{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T17:04:40Z","timestamp":1778000680822,"version":"3.51.4"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"963","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,1,1]]},"DOI":"10.1136\/pgmj.2004.020875","type":"journal-article","created":{"date-parts":[[2006,1,5]],"date-time":"2006-01-05T18:34:13Z","timestamp":1136486053000},"page":"36-39","source":"Crossref","is-referenced-by-count":67,"title":["Neurosyphilis with optic neuritis: an update"],"prefix":"10.1093","volume":"82","author":[{"given":"G T","family":"Smith","sequence":"first","affiliation":[{"name":"Western Eye Hospital , London, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Goldmeier","sequence":"additional","affiliation":[{"name":"Genitourinary Department, St Mary's Hospital , London, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Migdal","sequence":"additional","affiliation":[{"name":"Western Eye Hospital , London, England"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2006,1,5]]},"reference":[{"key":"2023042013494147800_bib1","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0140-6736(97)01382-2","article-title":"Epidemics of syphilis in the Russian Federation: trends, origins, and priorities for control","volume":"350","author":"Tichonova","year":"1997","journal-title":"Lancet"},{"key":"2023042013494147800_bib2","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/S0161-6420(90)32419-3","article-title":"Ocular syphilis","volume":"97","author":"Tamesis","year":"1990","journal-title":"Ophthalmology"},{"key":"2023042013494147800_bib3","doi-asserted-by":"crossref","first-page":"855","DOI":"10.7326\/0003-4819-109-11-855","article-title":"Invasion of the central nervous system by Treponema pallidum: implications for diagnosis and treatment","volume":"109","author":"Lukehart","year":"1988","journal-title":"Ann Intern Med"},{"key":"2023042013494147800_bib4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0039-6257(92)90138-J","article-title":"Ocular syphilis","volume":"37","author":"Margo","year":"1992","journal-title":"Surv Ophthalmol"},{"key":"2023042013494147800_bib5","first-page":"1581","volume-title":"Clinical neuro-ophthalmology","author":"Walsh","year":"1969","edition":"3rd ed"},{"key":"2023042013494147800_bib6","doi-asserted-by":"crossref","first-page":"350","DOI":"10.7326\/0003-4819-118-5-199303010-00005","article-title":"Effects of HIV infection on the serologic manifestations and responses to treatment of syphilis in intravenous drug users","volume":"118","author":"Gourevitch","year":"1993","journal-title":"Ann Intern Med"},{"key":"2023042013494147800_bib7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1258\/0956462011924065","article-title":"European guidelines for the management of syphilis","volume":"12","author":"Goh","year":"2001","journal-title":"Int J STD AIDS"},{"key":"2023042013494147800_bib8","first-page":"18","article-title":"Sexually transmitted disease guidelines 2002","volume":"51","author":"Centers for Disease Control and Prevention","year":"2002","journal-title":"MMWR"},{"key":"2023042013494147800_bib9","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1001\/jama.1976.03270200046031","article-title":"Neurosyphilis and penicillin levels in the cerebrospinal fluid","volume":"236","author":"Mohr","year":"1976","journal-title":"JAMA"},{"key":"2023042013494147800_bib10","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1056\/NEJM198706183162503","article-title":"Alteration in the natural history of neurosyphilis by concurrent infection with human immunodeficiency virus","volume":"316","author":"Johns","year":"1987","journal-title":"N Engl J Med"},{"key":"2023042013494147800_bib11","first-page":"71","article-title":"Penetration of ocular compartments by penicillins","volume":"18","author":"Barza","year":"1973","journal-title":"Surv Ophthalmol"},{"key":"2023042013494147800_bib12","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1001\/archinte.1980.00330190129043","article-title":"Failure of penicillin G benzathine in the treatment of neurosyphilis","volume":"140","author":"Greene","year":"1980","journal-title":"Arch Intern Med"},{"key":"2023042013494147800_bib13","first-page":"407","article-title":"Inhibition of growth of treponemes by antimicrobial agents","volume":"47","author":"Abramson","year":"1971","journal-title":"Br J Vener Dis"},{"key":"2023042013494147800_bib14","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1128\/AAC.28.2.347","article-title":"Penetration of oral doxycycline into the cerebrospinal fluid of patients with latent or neurosyphilis","volume":"28","author":"Yim","year":"1985","journal-title":"Antimicrobial Agents Chemother"},{"key":"2023042013494147800_bib15","first-page":"1859","article-title":"Ocular penetration of orally administered minocyclin","volume":"46","author":"Poirer","year":"1951","journal-title":"Ann Ophthalmol"},{"key":"2023042013494147800_bib16","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1128\/AAC.41.11.2522","article-title":"Studies of the killing kinetics of benzylpenicillin, cefuroxime, azithromycin, and sparofloxacin on bacteria in the postantibiotic phase","volume":"41","author":"Odenholt","year":"1997","journal-title":"Antimicrobial Agents Chemother"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/82\/963\/36\/50024641\/postgradmedj-82-36.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/82\/963\/36\/50024641\/postgradmedj-82-36.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T17:01:19Z","timestamp":1682010079000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/82\/963\/36\/7045201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1,1]]},"references-count":16,"journal-issue":{"issue":"963","published-online":{"date-parts":[[2006,1,5]]},"published-print":{"date-parts":[[2006,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.2004.020875","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2006,1]]},"published":{"date-parts":[[2006,1,1]]}}}