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(1930): Sclerosis of the Pulmonary Artery with Thrombosis, Lancet, ii, 911.","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/00000441-192707000-00005","article-title":"Ayerza's Disease: with a report of two cases","volume":"174","author":"CHENEY, G.; C.L.A.R.K.E.","year":"1927","unstructured":"CHENEY, G., and CLARKE (1927): Ayerza's Disease: with a report of two cases, Amer. J. med. Sci., 174, 34.","journal-title":"Amer. J. med. Sci"},{"key":"ref_4","author":"DALEY, R.","year":"1960","unstructured":"DALEY, R., in DALEY, R., GOODWIN, J. F., and STEINER, R. E., Ed. (1960): Clinical Disorders of the Pulmonary","journal-title":"Clinical Disorders of the Pulmonary"},{"key":"ref_5","first-page":"2","article-title":"Significance of Pulmonary Vascular Bed in Congenital Heart Disease: Defects between Ventricles or Great Vessels in which Both Increased Pressure and Blood Flow may act upon Lungs and in which there is Common Ejectile Force, Amer","volume":"52","author":"DAMMANN, Jr., J.F.; FERENCZ, C.","year":"1956","unstructured":"DAMMANN, J. F., Jr., and FERENCZ, C. (1956): Significance of Pulmonary Vascular Bed in Congenital Heart Disease: Defects between Ventricles or Great Vessels in which Both Increased Pressure and Blood Flow may act upon Lungs and in which there is Common Ejectile Force, Amer. Heart Y., 52, 2IO.","journal-title":"Heart Y"},{"key":"ref_6","first-page":"270","author":"DAWES, G.S.","year":"1959","unstructured":"DAWES, G. S., in ADAMS, W. R., and VEITH, I., Ed. (1959): Pulmonary Circulation, p. 270. New York: Grune & Stratton.","journal-title":"Pulmonary Circulation"},{"key":"ref_7","first-page":"105","article-title":"Pulmonary Artery Thrombosis Simulating Pulmonic Valve Stenosis with Patent Foramen Ovale, Amer","volume":"47","author":"DIMOND, E.G.; JONES, T.R.","year":"1954","unstructured":"DIMOND, E. G., and JONES, T. R. (1954): Pulmonary Artery Thrombosis Simulating Pulmonic Valve Stenosis with Patent Foramen Ovale, Amer. Heart Y., 47, 105.","journal-title":"Heart Y"},{"key":"ref_8","first-page":"64","article-title":"Functional Pathology of the Pulmonary Vascular Tree in Congenital Cardiac","volume":"5","author":"EDWARDS, J.E.","year":"1957","unstructured":"EDWARDS, J. E. (1957): Functional Pathology of the Pulmonary Vascular Tree in Congenital Cardiac Disease, Circulation, I5, I64.","journal-title":"Disease, Circulation"},{"key":"ref_9","first-page":"270","article-title":"Clinical Disorders of the Pulmonary Circulation","author":"GOODWIN, J.F.","year":"1960","unstructured":"GOODWIN, J. F., in DALEY, R., GOODWIN, J. F., and STEINER, R. E., Ed. (1960): Clinical Disorders of the Pulmonary Circulation, p. 270. London: J. & A. Churchill."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1136\/hrt.17.2.207","article-title":"Thrombosis of Main Pulmonary Arteries, Brit","volume":"17","author":"MAGIDSON, O.; JACOBSON, G.","year":"1955","unstructured":"MAGIDSON, O., and JACOBSON, G. (1955): Thrombosis of Main Pulmonary Arteries, Brit. Heart J., 17, 207.","journal-title":"Heart J"},{"key":"ref_11","article-title":"Thrombosis of Pulmonary Vessels in Polycythoemia Vera, Y","volume":"254","author":"POLL, D.","year":"1935","unstructured":"POLL, D. (1935): Thrombosis of Pulmonary Vessels in Polycythoemia Vera, Y. Mount Sinai Hos., I, 254.","journal-title":"Mount Sinai Hos"},{"key":"ref_12","first-page":"298","article-title":"Die Erkrankungen der Lungenschlagader, Ergebn","volume":"13","author":"POSSELT, A.","year":"1909","unstructured":"POSSELT, A. (1909): Die Erkrankungen der Lungenschlagader, Ergebn. allg. Path. Path. Anat., 13, 298.","journal-title":"allg. Path. Path. Anat"},{"key":"ref_13","first-page":"42","article-title":"Chronic Massive Pulmonary Artery Thrombosis, Ann","volume":"43","author":"RING, A.; BAKKE, J.R.","year":"1955","unstructured":"RING, A., and BAKKE, J. R. (1955): Chronic Massive Pulmonary Artery Thrombosis, Ann. Intern. Med., 43, 78I. SAVACOOL, J. W., and CHARR, R. (1941): Thrombosis of Pulmonary Artery, Amer. Rev. Tuberc., 44, 42.","journal-title":"Intern. Med"},{"key":"ref_14","first-page":"832","article-title":"Diseases of the Heart and Circulation","volume-title":"The Eisenmenger Svndrome, or Pulmonary Hypertension","author":"WOOD, P.","year":"1956","unstructured":"WOOD, P. (1956): Diseases of the Heart and Circulation, p. 832. London: Eyre and Spottiswoode. -, P. (1958): The Eisenmenger Svndrome, or Pulmonary Hypertension, with Reversed Central Shunt, Brit."},{"key":"ref_15","article-title":"HT) and an excessive quantity of this substance produces a remarkable syndrome in patients suffering from metastasizing carcinoids with atypical cyanosis, flushing, diarrhaea, asthma-like attacks and, in the late stages, valvular diseases of the right side of the heart (Bi6rck, Axen and Thornsen, I952 and Thornsen, Biorck, Bjorkman and Waldenstrom, I954). The bizarre and inconstant nature of the symptoms can lead to diagnostic error as happened in the following case, the diagnosis of which was not established during life","unstructured":"(5-HT) and an excessive quantity of this substance produces a remarkable syndrome in patients suffering from metastasizing carcinoids with atypical cyanosis, flushing, diarrhaea, asthma-like attacks and, in the late stages, valvular diseases of the right side of the heart (Bi6rck, Axen and Thornsen, I952 and Thornsen, Biorck, Bjorkman and Waldenstrom, I954). The bizarre and inconstant nature of the symptoms can lead to diagnostic error as happened in the following case, the diagnosis of which was not established during life."},{"key":"ref_16","article-title":"Case Report A 67-year-old taxi-driver, previously in good health, had a ' heart attack ' in 1958 and ' chest trouble ' in April, 1959. In August, 1959, while driving, he fainted, hit a car ahead and received head injuries for vhich he w!as treated in the hospital. Otn examination his abdonen was found to be tense and rigid. All other clinical and relevant laboratory findings were wvithini normiia limits. In I960, from May to July, he was investigated for loss of weight, intermittent back and abdominal pain, episodic diarrhcea and poor urinary stream. Examination revealed periodic increase of muscle tone. At no time was the urinary excretion of 5-hydroxy-indole acetic acid in the urine determined","unstructured":"Case Report A 67-year-old taxi-driver, previously in good health, had a ' heart attack ' in 1958 and ' chest trouble ' in April, 1959. In August, 1959, while driving, he fainted, hit a car ahead and received head injuries for vhich he w!as treated in the hospital. Otn examination his abdonen was found to be tense and rigid. All other clinical and relevant laboratory findings were wvithini normiia limits. In I960, from May to July, he was investigated for loss of weight, intermittent back and abdominal pain, episodic diarrhcea and poor urinary stream. Examination revealed periodic increase of muscle tone. At no time was the urinary excretion of 5-hydroxy-indole acetic acid in the urine determined."},{"key":"ref_17","article-title":"Even with widespread metastases long periods of survival have been recorded","year":"1940","unstructured":"Even with widespread metastases long periods of survival have been recorded (Cope, I930; Mallory 1940)."},{"key":"ref_18","article-title":"The extensive metastases in this patient suggest that he had had this tumour for a long time. Had all his symptoms since 1958 been correlated and due attention paid to his permanently red face","volume-title":"POSTGRADUATE MEDICAL JOURNAL","unstructured":"The extensive metastases in this patient suggest that he had had this tumour for a long time. Had all his symptoms since 1958 been correlated and due attention paid to his permanently red face, POSTGRADUATE MEDICAL JOURNAL"},{"key":"ref_19","article-title":"on the other hand have produced evidence by using several anti-metabolites that cerebral deficiency of 5-HT is probably responsible for the mental change. The latter view has been strengthened by the observation of Gaddum","author":"Woolley; Shaw","year":"1954","unstructured":"Woolley and Shaw (1954) on the other hand have produced evidence by using several anti-metabolites that cerebral deficiency of 5-HT is probably responsible for the mental change. The latter view has been strengthened by the observation of Gaddum (1953)."},{"key":"ref_20","article-title":"Although our knowledge of the cerebral metabolism of serotonin and the enzymes that form and destroy it, the substance that activates and blocks the enzymes to produce excess or deficiency of 5-HT, is insufficient, it is generally recognized that many substances such as LSD, harmala alkaloids (Woolley and Shaw, 1954) and 5-HTP (Smith, I960) cause mental disturbance by upsetting the","unstructured":"Although our knowledge of the cerebral metabolism of serotonin and the enzymes that form and destroy it, the substance that activates and blocks the enzymes to produce excess or deficiency of 5-HT, is insufficient, it is generally recognized that many substances such as LSD, harmala alkaloids (Woolley and Shaw, 1954) and 5-HTP (Smith, I960) cause mental disturbance by upsetting the"},{"key":"ref_21","first-page":"596","article-title":"The Distribution of Substance P and 5-Hvdroxytrvptamine in the","volume":"26","author":"ArNIIN, A.H.; CRAWFORD, T.A.B.; GADDUM, J.H.","year":"1954","unstructured":"ArNIIN, A. H., CRAWFORD, T. A. B., and GADDUM, J. H. (1954): The Distribution of Substance P and 5-Hvdroxytrvptamine in the Central Nervous System of Dog, Y. Physiol. (Lond.), I26, 596.","journal-title":"Central Nervous System of Dog, Y. Physiol. (Lond.)"},{"key":"ref_22","first-page":"43","article-title":"Unusual Cvanosis in a Boy vith Congenital Pulmonary-Stenosis and Tricuspid Valve Insufficiency, Fatal Outcome, Amer","volume":"44","year":"1952","unstructured":"BI1RCK, G., AXEN, 0., and THORSON, A. (1952): Unusual Cvanosis in a Boy vith Congenital Pulmonary-Stenosis and Tricuspid Valve Insufficiency, Fatal Outcome, Amer. Heart J., 44, I43.","journal-title":"Heart J"},{"key":"ref_23","first-page":"63","article-title":"A Concept for a Role of Serotonin and Norepinephrine as Chemical Mediator in the","volume":"66","author":"BRODIE, B.B.; SHORE, P.A.","year":"1957","unstructured":"BRODIE, B. B., and SHORE, P. A. (1957): A Concept for a Role of Serotonin and Norepinephrine as Chemical Mediator in the Brain, Ann. N.Y. Acad. Sci., 66, 63I.","journal-title":"Brain, Ann. N. Y. Acad. Sci"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1464-410X.1930.tb00005.x","article-title":"Metastases of Argentaffin Carcinoma in Testicle, Brit","volume":"2","author":"COPE, Z.","year":"1930","unstructured":"COPE, Z. (1930): Metastases of Argentaffin Carcinoma in Testicle, Brit. J. Urol., 2, 268.","journal-title":"J. Urol"},{"key":"ref_25","first-page":"48","article-title":"Injections of Drugs into the Lateral Ventricle of Cat, Y","volume":"123","author":"FELDBERG, W.; SHERWOOD, S.L.","year":"1954","unstructured":"FELDBERG, W., and SHERWOOD, S. L. (1954): Injections of Drugs into the Lateral Ventricle of Cat, Y. Pl?ysiol. (Lond.), 123, I48.","journal-title":"Pl?ysiol. (Lond.)"},{"key":"ref_26","first-page":"5","article-title":"Antagonism between Lysergic Acid Diethylamide and 5-hvdroxytrvptamine, Y","volume":"121","author":"GADDUNI, J.H.","year":"1953","unstructured":"GADDUNI, J. H. (1953): Antagonism between Lysergic Acid Diethylamide and 5-hvdroxytrvptamine, Y. Physiol. (Lond.), 121, I 5.","journal-title":"Physiol. (Lond.)"},{"key":"ref_27","first-page":"686","article-title":"Case Records of the Massachusetts General Hospital, New: Engl","volume":"222","author":"MALLORY, T.B.","year":"1940","unstructured":"MALLORY, T. B. (1940): Case Records of the Massachusetts General Hospital, New: Engl. Y. iMed., 222, 686.","journal-title":"Y. iMed"},{"key":"ref_28","first-page":"365","article-title":"Relationship of Hallucinogens to Adrenergic","volume":"121","author":"MARRAZZI, A.S.; HARTS, E.R.","year":"1955","unstructured":"MARRAZZI, A. S., and HARTS, E. R. (1955): Relationship of Hallucinogens to Adrenergic Cerebral Neurohumors, Science, 121, 365.","journal-title":"Cerebral Neurohumors, Science"},{"key":"ref_29","first-page":"157","article-title":"Serotonin Content of Some Mammalian Tissues, Urine and Mlethod for its Determination, Amer","volume":"175","author":"PAGE, I.H.; TWAROG, B.M.","year":"1953","unstructured":"PAGE, I. H., and TWAROG, B. M. (1953): Serotonin Content of Some Mammalian Tissues, Urine and Mlethod for its Determination, Amer. Y. Physiol., 175, 157.","journal-title":"Y. Physiol"},{"key":"ref_30","first-page":"127","article-title":"Action of Serotonin on Vagal Afferent Impulses in Cat, Amer","volume":"174","author":"SCHNEIDER, J.A.; YONKMAN, F.F.","year":"1953","unstructured":"SCHNEIDER, J. A., and YONKMAN, F. F. (1953): Action of Serotonin on Vagal Afferent Impulses in Cat, Amer. Y. Physiol., 174, 127.","journal-title":"Y. Physiol"},{"key":"ref_31","first-page":"795","article-title":"Malignant Carcinoid of the Small Intestine with Metastases to the Liver, Valvular Disea3e of the Right Side of the Heart, Peripheral Vasomotor Symptoms, Bronchoconstriction and an Unusual Type of Cyanosis: A Clinical and Pathological Svndrome, Amer. Heart 5'","volume":"47","author":"THORSON, A.; BIORCK, A.; BJORKMAN, G.; WALDENSTROM, J.","year":"1954","unstructured":"THORSON, A., BIORCK, A., BJORKMAN, G., and WALDENSTROM, J. (1954): Malignant Carcinoid of the Small Intestine with Metastases to the Liver, Valvular Disea3e of the Right Side of the Heart, Peripheral Vasomotor Symptoms, Bronchoconstriction and an Unusual Type of Cyanosis: A Clinical and Pathological Svndrome, Amer. Heart 5'. 47, 795."},{"key":"ref_32","first-page":"272","article-title":"The Distribution of Serotonin, s-Hvdroxytrvptophan Decarboxylase and Monoamine Oxidase in the","volume":"5","author":"UNDENFRIEND, S.; WEISSBACH, H.; BOGDANSKI, D.F.","year":"1957","unstructured":"UNDENFRIEND, S., WEISSBACH, H., and BOGDANSKI, D. F. (1957): The Distribution of Serotonin, s-Hvdroxytrvptophan Decarboxylase and Monoamine Oxidase in the Brain, 5. Neurochem., I, 272.","journal-title":"Brain"},{"key":"ref_33","article-title":"Some Neurophvsiological Aspects of Serotonin, Brit","volume":"122","author":"WOOLLEY, D.W.; SHAW, E.","year":"1954","unstructured":"WOOLLEY, D. W., and SHAW, E. (1954): Some Neurophvsiological Aspects of Serotonin, Brit. med. 5'., ii, 122.","journal-title":"med. 5'"},{"key":"ref_34","article-title":"reporting a series of cases of acute osteomyelitis, found the ulna to be the site of infection in four of one hundred patients","author":"Trueta; Morgan","year":"1954","unstructured":"Trueta and Morgan (1954) reporting a series of cases of acute osteomyelitis, found the ulna to be the site of infection in four of one hundred patients."},{"key":"ref_35","article-title":"in his series, found two in 50 patients","volume-title":"found the ulna involved in nine, in their series of 99 patients","author":"Blanche","year":"1952","unstructured":"Blanche (1952) in his series, found two in 50 patients. Green, Nyhan and Fousek (1956) found the ulna involved in nine, in their series of 99 patients."},{"key":"ref_36","article-title":"Acute and chronic pyogenic osteomyelitis, in adults, are even less common conditions. Reviewing the literature of the past 35 years, a direct reference to the conditions could be found on three occasions ortly","author":"Dufour","year":"1935","unstructured":"Acute and chronic pyogenic osteomyelitis, in adults, are even less common conditions. Reviewing the literature of the past 35 years, a direct reference to the conditions could be found on three occasions ortly. Variava (1935) described the acute condition in a patient with a compound fracture of both forearm bones. The radius, however, was involved maximally. Dufour (1933) demonstrated the radiological history of one patient with chronic","journal-title":"Variava; described the acute condition in a patient with a compound fracture of both forearm bones. 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