{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:14:49Z","timestamp":1790421289473,"version":"4.1.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"1005","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>We prospectively studied patients referred to secondary care with acute tonsillitis, peritonsillar cellulitis and quinsy (peritonsillar abscess) to see if recommended treatment guidelines were being followed and whether antibiotic resistance was contributing to admission.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Study design<\/jats:title>\n                  <jats:p>Prospective observational study in a university teaching hospital of 90 consecutive patients admitted to secondary care over an 18 month period with acute tonsillitis, peritonsillar cellulitis or quinsy were studied. The geographical distribution by postcode, pre-admission history and treatment of each patient was recorded. The patients\u2019 general practitioners (GPs) were questioned about the patients\u2019 history, their use of antibiotics and prescribing guidelines and a patient questionnaire was completed. The result of hospital admission including throat swabs and blood cultures were recorded together with their treatment and outcome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>58% (n\u200a=\u200a28) of patients who were prescribed antibiotics before admission received an inadequate dose or inappropriate antibiotic. Only 56% (n\u200a=\u200a45) of GPs said they used guidelines for the treatment of acute sore throat. In 34 cases an organism was isolated, with 33 (97%) being sensitive to penicillin. No resistant organisms were isolated. Hospital doctors prescribed antibiotics contrary to guidelines in 39% (n\u200a=\u200a35) of cases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Antibiotic resistance was not demonstrated in this study. Adherence to guidelines for prescribing antibiotics in patients with features of group A \u03b2-haemolytic streptococcal sore throat is poor. Information support may help to improve prescribing.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/pgmj.2008.076059","type":"journal-article","created":{"date-parts":[[2009,7,6]],"date-time":"2009-07-06T04:01:08Z","timestamp":1246852868000},"page":"347-351","source":"Crossref","is-referenced-by-count":6,"title":["Prescribing antibiotics for sore throat: adherence to guidelines in patients admitted to hospital"],"prefix":"10.1093","volume":"85","author":[{"given":"N J","family":"Clifton","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head & Neck Surgery, Queens Medical Centre, University Hospital , Nottingham , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U","family":"Raghavan","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head & Neck Surgery, Queens Medical Centre, University Hospital , Nottingham , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Birkin","sequence":"additional","affiliation":[{"name":"Health Protection Agency, East Midlands, City Hospital , Nottingham , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N S","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head & Neck Surgery, Queens Medical Centre, University Hospital , Nottingham , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,7,5]]},"reference":[{"key":"2023041909290891400_b1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1093\/fampra\/13.3.317","article-title":"Sore throat management in general practice","volume":"13","author":"Little","year":"1996","journal-title":"Fam Pract"},{"key":"2023041909290891400_b2","article-title":"Antibiotics for sore throat. Cochrane Database of Systematic Reviews (2006) Issue 4. Art. No.: CD000023. doi: 10.1002\/14651858.CD000023.pub3.","author":"Del Mar"},{"key":"2023041909290891400_b3","first-page":"657","article-title":"Respiratory illness and antibiotic use in general practice","volume":"21","author":"Howie","year":"1971","journal-title":"J R Coll Gen Pract"},{"key":"2023041909290891400_b4","first-page":"45","article-title":"Use of antibiotics for sore throat and incidence of quinsy","volume":"57","author":"Dunn","year":"2007","journal-title":"Br J Gen Pract"},{"key":"2023041909290891400_b5","first-page":"817","article-title":"How effective are treatments other than antibiotics for acute sore throat ?","volume":"50","author":"Thomas","year":"2000","journal-title":"Br J Gen Pract"},{"key":"2023041909290891400_b6","article-title":"Management of sore throat and indications for tonsillectomy: a national clinical guideline. Report No 34. Edinburgh: SIGN, 1999","author":"Scottish Intercollegiate Guidelines Network"},{"key":"2023041909290891400_b7","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1136\/bmj.326.7381.138","article-title":"Why do general practitioners prescribe antibiotics for sore throat? Grounded theory interview study","volume":"326","author":"Kumar","year":"2003","journal-title":"BMJ"},{"key":"2023041909290891400_b8","volume-title":"The path of least resistance","author":"Standing Medical Advisory Committee Sub-Group on Anti-Microbial Resistance","year":"1998"},{"key":"2023041909290891400_b9","article-title":"Prescribing of antibiotics for self-limiting respiratory tract infections in adults and children in primary care. London: NICE, 2008","author":"National Institute for Health and Clinical Excellence"},{"issue":"(3)","key":"2023041909290891400_b10","first-page":"12","article-title":"Sore throat","volume":"17","author":"MeReC","year":"2006","journal-title":"MeReC Bulletin"},{"key":"2023041909290891400_b11","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1542\/peds.2008-0488","article-title":"Performance of a rapid antigen-detection test and throat culture in community pediatric offices: implications for management of pharyngitis","volume":"123","author":"Tanz","year":"2009","journal-title":"Pediatrics"},{"key":"2023041909290891400_b12","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1177\/0272989X8100100304","article-title":"The diagnosis of streptococcal throat in the emergency room","volume":"1","author":"Centor","year":"1981","journal-title":"Med Decis Making"},{"key":"2023041909290891400_b13","article-title":"NHS Clinical Knowledge Summaries CKS. 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