{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:33:31Z","timestamp":1787502811472,"version":"build-2736575974"},"reference-count":90,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"unspecified","delay-in-days":36,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009530","name":"Jawaharlal Institute Of Postgraduate Medical Education and Research","doi-asserted-by":"publisher","award":["JIP\/Res\/Intramural\/Phase-3\/2024-2025\/30"],"award-info":[{"award-number":["JIP\/Res\/Intramural\/Phase-3\/2024-2025\/30"]}],"id":[{"id":"10.13039\/501100009530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Open Heart"],"accepted":{"date-parts":[[2026,1,19]]},"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Ischaemic heart disease (IHD) remains a leading cause of morbidity and mortality worldwide and poses an increasing public health challenge in India. The rising incidence of myocardial infarction, especially among younger individuals, is concerning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To compare cardiovascular risk factors, clinical presentation, angiographic patterns and reperfusion characteristics between younger and older adults presenting with ST-segment elevation myocardial infarction (STEMI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A cross-sectional analytical study was conducted among 260 patients admitted to a tertiary care hospital in South India with a first episode of STEMI. Participants were selected using convenience sampling and included 65 younger adults (\u226445 years) and 195 older adults (&gt;45 years) in a 1:3 ratio. Data were obtained through structured interviews and review of the medical records. Continuous variables were analysed using the Independent Student\u2019s t-test or Mann-Whitney U test, while categorical variables were assessed using the \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      or Fisher\u2019s exact test. Univariate and multivariate logistic regression analyses were performed with results reported as ORs and adjusted ORs with 95% CIs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean age was 40.14\u00b115.79 years in the younger group and 60.84\u00b18.25 years in the older group. Younger patients had a significantly higher male predominance, greater alcohol consumption, positive family history of premature cardiovascular disease, shorter sleep duration and higher anxiety scores. In contrast, older adults have a significantly higher prevalence of hypertension and diabetes mellitus. Multiple logistic regression revealed an increase in average sleep duration was associated with a 0.57-unit increase in the log-odds of being aged &gt;45 years. On the contrary, the anxiety score was inversely associated with older adults (\u03b2=\u22120.10; AOR=0.90; 95%\u2009CI 0.82 to 0.99).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Younger patients with acute STEMI exhibited an increased burden of modifiable lifestyle and psychosocial risk factors, emphasising the need for age-specific preventive interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/openhrt-2025-003937","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T13:25:19Z","timestamp":1770384319000},"page":"e003937","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of risk factors, clinical profile, angiographic characteristics and reperfusion therapy among young patients (\u2264 45 years) with acute ST-elevation myocardial infarction in comparison to older patients at a tertiary care centre in South India"],"prefix":"10.1136","volume":"13","author":[{"given":"Moumita","family":"Das","sequence":"first","affiliation":[{"name":"Department of Medical Surgical Nursing, College of Nursing, Jawaharlal Institute of Postgraduate Medical Education, Puducherry, PY, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4248-1407","authenticated-orcid":false,"given":"Lakshmi","family":"Ramamoorthy","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Nursing, College of Nursing, Jawaharlal Institute of Postgraduate Medical Education, Puducherry, PY, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A Shaheer","family":"Ahamed","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Jawaharlal Institute of Postgraduate Medical Education, Puducherry, PY, 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