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Pyoderma gangrenosum is a severe painful ulcerating disease that requires moist wound management and, in the absence of secondary infection, systemic corticosteroids, cyclosporine, or both. Infliximab may also be used. Erythema nodosum is a common cause of tender red nodules of the shins. Management includes leg elevation, NSAIDs, and potassium iodide. Oral manifestations of IBD include aphthous stomatitis, mucosal nodularity (cobblestoning), and pyostomatitis vegetans. Treatment should be directed both at the cutaneous lesions and at the underlying systemic condition.<\/jats:p>","DOI":"10.1136\/pgmj.2004.031633","type":"journal-article","created":{"date-parts":[[2005,9,2]],"date-time":"2005-09-02T13:13:19Z","timestamp":1125666799000},"page":"580-585","source":"Crossref","is-referenced-by-count":106,"title":["Important cutaneous manifestations of inflammatory bowel disease"],"prefix":"10.1093","volume":"81","author":[{"given":"L B","family":"Trost","sequence":"first","affiliation":[{"name":"Department of Dermatology, Cleveland Clinic Foundation , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J K","family":"McDonnell","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Cleveland Clinic Foundation , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2005,9,2]]},"reference":[{"key":"2023042408394187300_R1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0889-8553(01)00002-4","article-title":"Epidemiology of inflammatory bowel disease.","volume":"31","author":"Loftus","year":"2002","journal-title":"Gastroenterol Clin North Am"},{"key":"2023042408394187300_R2","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1056\/NEJMra020831","article-title":"Inflammatory bowel disease.","volume":"347","author":"Podolsky","year":"2002","journal-title":"N Engl J Med"},{"key":"2023042408394187300_R3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1001\/archinte.1988.00380020041008","article-title":"Extraintestinal manifestations of idiopathic inflammatory bowel disease.","volume":"148","author":"Danzi","year":"1988","journal-title":"Arch Intern Med"},{"key":"2023042408394187300_R4","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1046\/j.1468-3083.2000.00137.x","article-title":"Cutaneous manifestations of inflammatory bowel disease.","volume":"15","author":"Berkowitz","year":"2000","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023042408394187300_R5","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/00005792-197609000-00004","article-title":"The extraintestinal manifestations of Crohn\u2019s disease and ulcerative colitis: a study of 700 patients.","volume":"55","author":"Greenstein","year":"1976","journal-title":"Medicine"},{"key":"2023042408394187300_R6","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0190-9622(92)70059-O","article-title":"Cutaneous manifestations of gastrointestinal disorders. 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