{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T08:20:14Z","timestamp":1781338814851,"version":"3.54.1"},"reference-count":30,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T00:00:00Z","timestamp":1739750400000},"content-version":"unspecified","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Open Heart"],"accepted":{"date-parts":[[2024,7,25]]},"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardial infarction-related cardiogenic shock (AMI-CS). In this Dutch registry, we investigated MCS usage, associated patient characteristics and clinical outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This real-world, multicentre registry included CS patients undergoing percutaneous coronary intervention between 2017 and 2021 in 14 Dutch hospitals. The impact on clinical outcomes was analysed after 1:1 average propensity-score (aPS) matching.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>This AMI-CS registry included 2217 patients with a mean age of 66.4 (\u00b112.3) years and predominantly male (72.8%, n=1613). MCS was deployed in 516 patients (23.3%), of which the intra-aortic balloon pump was used most frequently (n=253, 49.0%). Impella was used in 94 patients (18.2%), extracorporeal membrane oxygenation in 68 patients (13.2%) and 95 patients (18.4%) received multiple devices. Patients receiving MCS were younger (64.2 vs 67.0, p&lt;0.01), presented with lower mean arterial pressures (74.7 vs 78.4\u2009mm Hg, p&lt;0.01), higher heart rates (88.3 vs 81.7 beats per minute, p&lt;0.01) and higher initial lactate levels (6.4 vs 5.4\u2009mmol\/L, p&lt;0.01). The percentage of resuscitated patients was comparable among MCS and non-MCS patients (38.6% vs 42.2%, p=0.17). The 30-day mortality rate was higher in MCS patients (55.0% vs 34.7%, p&lt;0.01). After aPS-matching (n=970), 30-day mortality remained higher for MCS patients (53.8% vs 44.7%, p&lt;0.01), with an associated OR of 1.44 (95%\u2009CI 1.12 to 1.85, p&lt;0.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Despite limited evidence, MCS was used in a fourth of all AMI-CS patients. MCS usage was associated with an increased 30-day mortality in this real-world setting, even after propensity-matching.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/openhrt-2024-002846","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T17:55:47Z","timestamp":1739814947000},"page":"e002846","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical use and impact of mechanical circulatory support for myocardial infarction-related cardiogenic shock in the Netherlands: a registry-based propensity-matched analysis"],"prefix":"10.1136","volume":"12","clinical-trial-number":[{"clinical-trial-number":"nct05168462","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2554-6352","authenticated-orcid":false,"given":"Margriet","family":"Bogerd","sequence":"first","affiliation":[{"name":"Cardiology, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander M","family":"Griffioen","sequence":"additional","affiliation":[{"name":"Cardiology, Radboud Universitair Medisch Centrum, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen J H","family":"Bunge","sequence":"additional","affiliation":[{"name":"Cardiology, Erasmus MC, Rotterdam, The Netherlands"},{"name":"Intensive Care, Erasmus MC, Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elma J","family":"Peters","sequence":"additional","affiliation":[{"name":"Cardiology, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanne","family":"Ten Berg","sequence":"additional","affiliation":[{"name":"Cardiology, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijke J C","family":"Timmermans","sequence":"additional","affiliation":[{"name":"Netherlands Heart Registration, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriaan O","family":"Kraaijeveld","sequence":"additional","affiliation":[{"name":"Cardiology, UMC, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Lipsic","sequence":"additional","affiliation":[{"name":"Cardiology, University Medical Centre, Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luuk C","family":"Otterspoor","sequence":"additional","affiliation":[{"name":"Cardiology, Catharina Hospital, Eindhoven, The Netherlands"},{"name":"Intensive Care, Catharina Hospital, Eindhoven, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabe","family":"Bleeker","sequence":"additional","affiliation":[{"name":"Cardiology, Haga Hospital, Den Haag, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 M","family":"Montero-Cabezas","sequence":"additional","affiliation":[{"name":"Cardiology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krischan D","family":"Sjauw","sequence":"additional","affiliation":[{"name":"Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martijn","family":"Meuwissen","sequence":"additional","affiliation":[{"name":"Cardiology, Amphia Hospital, Breda, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A","family":"Dubois","sequence":"additional","affiliation":[{"name":"Cardiology, Erasmus MC, Rotterdam, The Netherlands"},{"name":"Intensive Care, Erasmus MC, Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert-Jan M","family":"van 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