{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:24:22Z","timestamp":1761675862308},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"1031","license":[{"start":{"date-parts":[[2011,6,9]],"date-time":"2011-06-09T00:00:00Z","timestamp":1307577600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,9,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To ascertain the impact of uterine leiomyomas on pregnancy outcome, and to determine the effectiveness of myomectomy at the time of caesarean delivery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective study was conducted on pregnant women with uterine leiomyomas. Clinical information including the course of the pregnancy, mode of delivery, pathology findings, and postpartum course were extracted from medical records and analysed for statistical significance.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There were 50 pregnancies associated with uterine leiomyomas. During pregnancy, the leiomyomas grew &amp;gt;2\u2005cm in 46% of cases. Only 6% were affected by symptoms of red degeneration. There were 2% mid trimester inductions of labour, 6% vaginal deliveries, and 92% caesarean sections. Of the 46 caesarean sections, 47% were due to obstetrical factors and 89% of patients underwent myomectomy at the time of caesarean delivery. The mean blood loss from myomectomy at the time of caesarean section was 260\u2005ml (200\u2013700\u2005ml), and 5% of patients who underwent myomectomy were transfused.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>It is possible to carry a pregnancy successfully to term when the pregnancy is complicated by uterine leiomyomas. When caesarean delivery is needed, myomectomy can be performed at the time of caesarean section routinely without significant complications.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/pgmj.2009.089748","type":"journal-article","created":{"date-parts":[[2011,6,10]],"date-time":"2011-06-10T08:50:56Z","timestamp":1307695856000},"page":"601-604","source":"Crossref","is-referenced-by-count":12,"title":["Successful pregnancies with uterine leiomyomas and myomectomy at the time of caesarean section"],"prefix":"10.1093","volume":"87","author":[{"given":"Yu-Lan","family":"Mu","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University , Jinan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University , Jinan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology, Medical College of Shandong University , Jinan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University , Jinan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank D","family":"Yelian","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Wayne State University School of Medicine , Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xie-Tong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University , Jinan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2011,6,9]]},"reference":[{"key":"2023041908335170700_b1","first-page":"3","article-title":"Changes in uterine myoma dimentions during pregnancy","volume":"46","author":"Bosev","year":"2007","journal-title":"Akush Ginekol (Sofiia)"},{"key":"2023041908335170700_b2","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1159\/000052997","article-title":"Can myomectomy be performed during pregnancy?","volume":"53","author":"Celik","year":"2002","journal-title":"Gynecol Obstet Invest"},{"key":"2023041908335170700_b3","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1093\/humrep\/deg318","article-title":"Successful myomectomy during pregnancy","volume":"18","author":"Lolis","year":"2003","journal-title":"Hum Reprod"},{"key":"2023041908335170700_b4","first-page":"182","article-title":"Obstetric characteristics and perinatal outcome of pregnancies with uterine leiomyomas","volume":"49","author":"Sheiner","year":"2004","journal-title":"J Reprod Med"},{"key":"2023041908335170700_b5","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1080\/09513590600604673","article-title":"Effects of the position of leiomyomas on fertility","volume":"22","author":"Casini","year":"2006","journal-title":"Gynecol Endocrinol"},{"key":"2023041908335170700_b6","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.bpobgyn.2008.01.008","article-title":"Clinical presentation of fibroids","volume":"22","author":"Gupta","year":"2008","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"2023041908335170700_b7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ajog.2007.12.039","article-title":"Leiomyomas and reproductive outcomes: a systematic literature review from conception to delivery","volume":"198","author":"Klatsky","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"2023041908335170700_b8","first-page":"764","article-title":"Complications in pregnancy, labor, and delivery with uterine leiomyomas: a population-based study","volume":"95","author":"Coronado","year":"2000","journal-title":"Obstet Gynecol"},{"key":"2023041908335170700_b9","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ijgo.2004.12.035","article-title":"Myomectomy during cesarean section","volume":"89","author":"Kaymak","year":"2005","journal-title":"Int J Gynaecol Obstet"},{"key":"2023041908335170700_b10","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1196\/annals.1365.038","article-title":"Myomectomy during cesarean section: a safe procedure?","volume":"1092","author":"Hassiakos","year":"2006","journal-title":"Ann N Y Acad Sci"},{"key":"2023041908335170700_b11","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1080\/01443610802462712","article-title":"Fertility and obstetric outcome after caesarean myomectomy","volume":"28","author":"Adesiyun","year":"2008","journal-title":"J Obstet Gynaecol"},{"key":"2023041908335170700_b12","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/S0020-7292(01)00452-0","article-title":"Myomectomy during cesarean section","volume":"75","author":"Ehigiegba","year":"2001","journal-title":"Int J Gynecol Obstet"},{"key":"2023041908335170700_b13","doi-asserted-by":"crossref","first-page":"38","DOI":"10.2307\/3583255","article-title":"Cesarean myomectomy","volume":"6","author":"Kwawukume","year":"2002","journal-title":"Afr J Reprod Health"},{"key":"2023041908335170700_b14","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1471-2393-4-14","article-title":"Myomectomy at time of cesarean delivery: a retrospective cohort study","volume":"4","author":"Roman","year":"2004","journal-title":"BMC Pregnancy Childbirth"},{"key":"2023041908335170700_b15","first-page":"593","article-title":"Complications of uterine leiomyomas in pregnancy","volume":"73","author":"Katz","year":"1989","journal-title":"Obstet Gynecol"},{"key":"2023041908335170700_b16","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.bpobgyn.2009.01.012","article-title":"Acute complications of fibroids","volume":"23","author":"Gupta","year":"2009","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"2023041908335170700_b17","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.jmig.2005.05.012","article-title":"Isobaric (gasless) laparoscopic myomectomy during pregnancy","volume":"12","author":"Melgrati","year":"2005","journal-title":"J Minim Invasive Gynecol"},{"key":"2023041908335170700_b18","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/00016340802635526","article-title":"Myomectomy during cesarean section","volume":"88","author":"Li","year":"2009","journal-title":"Acta Obstet Gynecol Scand"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/87\/1031\/601\/50019461\/postgradmedj-87-601.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/87\/1031\/601\/50019461\/postgradmedj-87-601.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T08:51:09Z","timestamp":1681894269000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/87\/1031\/601\/7031940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,9]]},"references-count":18,"journal-issue":{"issue":"1031","published-online":{"date-parts":[[2011,6,9]]},"published-print":{"date-parts":[[2011,9,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.2009.089748","relation":{},"ISSN":["1469-0756","0032-5473"],"issn-type":[{"value":"1469-0756","type":"electronic"},{"value":"0032-5473","type":"print"}],"subject":[],"published-other":{"date-parts":[[2011,9]]},"published":{"date-parts":[[2011,6,9]]}}}