{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:15:15Z","timestamp":1761128115529},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"944","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,6,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Infliximab is a monoclonal antibody against tumour necrosis factor-alpha. Recent studies have shown that it is effective in treating patients with refractory Crohn\u2019s disease and in those with Crohn\u2019s fistulae. Though this drug is found to be safe in clinical trials, sporadic reports of serious complications have been recorded in the literature. The case of a patient who developed profuse genital warts after infliximab treatment is reported. The literature is reviewed and information is presented on side effects and complications as a result of infliximab therapy.<\/jats:p>","DOI":"10.1136\/pgmj.2003.009332","type":"journal-article","created":{"date-parts":[[2004,6,10]],"date-time":"2004-06-10T20:23:34Z","timestamp":1086899014000},"page":"358-359","source":"Crossref","is-referenced-by-count":21,"title":["Genital condylomata in a patient receiving infliximab for Crohn\u2019s disease"],"prefix":"10.1093","volume":"80","author":[{"given":"A","family":"Somasekar","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Royal Glamorgan Hospital , Llantrisant, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Alcolado","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Royal Glamorgan Hospital , Llantrisant, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2004,6,10]]},"reference":[{"key":"2023050810275821900_R1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0950-3528(98)90083-5","article-title":"Pathogenesis of Crohn\u2019s disease.","volume":"12","author":"Hodgson","year":"1998","journal-title":"Baillieres Clin Gastroenterol"},{"key":"2023050810275821900_R2","doi-asserted-by":"crossref","first-page":"429","DOI":"10.2165\/00002018-200023050-00006","article-title":"Comparative tolerability of treatments for inflammatory bowel disease.","volume":"23","author":"Stein","year":"2000","journal-title":"Drug Saf"},{"key":"2023050810275821900_R3","first-page":"519","article-title":"Infliximab (Remicade), a new biological treatment for Crohn\u2019s disease.","volume":"31","author":"D\u2019Haens","year":"1999","journal-title":"Ital J Gastroenterol Hepatol"},{"key":"2023050810275821900_R4","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1056\/NEJM199905063401804","article-title":"Infliximab for the treatment of fistulas in patients with Crohn\u2019s disease.","volume":"340","author":"Present","year":"1999","journal-title":"N Engl J Med"},{"key":"2023050810275821900_R5","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1136\/gut.50.2.206","article-title":"Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn\u2019s disease.","volume":"50","author":"ten Hove","year":"2002","journal-title":"Gut"},{"key":"2023050810275821900_R6","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1053\/gast.2001.28702","article-title":"Infliximab induces apoptosis in monocytes from patients with chronic active Crohn\u2019s disease by using a caspase-dependent pathway.","volume":"121","author":"Lugering","year":"2001","journal-title":"Gastroenterology"},{"key":"2023050810275821900_R7","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1046\/j.1365-2036.2001.00956.x","article-title":"Infliximab induces potent anti-inflammatory and local immunomodulatory activity but no systemic immune suppression in patients with Crohn\u2019s disease.","volume":"15","author":"Cornillie","year":"2001","journal-title":"Aliment Pharmacol Ther"},{"issue":"suppl 4","key":"2023050810275821900_R8","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1046\/j.1365-2036.1999.00027.x","article-title":"Review article: safety of infliximab in clinical trials.","volume":"13","author":"Hanauer","year":"1999","journal-title":"Aliment Pharmacol Ther"},{"key":"2023050810275821900_R9","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/00054725-200205000-00005","article-title":"Delayed hypersensitivity reaction and acute respiratory distress syndrome following infliximab infusion.","volume":"8","author":"Riegert-Johnson","year":"2002","journal-title":"Inflamm Bowel Dis"},{"key":"2023050810275821900_R10","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1016\/S0140-6736(01)06810-6","article-title":"Infliximab-induced aseptic meningitis.","volume":"358","author":"Marotte","year":"2001","journal-title":"Lancet"},{"key":"2023050810275821900_R11","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1136\/pmj.78.915.47","article-title":"Necrotising fasciitis in a patient receiving infliximab for rheumatoid arthritis.","volume":"78","author":"Chan","year":"2002","journal-title":"Postgrad Med J"},{"key":"2023050810275821900_R12","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1111\/j.1572-0241.2002.05784.x","article-title":"Infliximab retreatment in adults and children with Crohn\u2019s disease: risk factors for the development of delayed severe systemic reaction.","volume":"97","author":"Kugathasan","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"2023050810275821900_R13","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1056\/NEJMoa011110","article-title":"Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent.","volume":"345","author":"Keane","year":"2001","journal-title":"N Engl J Med"},{"key":"2023050810275821900_R14","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/S0002-9394(02)01499-X","article-title":"Multiple bilateral eyelid molluscum contagiosum lesions associated with TNF-alpha antibody and methotrexate therapy.","volume":"134","author":"Cursiefen","year":"2002","journal-title":"Am J Ophthalmol"},{"key":"2023050810275821900_R15","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0002-9343(97)00179-4","article-title":"Clinical presentation and natural course of anogenital warts.","volume":"102","author":"Handsfield","year":"1997","journal-title":"Am J Med"},{"key":"2023050810275821900_R16","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1097\/00007890-200101150-00030","article-title":"Human papilloma virus infection and anogenital condyloma in bone marrow transplant recipients.","volume":"71","author":"Daneshpouy","year":"2001","journal-title":"Transplantation"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/80\/944\/358\/50224604\/postgradmedj-80-358.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/80\/944\/358\/50224604\/postgradmedj-80-358.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T10:29:52Z","timestamp":1683541792000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/80\/944\/358\/7036113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":16,"journal-issue":{"issue":"944","published-online":{"date-parts":[[2004,6,10]]},"published-print":{"date-parts":[[2004,6,10]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.2003.009332","relation":{},"ISSN":["1469-0756","0032-5473"],"issn-type":[{"value":"1469-0756","type":"electronic"},{"value":"0032-5473","type":"print"}],"subject":[],"published-other":{"date-parts":[[2004,6]]},"published":{"date-parts":[[2004,6]]}}}