{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:24:54Z","timestamp":1790922294895,"version":"4.1.0"},"reference-count":56,"publisher":"Oxford University Press (OUP)","issue":"978","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>It is well-established that prolonged and severe vitamin D deficiency leads to rickets in children and osteomalacia in adults. More marginal vitamin D deficiency is likely to be a significant contributing factor to osteoporosis risk. However, recent emerging data from studies of adults suggest that low vitamin D status (serum 25-hydroxyvitamin D levels &amp;lt;50 nmol\/l) may be contributing to the development of various chronic diseases, including cardiovascular disease, hypertension, diabetes mellitus, some inflammatory and autoimmune diseases, and certain cancers. Adequacy of vitamin D status in children and adolescents has been the focus of a number of recent investigations, and these studies have shown a high prevalence of low vitamin D status during the winter (especially in adolescents), with lower prevalence during the summer. Therefore, consideration of potential corrective strategies to allow children and adolescents to maintain adequate vitamin D status throughout the year, even in the absence of adequate summer sun exposure, is warranted.<\/jats:p>","DOI":"10.1136\/pgmj.2006.052787","type":"journal-article","created":{"date-parts":[[2007,4,2]],"date-time":"2007-04-02T17:58:50Z","timestamp":1175536730000},"page":"230-235","source":"Crossref","is-referenced-by-count":107,"title":["Vitamin D in childhood and adolescence"],"prefix":"10.1093","volume":"83","author":[{"given":"Kevin D","family":"Cashman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2007,4,2]]},"reference":[{"key":"2023042013000630900_bib1","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1093\/ajcn\/36.5.1014","article-title":"Vitamin D and bone health in the elderly","volume":"36","author":"Parfitt","year":"1982","journal-title":"Am J Clin Nutr"},{"key":"2023042013000630900_bib2","volume-title":"for calcium, phosphorous, magnesium, vitamin D and fluoride","author":"Institute of Medicine. 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