribourg"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Open Heart"],"accepted":{"date-parts":[[2022,10,3]]},"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>Percutaneous coronary interventions require an arterial approach and administration of antithrombotic drugs. This may lead to bleeding complications. The aim of this study was to test whether \u201cThe Secret\u201d \u2013 a pagan prayer \u2013 is effective in reducing post-interventional bleeding.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>Randomised controlled trial.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>Monocentric, tertiary care centre.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Participants<\/jats:title>\n                  <jats:p>From January to July 2022, 200 patients (aged &gt;18 years) undergoing elective coronary angiography were included in the study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Intervention<\/jats:title>\n                  <jats:p>The intervention group received \u201cThe Secret<jats:italic>\u201d<\/jats:italic> in addition to the normal procedure. The control group was treated according to standard practice.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Main outcome measures<\/jats:title>\n                  <jats:p>The primary outcome was the rate of in-hospital bleeding according to the Bleeding Academic Research Consortium (BARC) consensus definition.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The rate of bleeding was similar in both groups (\u201cThe Secret\u201d group vs control group) with 16% versus 14% (p=0.69) of BARC 1, 12% versus 13% (p=0.81) of BARC 2, and 0% versus 0% of BARC 3 and 5 (p=1.00). Most (76%) of the participants believed that \u201cThe Secret<jats:italic>\u201d<\/jats:italic> would be efficient in preventing bleeding.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This study demonstrates no effect on bleeding after percutaneous coronary procedures. A large majority of our study population believe that \u201cThe Secret<jats:italic>\u201d<\/jats:italic> can have a positive effect on their hospital care.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/openhrt-2022-002134","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T20:10:43Z","timestamp":1671567043000},"page":"e002134","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Is the folk medicine known as \u201cThe Secret\u201d efficient in reducing bleeding after percutaneous coronary procedures?: a double-blinded, randomised trial"],"prefix":"10.1136","volume":"9","author":[{"given":"Charlie","family":"Ferry","sequence":"first","affiliation":[{"name":"Cardiology, University of Fribourg, Fribourg, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serban","family":"Puricel","sequence":"additional","affiliation":[{"name":"Cardiology, University of Fribourg, Fribourg, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja","family":"Lehmann","sequence":"additional","affiliation":[{"name":"Cardiology, University of Fribourg, Fribourg, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kit","family":"Rickard","sequence":"additional","affiliation":[{"name":"Economics, United Nations Unversity (UNU-WIDER), Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Meier","sequence":"additional","affiliation":[{"name":"Cardiology, University of Fribourg, Fribourg, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Togni","sequence":"additional","affiliation":[{"name":"Cardiology, University of Fribourg, Fribourg, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arroyo","family":"Diego","sequence":"additional","affiliation":[{"name":"Cardiology, University of Fribourg, Fribourg, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1221-2978","authenticated-orcid":false,"given":"St\u00e9phane","family":"Cook","sequence":"additional","affiliation":[{"name":"Cardiology, University of Fribourg, Fribourg, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,12,20]]},"reference":[{"key":"2025081611572107000_9.2.e002134.1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.319.7211.693"},{"key":"2025081611572107000_9.2.e002134.2","first-page":"227","article-title":"Acceptation of folk medicine and its \"secrets\" in a Swiss burn centre","volume":"32","author":"Kasser","year":"2019","journal-title":"Ann Burns Fire Disasters"},{"key":"2025081611572107000_9.2.e002134.3","unstructured":"Magali J . Chapter 1. In: Nouveau guide des gu\u00e9risseurs de Suisse romande. 3rd edition. Switzerland: Favre, 2019."},{"key":"2025081611572107000_9.2.e002134.4","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.3390\/jcm9051426","article-title":"Bleeding severity in percutaneous coronary intervention (PCI) and its impact on short-term clinical outcomes","volume":"9","author":"Murali","year":"2020","journal-title":"J Clin Med"},{"key":"2025081611572107000_9.2.e002134.5","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.008551","article-title":"Reversing the \"risk-treatment paradox\" of bleeding in patients undergoing percutaneous coronary intervention: risk-concordant use of bleeding avoidance strategies Is associated with reduced bleeding and lower costs","volume":"7","author":"Amin","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"2025081611572107000_9.2.e002134.6","unstructured":"Delaloye G . Gu\u00e9risseur d\u2019\u00e2mes et de corps, th\u00e9rapeute en soins \u00e9nerg\u00e9tiques, faiseur de secrets, magn\u00e9tiseur, masseur d\u00e9tente et sant\u00e9, 2022. Available: http:\/\/www.gedelaloye.ch\/ [Accessed 25 Jul 2022]."},{"key":"2025081611572107000_9.2.e002134.7","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1161\/CIRCULATIONAHA.119.040167","article-title":"Defining high bleeding risk in patients undergoing percutaneous coronary intervention","volume":"140","author":"Urban","year":"2019","journal-title":"Circulation"},{"key":"2025081611572107000_9.2.e002134.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.03.070"},{"key":"2025081611572107000_9.2.e002134.9","unstructured":"Magner LN , Kim OJ . Chapter 6. In: A history of medicine. 3rd edition. Boca Raton: CRC Press, 2017."},{"key":"2025081611572107000_9.2.e002134.10","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1590\/s1677-5538.ibju.2020.s121","article-title":"Social media influence in the COVID-19 pandemic","volume":"46","author":"Gonz\u00e1lez-Padilla","year":"2020","journal-title":"Int Braz J Urol"},{"key":"2025081611572107000_9.2.e002134.11","unstructured":"Smil V . Beyond magical thinking: time to get real on climate change. Yale E360. Available: https:\/\/e360.yale.edu\/features\/beyond-magical-thinking-time-to-get-real-about-climate-change [Accessed 14 Sep 2022]."}],"container-title":["Open Heart"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/openhrt-2022-002134","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,16]],"date-time":"2025-08-16T18:57:29Z","timestamp":1755370649000},"score":1,"resource":{"primary":{"URL":"https:\/\/openheart.bmj.com\/lookup\/doi\/10.1136\/openhrt-2022-002134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,12,20]]},"published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1136\/openhrt-2022-002134"],"URL":"https:\/\/doi.org\/10.1136\/openhrt-2022-002134","relation":{},"ISSN":["2053-3624"],"issn-type":[{"value":"2053-3624","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}