{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T19:14:28Z","timestamp":1769454868814,"version":"3.49.0"},"reference-count":107,"publisher":"Oxford University Press (OUP)","issue":"511","license":[{"start":{"date-parts":[[1968,5,1]],"date-time":"1968-05-01T00:00:00Z","timestamp":-52704000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1968,5,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Studies of thyroid stimulating activity of serum from thyrotoxic patients has revealed an abnormal prolonged response in the mouse present in 40-60% of patients depending on the criteria used. This agent designated long acting thyroid stimulator (LATS) is a 7S globulin. Transplacental passage of LATS accounts for neonatal thyrotoxicosis\u2014a self-limited disease. LATS is also more readily detected in patients with large goitre, exophthalmos, pretibial myxoedema and recurrence following therapy. Thyroid ablation is usually followed by a fall in the level of LATS. A fall may also be produced by steroid therapy or immunosuppressive agents. LATS probably arises from lymphoid tissue which accounts for the non-suppressibility of the hypersecreting thyroid. Its discovery provides strong evidence that hyperthyroidism is often, though not always, a disorder of immunological tolerance.<\/jats:p>","DOI":"10.1136\/pgmj.44.511.363","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:20:12Z","timestamp":1230582012000},"page":"363-376","source":"Crossref","is-referenced-by-count":21,"title":["The aetiology and pathogenesis of hyperthyroidism"],"prefix":"10.1093","volume":"44","author":[{"given":"Basil S","family":"Hetzel","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Adelaide, The Queen Elizabeth Hospital , Woodville, South Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1968,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1210\/jcem-18-7-699","article-title":"The presence of an abnormal thyroid stimulating hormone in the serum of some thyrotoxic patients","volume":"18","author":"ADAMS, D.D.","year":"1958","unstructured":"ADAMS, D.D. (1958) The presence of an abnormal thyroid stimulating hormone in the serum of some thyrotoxic patients. J. clin. Endocr. 18, 669.","journal-title":"J. clin. Endocr"},{"key":"ref_2","first-page":"799","article-title":"Bioassay of long acting thyroid stimulator","volume":"21","author":"ADAMS, D.D.","year":"1961","unstructured":"ADAMS, D.D. (1961) Bioassay of long acting thyroid stimulator (L.A.T.S.). The dose response relationship. J. clin. Endocr. 21, 799.","journal-title":"J. clin. Endocr; The dose response relationship"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1136\/bmj.1.5441.1015","article-title":"Pathogenesis of the hyperthyroidism of Graves'","volume":"i,","author":"ADAMS, D.D.","year":"1965","unstructured":"ADAMS, D.D. (1965) Pathogenesis of the hyperthyroidism of Graves' Disease. Brit. med. J. i, 1015.","journal-title":"Disease. Brit. med. J"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1210\/jcem-25-5-571","article-title":"Evidence of a normally functioning pituitary TSH secretion mechanism in a patient with a high blood level of long-acting thyroid stimulator","volume":"25","author":"ADAMS, D.D.; KENNEDY, T.H.","year":"1965","unstructured":"ADAMS, D.D. & KENNEDY, T.H. (1965) Evidence of a normally functioning pituitary TSH secretion mechanism in a patient with a high blood level of long-acting thyroid stimulator. J. clin. Endocr. 25, 571.","journal-title":"J. clin. Endocr"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1210\/endo-70-6-801","article-title":"Failure of TSH antisera to neutralise long acting thyroid stimulator","volume":"70","author":"ADAMS, D.D.; KENNEDY, T.H.; PURVES, H.D.; SIRETr, N.","year":"1962","unstructured":"ADAMS, D.D., KENNEDY, T.H., PURVES, H.D. & SIRETr, N. (1962) Failure of TSH antisera to neutralise long acting thyroid stimulator. Endocrinology, 70, 801.","journal-title":"Endocrinology"},{"key":"ref_6","first-page":"192","article-title":"Neutralization of long acting thyroid stimulator by antibodies to euthyroid human serum","volume":"14","author":"ADAMS, D.D.; SHARARD, A.","year":"1965","unstructured":"ADAMS, D.D. & SHARARD, A. (1965) Neutralization of long acting thyroid stimulator by antibodies to euthyroid human serum. Aust. Ann. Med. 14, 192.","journal-title":"Aust. Ann. Med"},{"key":"ref_7","article-title":"Autoimmunity and thyrotoxicosis","author":"ANDERSON, J.R.; GRAY, K.G.; MIDDLETON, D.G.; YOUNG, J.A.","year":"1964","unstructured":"ANDERSON, J.R., GRAY, K.G., MIDDLETON, D.G. & YOUNG, J.A. (1964) Autoimmunity and thyrotoxicosis. Brit. med. J.","journal-title":"Brit. med. J"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/0014-4827(63)90197-6","article-title":"Gammaglobulin production by human lymphocytes in vitro","volume":"32","author":"BACH, F.; HIRSCHHORN, K.","year":"1963","unstructured":"BACH, F. & HIRSCHHORN, K. (1963) Gammaglobulin production by human lymphocytes in vitro. Exp. Cell Res. 32, 592.","journal-title":"Exp. Cell Res"},{"key":"ref_9","article-title":"Heredity of Graves Disease","volume-title":"Radioactive iodine therapy for progressive malignant exophthalmos. Acta endocr","author":"BARTELS, E.D.","year":"1941","unstructured":"BARTELS, E.D. (1941) Heredity of Graves Disease. Munksgaard, Copenhagen. BAUER, F.K. & CATZ, B. (1966) Radioactive iodine therapy for progressive malignant exophthalmos. Acta endocr."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1172\/JCI105369","article-title":"Inhibition of long acting thyroid stimulator by thyroid particulate fractions","volume":"45","author":"BEALL, G.N.; SOLOMON, D.H.","year":"1966","unstructured":"BEALL, G.N. & SOLOMON, D.H. (1966a) Inhibition of long acting thyroid stimulator by thyroid particulate fractions. J. clin. Invest. 45, 552.","journal-title":"J. clin. Invest"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1210\/jcem-26-12-1382","article-title":"On the immunological nature of the long acting thyroid stimulator","volume":"26","author":"BEALL, G.N.; SOLOMON, D.H.","year":"1966","unstructured":"BEALL, G.N. & SOLOMON, D.H. (1966b) On the immunological nature of the long acting thyroid stimulator. J. clin. Endocr. 26, 1382.","journal-title":"J. clin. Endocr"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1210\/jcem-20-1-81","article-title":"A sensitive method for the detection of iodinated compounds in human plasma and its application to the study of thyrotoxicosis","volume":"20","author":"BIRD, R.; FARRAN, H.E.A.","year":"1960","unstructured":"BIRD, R. & FARRAN, H.E.A. (1960) A sensitive method for the detection of iodinated compounds in human plasma and its application to the study of thyrotoxicosis. J. clin. Endocr. 20, 81.","journal-title":"J. clin. Endocr"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1172\/JCI104851","article-title":"Studies of the adrenal antigens and antibodies in Addison's Disease","volume":"42","author":"BLIZZARD, R.M.; KYLE, M.","year":"1963","unstructured":"BLIZZARD, R.M. & KYLE, M. (1963) Studies of the adrenal antigens and antibodies in Addison's Disease. J. clin. Invest. 42, 1653.","journal-title":"J. clin. Invest"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1001\/archneurpsyc.1957.02330420072015","article-title":"Depressive affect and endocrine functions","volume":"78","author":"BOARD, F.W.A.D.E.S.O.N.; R.; PERSKY, H.","year":"1957","unstructured":"BOARD, F. WADESON, R. & PERSKY, H. (1957) Depressive affect and endocrine functions. Arch. Neurol. Psychiat. 78, 612.","journal-title":"Arch. Neurol. Psychiat"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0022-3999(63)90006-0","article-title":"Stress, personality and thyroid disease","volume":"7","author":"BROWN, L.B.; HETZEL, B.S.","year":"1963","unstructured":"BROWN, L.B. & HETZEL, B.S. (1963) Stress, personality and thyroid disease. J. psychosom. Res. 7, 223.","journal-title":"J. psychosom. Res"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1113\/jphysiol.1954.sp005189","article-title":"The effect of emotional and physical stress on thyroid activation in the rabbit","volume":"126","author":"GRANT, B.R.O.W.N.; K., HARR1s; W., G.; REICHLIN, S.","year":"1954","unstructured":"BROWN GRANT, K., HARR1s, G.W. & REICHLIN, S. (1954) The effect of emotional and physical stress on thyroid activation in the rabbit. J. Physiol. (Lond.), 126, 29.","journal-title":"J. Physiol. (Lond.)"},{"key":"ref_17","article-title":"Relation between long acting thyroid stimulator and thyroid function in thyrotoxicosis","volume":"878","author":"CARNEIRO, L.; DORRINGTON, K.J.; MUNRo., D.S.","year":"1966","unstructured":"CARNEIRO, L., DORRINGTON, K.J. & MUNRo., D.S. (1966a) Relation between long acting thyroid stimulator and thyroid function in thyrotoxicosis. Lancet, ii, 878.","journal-title":"Lancet"},{"key":"ref_18","first-page":"215","article-title":"Recovery of long acting thyroid stimulator from serum of patients with thyrotoxicosis by concentration of imunoglobulin G","volume":"31","author":"CARNEIRO, L.; DORRINGTON, K.J.; MuNRo, D.S.","year":"1966","unstructured":"CARNEIRO, L., DORRINGTON, K.J. & MuNRo, D.S. (1966b) Recovery of long acting thyroid stimulator from serum of patients with thyrotoxicosis by concentration of imunoglobulin G. Clin. Sci. 31, 215.","journal-title":"Clin. Sci"},{"key":"ref_19","article-title":"The relationship of thyrotoxicosis and carcinoma of the thyroid to endemic goitre","volume":"894","author":"CLEMENTS, F.W.","year":"1954","unstructured":"CLEMENTS, F.W. (1954) The relationship of thyrotoxicosis and carcinoma of the thyroid to endemic goitre. Med. J. Aust. ii, 894.","journal-title":"Med. J. Aust"},{"key":"ref_20","author":"CLEMENTS, F.W.","year":"1960","unstructured":"CLEMENTS, F.W. (1960) Endemic Goitre. W.H.O. Monograph, Geneva."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0065-2776(08)60710-5","article-title":"Structure and biological activity of immunoglobulins","volume":"4","author":"COHEN, S.; PORTER, R.B.","year":"1964","unstructured":"COHEN, S. & PORTER, R.B. (1964) Structure and biological activity of immunoglobulins. Advanc. Immunol. 4, 287.","journal-title":"Advanc. Immunol"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1097\/00005053-193405000-00002","article-title":"The psychiatric study of hyperthyroid patients","volume":"79","author":"CONRAD, A.","year":"1934","unstructured":"CONRAD, A. (1934) The psychiatric study of hyperthyroid patients. J. nerv. ment. Dis. 79, 505.","journal-title":"J. nerv. ment. Dis"},{"key":"ref_23","series-title":"Proceedings 5th International Thyroid Conference","first-page":"484","article-title":"The assay of exophthalmos producing substance (EPS) and the long acting thyroid stimulator (LATS) in whole and fractionated serum of patients with progressive exophthalmos. Current Topics in Thyroid Research","author":"DOBYNS, B.M.; RUDD, A.; LIEBE, D.","year":"1965","unstructured":"DOBYNS, B.M., RUDD, A. & LIEBE, D. (1965) The assay of exophthalmos producing substance (EPS) and the long acting thyroid stimulator (LATS) in whole and fractionated serum of patients with progressive exophthalmos. Current Topics in Thyroid Research. Proceedings 5th International Thyroid Conference (Ed. by C. Cassano and M. Andreoli), p. 484. Academic Press, New York."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1136\/bmj.1.5342.1374","article-title":"Auto-immune phenomena in pernicious anaemia","volume":"i,","author":"DONIACH, D.; RoIrr, I.; TAYLOR, K.B.","year":"1963","unstructured":"DONIACH, D., RoIrr, I. & TAYLOR, K.B. (1963) Auto-immune phenomena in pernicious anaemia. Brit. med. J. i, 1374.","journal-title":"Brit. med. J"},{"key":"ref_25","series-title":"Proceedings 5th Inter, national Thyroid Conference","first-page":"455","article-title":"Chemical Studies on the long acting thyroid stimulator. Current Topics in Thyroid Research","author":"DORRINGTON, K.J.; CARNEIRO, L.; MuNRo, D.S.","year":"1965","unstructured":"DORRINGTON, K.J., CARNEIRO, L. & MuNRo, D.S. (1965) Chemical Studies on the long acting thyroid stimulator. Current Topics in Thyroid Research. Proceedings 5th Inter, national Thyroid Conference (Ed. by C. Cassano and M. Andreoli), p. 455. Academic Press, New York."},{"key":"ref_26","first-page":"165","article-title":"Immunological studies on the long acting thyroid stimulator","volume":"28","author":"DORRINGTON, K.J.; MUNRO, D.S.","year":"1965","unstructured":"DORRINGTON, K.J. & MUNRO, D.S. (1965) Immunological studies on the long acting thyroid stimulator. Clin. Sci. 28, 165.","journal-title":"Clin. Sci"},{"key":"ref_27","article-title":"Antibodies in the families of thyrotoxic patients","volume":"636","author":"EVANS, A.W.H.; WOODROW, J.C.; McDOUGALL, C.D.M.; CHEw, A.R.; EVANS, R.W.","year":"1967","unstructured":"EVANS, A.W.H., WOODROW, J.C., McDOUGALL, C.D.M., CHEw, A.R. & EVANS, R.W. (1967) Antibodies in the families of thyrotoxic patients. Lancet, i, 636.","journal-title":"Lancet"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1210\/endo-75-1-42","article-title":"Effect of emotional stress and TSH on thyroid vein hormone level in sheep with exteriorized thyroids","volume":"75","author":"FALCONER, I.R.; HETZEL, B.S.","year":"1964","unstructured":"FALCONER, I.R. & HETZEL, B.S. (1964) Effect of emotional stress and TSH on thyroid vein hormone level in sheep with exteriorized thyroids. Endocrinology, 75, 42.","journal-title":"Endocrinology"},{"key":"ref_29","article-title":"Iodinated tyrosines in the plasma of patients with thyrotoxicosis","volume":"793","author":"FARRAN, H.E.A.; LEA, H.J.; GOOLDEN, A.W.G.; ABBOTr, J.D.","year":"1959","unstructured":"FARRAN, H.E.A., LEA, H.J., GOOLDEN, A.W.G. & ABBOTr, J.D. (1959) Iodinated tyrosines in the plasma of patients with thyrotoxicosis. Lancet, i, 793.","journal-title":"Lancet"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/0006-3002(62)90104-X","article-title":"Fractionation of human serum fractions by gel filtration","volume":"63","author":"FLODIN, P.; KILLANDER, J.","year":"1962","unstructured":"FLODIN, P. & KILLANDER, J. (1962) Fractionation of human serum fractions by gel filtration. Biochim. biophys. Acta (Amst.), 63, 403.","journal-title":"Biochim. biophys. Acta (Amst.)"},{"issue":"69","key":"ref_31","article-title":"Globulin synthesis by human peripheral lymphoctyes","volume":"65","author":"FORBES, I.J.; HENDERSON, D.W.","year":"1966","unstructured":"FORBES, I.J. & HENDERSON, D.W. (1966) Globulin synthesis by human peripheral lymphoctyes. Ann. intern. Med. 65,69.","journal-title":"Ann. intern. Med"},{"key":"ref_32","first-page":"304","article-title":"Synthesis of protein by human lymphocytes in vitro","volume":"14","author":"FORBES, I.J.; TURNER, K.J.","year":"1965","unstructured":"FORBES, I.J. & TURNER, K.J. (1965) Synthesis of protein by human lymphocytes in vitro. I. Clinical studies. Aust. Ann. Med. 14, 304.","journal-title":"I. Clinical studies. Aust. Ann. Med"},{"key":"ref_33","first-page":"143","article-title":"Studies of the effects of salicylate in hyperthyroidism","volume":"15","author":"GOOD, B.F.; HETZEL, B.S.; HOFFMAN, M.J.; WELLBY, M.L.; BLACK, M.L.; POTrER, H.A.; BUTTFIELD, J.H.","year":"1966","unstructured":"GOOD, B.F., HETZEL, B.S., HOFFMAN, M.J., WELLBY, M.L., BLACK, M.L., POTrER, H.A. & BUTTFIELD, J.H. (1966) Studies of the effects of salicylate in hyperthyroidism. Aust. Ann. Med. 15, 143.","journal-title":"Aust. Ann. Med"},{"key":"ref_34","article-title":"Increases in deaths due to exophthalmic goitre, 1925-1951","volume":"67","author":"GREENWALD, I.","year":"1962","unstructured":"GREENWALD, I. (1962) Increases in deaths due to exophthalmic goitre, 1925-1951. Acta endocr. (Kbh.), Suppl. 67.","journal-title":"Acta endocr. (Kbh.)"},{"key":"ref_35","article-title":"The significance of the increased mortality from exophthalmic goitre in Australia after 1923","volume":"836","author":"GREENWALD, I.","year":"1965","unstructured":"GREENWALD, I. (1965) The significance of the increased mortality from exophthalmic goitre in Australia after 1923. Med. J. Aust. i, 836.","journal-title":"Med. J. Aust"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.0954-6820.1946.tb09240.x","article-title":"Thyrotoxicosis at Ulleval Hospital in the years 1934-1944 with a special view to frequency of the disease","volume":"125","author":"GRELLAND, R.","year":"1946","unstructured":"GRELLAND, R. (1946) Thyrotoxicosis at Ulleval Hospital in the years 1934-1944 with a special view to frequency of the disease. Acta med. scand. 125, 108.","journal-title":"Acta med. scand"},{"key":"ref_37","article-title":"The identification of 3-5-3' triiodothyronine in human plasma","volume":"439","author":"GROSS, J.; PITT-RIVERS, R.","year":"1952","unstructured":"GROSS, J. & PITT-RIVERS, R. (1952) The identification of 3-5-3' triiodothyronine in human plasma. Lancet, i, 439.","journal-title":"Lancet"},{"key":"ref_38","article-title":"The thymus in thyroid disease","volume":"776","author":"GuNN, A.; MICHIE, W.; IRVINE, W.J.","year":"1964","unstructured":"GuNN, A., MICHIE, W. & IRVINE, W.J. (1964) The thymus in thyroid disease. Lancet, ii, 776.","journal-title":"Lancet"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1113\/jphysiol.1958.sp006057","article-title":"The effect of electrical stimulation of the hypothalamus or pituitary gland on thyroid activity","volume":"143","author":"HARRIS, G.W.; WOODS, J.D.","year":"1958","unstructured":"HARRIS, G.W. & WOODS, J.D. (1958) The effect of electrical stimulation of the hypothalamus or pituitary gland on thyroid activity. J. Physiol. (Lond.), 143, 246.","journal-title":"J. Physiol. (Lond.)"},{"key":"ref_40","first-page":"150","article-title":"A catamnestic investigation of Danish twins","volume":"3","author":"HARVALD, B.; HAUGE, M.","year":"1956","unstructured":"HARVALD, B. & HAUGE, M. (1956) A catamnestic investigation of Danish twins. Dan. med. Bull. 3, 150.","journal-title":"Dan. med. Bull"},{"key":"ref_41","article-title":"Toxic diffuse goitre in monozygotic twins","volume":"306","author":"HASSAN, T.H.A.; GREIG, W.R.; BOYLE, J.A.; BOYLE, I.T.; WALLACE, T.J.","year":"1966","unstructured":"HASSAN, T.H.A., GREIG, W.R., BOYLE, J.A., BOYLE, I.T. & WALLACE, T.J. (1966) Toxic diffuse goitre in monozygotic twins. Lancet, ii, 306.","journal-title":"Lancet"},{"key":"ref_42","article-title":"Cannon revisited: Emotions and bodily changes-their relevance to disease","volume":"193","author":"HETZEL, B.S.","year":"1960","unstructured":"HETZEL, B.S. (1960) Cannon revisited: Emotions and bodily changes-their relevance to disease. Med. J. Aust. i, 193.","journal-title":"Med. J. Aust"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1038\/icb.1958.51","article-title":"Alteration of metabolic response to adrenaline in man by pretreatment with triiodothyronine and hydrocortisone","volume":"36","author":"HETZEL, B.S.; CHARNOCK, J.S.; GILMORE, H.; LEMERCIER, K.","year":"1958","unstructured":"HETZEL, B.S., CHARNOCK, J.S., GILMORE, H. & LEMERCIER, K. (1958) Alteration of metabolic response to adrenaline in man by pretreatment with triiodothyronine and hydrocortisone. Aust. J. exp. Biol. med. Sci. 36, 479.","journal-title":"Aust. J. exp. Biol. med. Sci"},{"key":"ref_44","article-title":"Salicylate induced fall in plasma PBI in hyperthyroidism","volume":"957","author":"HETZEL, B.S.; GOOD, B.F.; WELLBY, M.L.; CHARNOCK, J.S.","year":"1960","unstructured":"HETZEL, B.S., GOOD, B.F., WELLBY, M.L. & CHARNOCK, J.S. (1960) Salicylate induced fall in plasma PBI in hyperthyroidism. Lancet, i, 957.","journal-title":"Lancet"},{"key":"ref_45","article-title":"Clinical experience with serum LATS in relation to exophthalmos after therapy for thyrotoxicosis","author":"HETZEL, B.S.; MASON, E.K.; WANG, K.H.","year":"1968","unstructured":"HETZEL, B.S., MASON, E.K. & WANG, K.H. (1968) Clinical experience with serum LATS in relation to exophthalmos after therapy for thyrotoxicosis. Aust. Ann. Med. (In press).","journal-title":"Aust. Ann. Med"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0022-3999(56)90021-6","article-title":"Changes in urinary nitrogen and electrolyte excretion during stressful life experiences and their relation to thyroid function","volume":"1","author":"HETZEL, B.S.; SCHOTTSTAEDT, W.W.; GRACE, W.J.; WOLFF, H.G.","year":"1956","unstructured":"HETZEL, B.S., SCHOTTSTAEDT, W.W., GRACE, W.J. & WOLFF, H.G. (1956) Changes in urinary nitrogen and electrolyte excretion during stressful life experiences and their relation to thyroid function. J. psychosom. Res. 1, 177.","journal-title":"J. psychosom. Res"},{"key":"ref_47","first-page":"204","article-title":"The clinical significance of plasma thyroid stimulating activity in hyperthyroidism","volume":"15","author":"HOFFMANN, M.J.; HETZEL, B.S.","year":"1966","unstructured":"HOFFMANN, M.J. & HETZEL, B.S. (1966) The clinical significance of plasma thyroid stimulating activity in hyperthyroidism. Aust. Ann. Med. 15, 204.","journal-title":"Aust. Ann. Med"},{"key":"ref_48","first-page":"262","article-title":"Neonatal thyrotoxicosis: Report of three cases involving four infants","volume":"15","author":"HOFFMANN, M.J.; HETZEL, B.S.; MANSON, J.","year":"1966","unstructured":"HOFFMANN, M.J., HETZEL, B.S. & MANSON, J. (1966) Neonatal thyrotoxicosis: Report of three cases involving four infants. Aust. Ann. Med. 15, 262.","journal-title":"Aust. Ann. Med"},{"key":"ref_49","first-page":"98","article-title":"Studies of the nature of plasma thyroid stimulating activity in hyperthyroidism","volume":"16","author":"HOFFMANN, M.J.; MASON, E.K.; GOOD, B.F.; HETZEL, B.S.; FERGUSON, K.","year":"1967","unstructured":"HOFFMANN, M.J., MASON, E.K., GOOD, B.F., HETZEL, B.S. & FERGUSON, K. (1967) Studies of the nature of plasma thyroid stimulating activity in hyperthyroidism. Aust. Ann. Med. 16, 98.","journal-title":"Aust. Ann. Med"},{"key":"ref_50","first-page":"714","article-title":"Abnormalities of iodine metabolism in euthyroid relatives of patients with Graves'","volume":"35","author":"INGBAR, S.H.; FREINKEL, N.; DOWLING, J.T.; KUMAGAI, L.F.","year":"1956","unstructured":"INGBAR, S.H., FREINKEL, N., DOWLING, J.T. & KUMAGAI, L.F. (1956) Abnormalities of iodine metabolism in euthyroid relatives of patients with Graves' disease. J. clin. Invest. 35, 714.","journal-title":"disease. J. clin. Invest"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1113\/expphysiol.1964.sp001738","article-title":"Thyroid autoimmunity as a disorder of immunological tolerance","volume":"49","author":"IRVINE, W.J.","year":"1964","unstructured":"IRVINE, W.J. (1964) Thyroid autoimmunity as a disorder of immunological tolerance. Quart. J. exp. Physiol. 49, 324.","journal-title":"Quart. J. exp. Physiol"},{"key":"ref_52","article-title":"Thyrotoxicosis and Hashimoto's goitre in a pair of monozygotic twins with serum long acting thyroid stimulator","volume":"15","author":"JAYSON, M.I.V.; DONIACH, D.; BENHAMOU-GLYNN, N.; RoiTT, I.M.; ELKABIR, D.J.","year":"1967","unstructured":"JAYSON, M.I.V., DONIACH, D., BENHAMOU-GLYNN, N., RoiTT, I.M. & ELKABIR, D.J. (1967) Thyrotoxicosis and Hashimoto's goitre in a pair of monozygotic twins with serum long acting thyroid stimulator. Lancet, ii, 15.","journal-title":"Lancet"},{"key":"ref_53","article-title":"Clinical significance of the rheumatoid serum factor","volume":"523","author":"KELLGREN, J.H.; BALL, J.","year":"1959","unstructured":"KELLGREN, J.H. & BALL, J. (1959) Clinical significance of the rheumatoid serum factor. Brit. med. J. i, 523.","journal-title":"Brit. med. J"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1471-0528.1952.tb04112.x","article-title":"Obstetrics and gynaecology in relation to thyrotoxicosis and myasthenia gravis","volume":"59","author":"KEYNES, G.","year":"1952","unstructured":"KEYNES, G. (1952) Obstetrics and gynaecology in relation to thyrotoxicosis and myasthenia gravis. J. Obstet. Gynaec. Brit. Emp. 59, 173.","journal-title":"J. Obstet. Gynaec. Brit. Emp"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1210\/jcem-24-10-1005","article-title":"Isolation and identification of the long acting thyroid stimulator and its relation to hyperthyroidism and circumscribed pretibial myxoedema","volume":"24","author":"KRISS, J.P.; PLESHAKOV, V.; CHIEN, J.R.","year":"1964","unstructured":"KRISS, J.P., PLESHAKOV, V. & CHIEN, J.R. (1964) Isolation and identification of the long acting thyroid stimulator and its relation to hyperthyroidism and circumscribed pretibial myxoedema. J. clin. Endocr. 24, 1005.","journal-title":"J. clin. Endocr"},{"key":"ref_56","series-title":"Current Topics in Thyroid Research. Proceedings 5th International Thyroid Conference; S.) and the alteration of its activity by enzymatic digestion and partial chemical degradation","first-page":"433","article-title":"Studies on the formation of long acting thyroid stimulator globulin","author":"KRISS, J.P.; PLESHAKOV, V.; ROSENBLUM, A.; CHIEN, J.R.","year":"1965","unstructured":"KRISS, J.P., PLESHAKOV, V., ROSENBLUM, A. & CHIEN, J.R. (1965) Studies on the formation of long acting thyroid stimulator globulin (L.A.T.S.) and the alteration of its activity by enzymatic digestion and partial chemical degradation. Current Topics in Thyroid Research. Proceedings 5th International Thyroid Conference (Ed. by C. Cassano and M. Andreoli), p. 433. Academic Press, New York."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1530\/acta.0.0190091","article-title":"The serum protein pattern in disorders of thyroid function","volume":"19","author":"LAMBERG, B.A.; GRASBECK, R.","year":"1955","unstructured":"LAMBERG, B.A. & GRASBECK, R. (1955) The serum protein pattern in disorders of thyroid function. Acta. endocr. (Kbh.), 19, 91.","journal-title":"Acta. endocr. (Kbh.)"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/0002-9343(65)90104-X","article-title":"Graves Disease without hyperthyroidism","volume":"39","author":"LIDDLE, G.W.; HEYSSEL, R.M.; McKENZIE, J.M.","year":"1965","unstructured":"LIDDLE, G.W., HEYSSEL, R.M. & McKENZIE, J.M. (1965) Graves Disease without hyperthyroidism. Amer. J. Med. 39, 845.","journal-title":"Amer. J. Med"},{"key":"ref_59","article-title":"Iodine and the Incidence of Goiter","author":"MCCLENDON, J.","year":"1939","unstructured":"MCCLENDON, J. (1939) Iodine and the Incidence of Goiter. University of Minnesota Press, Minneapolis."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1097\/00000658-193411000-00004","article-title":"Thyroid surgery as affected by the generalized use of iodized salt in an endemic goitre regionpreventive surgery","volume":"100","author":"MCCLURE, R.D.","year":"1934","unstructured":"MCCLURE, R.D. (1934) Thyroid surgery as affected by the generalized use of iodized salt in an endemic goitre regionpreventive surgery. Ann. Surg. 100, 924.","journal-title":"Ann. Surg"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1677\/joe.0.0320029","article-title":"A comparison of the heat stability of long-acting thyroid stimulator and human thyroid-stimulating hormone","volume":"32","author":"MCGIVEN, A.R.; ADAMS, D.D.; PURVES, H.D.","year":"1965","unstructured":"MCGIVEN, A.R., ADAMS, D.D. & PURVES, H.D. (1965) A comparison of the heat stability of long-acting thyroid stimulator and human thyroid-stimulating hormone. J. Endocr. 32, 29.","journal-title":"J. Endocr"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1210\/endo-62-6-865","article-title":"Delayed thyroid response to serum from thyrotoxic patients","volume":"62","author":"McKENZIE, J.M.","year":"1958","unstructured":"McKENZIE, J.M. (1958) Delayed thyroid response to serum from thyrotoxic patients. Endocrinology, 62, 865.","journal-title":"Endocrinology"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1210\/jcem-21-6-635","article-title":"Studies on the thyroid activator of hyperthyroidism","volume":"21","author":"McKENZIE, J.M.","year":"1961","unstructured":"McKENZIE, J.M. (1961) Studies on the thyroid activator of hyperthyroidism. J. clin. Endocr. 21, 635.","journal-title":"J. clin. Endocr"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"3571","DOI":"10.1016\/S0021-9258(19)70859-X","article-title":"Fractionation of plasma containing the long acting thyroid stimulator","volume":"237","author":"McKENZIE, J.M.","year":"1962","unstructured":"McKENZIE, J.M. (1962) Fractionation of plasma containing the long acting thyroid stimulator. J. biol. Chem. 237, 3571.","journal-title":"J. biol. Chem"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1210\/jcem-24-7-660","article-title":"Neonatal Graves Disease","volume":"24","author":"McKENZIE, J.M.","year":"1964","unstructured":"McKENZIE, J.M. (1964) Neonatal Graves Disease. J. clin. Endocr. 24, 660.","journal-title":"J. clin. Endocr"},{"key":"ref_66","first-page":"1","article-title":"The long acting thyroid stimulator","volume":"1","author":"McKENZIE, J.M.","year":"1967","unstructured":"McKENZIE, J.M. (1967) The long acting thyroid stimulator. Recent Progr. Horm. Res. 1, 1.","journal-title":"Recent Progr. Horm. Res"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"126","DOI":"10.3181\/00379727-105-26032","article-title":"Effect of antiserum on bioassay of thyrotropin and thyroid activator of hyperthyroidism","volume":"105","author":"McKENZIE, J.M.; FISHMAN, J.","year":"1960","unstructured":"McKENZIE, J.M. & FISHMAN, J. (1960) Effect of antiserum on bioassay of thyrotropin and thyroid activator of hyperthyroidism. Proc. Soc. exp. Biol. (N. Y.), 105, 126.","journal-title":"Proc. Soc. exp. Biol. (N. Y.)"},{"key":"ref_68","series-title":"Proceedings 5th International Thyroid Conference","first-page":"445","article-title":"The origin of the long acting thyroid stimulator. Current Topics in Thyroid Research'","author":"McKENZIE, J.M.; GORDON, J.","year":"1965","unstructured":"McKENZIE, J.M. & GORDON, J. (1965) The origin of the long acting thyroid stimulator. Current Topics in Thyroid Research' Proceedings 5th International Thyroid Conference (Ed. by C. Cassano and M. Andreoli), p. 445, Academic Press, New York."},{"key":"ref_69","article-title":"Autoimmune Diseases","author":"MACKAY, I.R.; BURNET, F.M.","year":"1963","unstructured":"MACKAY, I.R. & BURNET, F.M. (1963) Autoimmune Diseases. Thomas, Springfield, Illinois."},{"key":"ref_70","article-title":"The metabolism of thyroid hormones","author":"MACLAGAN, H.F.; BOWDEN, C.H.; WILKINSON, J.H.","year":"1957","unstructured":"MACLAGAN, H.F., BOWDEN, C.H. & WILKINSON, J.H. (1957) The metabolism of thyroid hormones."},{"key":"ref_71","first-page":"5","article-title":"Detection and determination of thyroxine and triiodothyronine in human plasma","volume":"67","author":"MCNICOL, G.P.","year":"1961","unstructured":"Detection and determination of thyroxine and triiodothyronine in human plasma. Biochem. J. 67, 5. MCNICOL, G.P. (1961) Thyrotoxicosis associated with pernicious anaemia. Amer. J. med. Sci. 241, 336.","journal-title":"Biochem. J; Thyrotoxicosis associated with pernicious anaemia"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1001\/jama.1935.92760250003009","article-title":"The physiology and principal interrelations of the thyroid","volume":"104","author":"MARINE, D.","year":"1935","unstructured":"MARINE, D. (1935) The physiology and principal interrelations of the thyroid. J. Amer. med. Ass. 104, 2250.","journal-title":"J. Amer. med. Ass"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"875","DOI":"10.7326\/0003-4819-41-5-875","article-title":"Endemic goitre: A problem in preventive medicine","volume":"41","author":"MARINE, D.","year":"1954","unstructured":"MARINE, D. (1954) Endemic goitre: A problem in preventive medicine. Ann. intern. Med. 41, 875.","journal-title":"Ann. intern. Med"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1097\/00000441-193410000-00022","article-title":"The exophthalmos of Graves' Disease-its experimental production and significance","volume":"188","author":"MARINE, D.; ROSEN, S.H.","year":"1934","unstructured":"MARINE, D. & ROSEN, S.H. (1934) The exophthalmos of Graves' Disease-its experimental production and significance. Amer. J. med. Sci. 188, 565.","journal-title":"Amer. J. med. Sci"},{"key":"ref_75","first-page":"207","article-title":"The hereditary and familial aspect of exophthalmic goitre and nodular goitre","volume":"14","author":"MARTIN, L.; FiSHER, R.A.","year":"1945","unstructured":"MARTIN, L. & FiSHER, R.A. (1945) The hereditary and familial aspect of exophthalmic goitre and nodular goitre. Quart. J. Med. 14, 207.","journal-title":"Quart. J. Med"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1210\/jcem-27-11-1529","article-title":"An improved bioassay for long acting thyroid stimulator (LATS)","volume":"27","author":"MASON, E.K.H.E.T.Z.E.L.; S., B.; GOOD, B.F.; STENHOUSE, N.S.","year":"1967","unstructured":"MASON, E.K. HETZEL, B.S., GOOD, B.F. & STENHOUSE, N.S. (1967) An improved bioassay for long acting thyroid stimulator (LATS). J. clin. Endocr. 27, 1529.","journal-title":"J. clin. Endocr"},{"key":"ref_77","article-title":"The Thyroid and its Diseases","author":"MEANS, J.H.","year":"1937","unstructured":"MEANS, J.H. (1937) The Thyroid and its Diseases. Lippincott, Philadelphia."},{"key":"ref_78","article-title":"The Thyroid and its Diseases","author":"MEANS, J.H.; GROOT, D.E.; J., L.; STANBURY, J.B.","year":"1963","unstructured":"MEANS, J.H., DE GROOT, L.J. & STANBURY, J.B. (1963) The Thyroid and its Diseases, 3rd edn. Blakiston Division, McGraw-Hill, New York.","edition":"3rd edn"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/j.0954-6820.1945.tb06893.x","article-title":"Increasing incidence of hyperthyroidism in Denmark","volume":"121","author":"MEULENGRACHT, E.","year":"1945","unstructured":"MEULENGRACHT, E. (1945) Increasing incidence of hyperthyroidism in Denmark. Acta med. scand. 121, 446.","journal-title":"Acta med. scand"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1001\/archinte.1949.00220310002001","article-title":"Epidemiologic aspects of thyrotoxicosis","volume":"83","author":"MEULENGRACHT, E.","year":"1949","unstructured":"MEULENGRACHT, E. (1949) Epidemiologic aspects of thyrotoxicosis. Arch. intern. Med. 83, 119.","journal-title":"Arch. intern. Med"},{"key":"ref_81","first-page":"706","article-title":"Autoantibodies and autoimmune diseases","volume":"181","author":"MILGROM, F.; WITEBSKY, E.","year":"1962","unstructured":"MILGROM, F. & WITEBSKY, E. (1962) Autoantibodies and autoimmune diseases. J. Amer. med. Ass. 181, 706.","journal-title":"J. Amer. med. Ass"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1210\/jcem-26-5-504","article-title":"Concentration of long acting thyroid stimulator (LATS) by subfractionation of gamma G globulin from Graves'","volume":"26","author":"MIYAI, K.; WERNER, S.C.","year":"1966","unstructured":"MIYAI, K. & WERNER, S.C. (1966) Concentration of long acting thyroid stimulator (LATS) by subfractionation of gamma G globulin from Graves' Disease serum. J. clin. Endocr. 26, 504.","journal-title":"Disease serum. J. clin. Endocr"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1677\/joe.0.0190064","article-title":"Observations on the discharge of radioiodine from the thyroid glands of mice injected with human sera","volume":"19","author":"MUNRO, D.S.","year":"1959","unstructured":"MUNRO, D.S. (1959) Observations on the discharge of radioiodine from the thyroid glands of mice injected with human sera. J. Endocr. 19, 64.","journal-title":"J. Endocr"},{"key":"ref_84","series-title":"Proceedings of the Association of Physicians of Great Britain and","first-page":"631","volume":"29","author":"MUNRO, D.S.; MAJOR, P.W.; WILSON, G.M.","year":"1960","unstructured":"MUNRO, D.S., MAJOR, P.W. & WILSON, G.M. (1960) Proceedings of the Association of Physicians of Great Britain and Ireland. Quart. J. Med. 29, 631."},{"key":"ref_85","article-title":"Biochemical and clinical studies in familial goitre due to an iodotyrosine deiodinase defect","author":"NIALL, H.D.; WELLBY, M.L.; HETZEL, B.S.; HUDSON, B.; CHENOWETH, R.A.","year":"1968","unstructured":"NIALL, H.D., WELLBY, M.L., HETZEL, B.S., HUDSON, B. & CHENOWETH, R.A. (1968) Biochemical and clinical studies in familial goitre due to an iodotyrosine deiodinase defect. Aust. Ann. Med. (In press).","journal-title":"Aust. Ann. Med"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1210\/jcem-24-2-160","article-title":"Clinical studies on long acting thyroid stimulator","volume":"24","author":"NOGUCHI, A.; KURIHARA, H.; SATO, S.","year":"1964","unstructured":"NOGUCHI, A., KURIHARA, H. & SATO, S. (1964) Clinical studies on long acting thyroid stimulator. J. clin. Endocr. 24, 160.","journal-title":"J. clin. Endocr"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1210\/jcem-25-9-1179","article-title":"Radioimmunoassay of thyrotropin in human serum","volume":"25","author":"ODELL, W.D.; WILBER, J.F.; PAUL, W.E.","year":"1965","unstructured":"ODELL, W.D., WILBER, J.F. & PAUL, W.E. (1965) Radioimmunoassay of thyrotropin in human serum. J. clin. Endocr. 25, 1179.","journal-title":"J. clin. Endocr"},{"key":"ref_88","first-page":"478","article-title":"Classic descriptions of disease","volume":"1","author":"PARRY, C.H.","year":"1825","unstructured":"PARRY, C.H. (1825) Quoted by MAJOR, R.A. (1948) Classic descriptions of disease. Collected Works, Vol. 1, p. 478.","journal-title":"Collected Works"},{"key":"ref_89","first-page":"12","article-title":"Medical surgical experience with goiter in endemic district","author":"PERINETTI, H.","year":"1952","unstructured":"PERINETTI, H. (1952) Medical surgical experience with goiter in endemic district. Trans. Amer. Ass. Goiter, p. 12.","journal-title":"Trans. Amer. Ass. Goiter"},{"key":"ref_90","first-page":"217","article-title":"Technique of endemic goiter surveys","volume":"18","author":"PEREZ, C.; SCRIMSHAW, S.W.; MUNEZ, J.A.","year":"1948","unstructured":"PEREZ, C., SCRIMSHAW, S.W. & MUNEZ, J.A. (1948) Technique of endemic goiter surveys. Bull. Wld Hlth Org. 18, 217.","journal-title":"Bull. Wld Hlth Org"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1210\/jcem-23-4-336","article-title":"Parallel assays of thyrotrophin, long acting thyroid stimulator and exophthalmos producing substance in some endocrine disorders","volume":"23","author":"PIMSTONE, B.L.; HOFFENBERG, R.; BLACK, E.","year":"1963","unstructured":"PIMSTONE, B.L., HOFFENBERG, R. & BLACK, E. (1963) Parallel assays of thyrotrophin, long acting thyroid stimulator and exophthalmos producing substance in some endocrine disorders. J. clin. Endocr. 23, 336.","journal-title":"J. clin. Endocr"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1210\/jcem-25-2-189","article-title":"Thyrotropin and long acting thyroid stimulator assays in thyroid disease","volume":"25","author":"PINCHERA, A.; PINCHERA, M.G.; STANBURY, J.B.","year":"1965","unstructured":"PINCHERA, A., PINCHERA, M.G. & STANBURY, J.B. (1965) Thyrotropin and long acting thyroid stimulator assays in thyroid disease. J. clin. Endocr. 25, 189.","journal-title":"J. clin. Endocr"},{"key":"ref_93","first-page":"171","article-title":"Exophthalmic goitre in Olmsted County, Minnesota","volume":"46","author":"PLUMMER, H.S.","year":"1931","unstructured":"PLUMMER, H.S. (1931) Exophthalmic goitre in Olmsted County, Minnesota. Trans. Asso. Amer. Phycns, 46, 171.","journal-title":"Trans. Asso. Amer. Phycns"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/oxfordjournals.bmb.a069811","article-title":"Thyroid stimulating hormone","volume":"16","author":"PURVES, H.D.; ADAMS, D.D.","year":"1960","unstructured":"PURVES, H.D. & ADAMS, D.D. (1960) Thyroid stimulating hormone. Brit. med. Bull. 16, 128.","journal-title":"Brit. med. Bull"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1210\/endo-71-3-456","article-title":"Effect of electrical stimulation of the limbic system on pituitary thyroidal function","volume":"71","author":"SHIZUME, K.; MATSUZAKI, F.; IION, S.; MATSUDA, K.; NAGATAKI, S.; OKINAKA, S.","year":"1962","unstructured":"SHIZUME, K., MATSUZAKI, F., IION, S., MATSUDA, K., NAGATAKI, S. & OKINAKA, S. (1962) Effect of electrical stimulation of the limbic system on pituitary thyroidal function. Endocrinology, 71, 456.","journal-title":"Endocrinology"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1210\/jcem-15-10-1216","article-title":"The occurrence of monoand diiodotyrosine in the blood of a patient with congenital goitre","volume":"15","author":"STANBURY, J.B.; KASSENAAR, A.A.H.; MEIJER, J.W.A.; TERPSTRA, J.","year":"1955","unstructured":"STANBURY, J.B., KASSENAAR, A.A.H., MEIJER, J.W.A. & TERPSTRA, J. (1955) The occurrence of monoand diiodotyrosine in the blood of a patient with congenital goitre. J. clin. Endocr. 15, 1216.","journal-title":"J. clin. Endocr"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1210\/jcem-24-11-1129","article-title":"Glucocorticoid induced disappearance of long acting thyroid stimulator in the ophthalmopathy of Graves'","volume":"24","author":"SNYDER, N.J.; GREEN, D.E.; SOLOMON, D.H.","year":"1964","unstructured":"SNYDER, N.J., GREEN, D.E. & SOLOMON, D.H. (1964) Glucocorticoid induced disappearance of long acting thyroid stimulator in the ophthalmopathy of Graves' Disease. J. clin. Endocr. 24, 1129.","journal-title":"Disease. J. clin. Endocr"},{"key":"ref_98","first-page":"134","article-title":"Studies on the diurnal variation and response to emotional stress of the thyroid gland","volume":"6","author":"TINGLEY, T.O.; MORIuSS, W.O.; HILL, S.R.","year":"1958","unstructured":"TINGLEY, T.O., MORIuSS, W.O. & HILL, S.R. (1958) Studies on the diurnal variation and response to emotional stress of the thyroid gland. Clin. Res. 6, 134.","journal-title":"Clin. Res"},{"key":"ref_99","first-page":"826","article-title":"Synthesis of proteins by human leukocytes in vitro","volume":"96","author":"TURNER, K.J.; FORBES, I.J.","year":"1966","unstructured":"TURNER, K.J. & FORBES, I.J. (1966) Synthesis of proteins by human leukocytes in vitro. J. Immunol. 96, 826.","journal-title":"J. Immunol"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"553","DOI":"10.7326\/0003-4819-2-6-553","article-title":"The constitutional entity of exophthalmic goiter and so-called toxic adenoma","volume":"2","author":"WARTHIN, A.S.","year":"1928","unstructured":"WARTHIN, A.S. (1928) The constitutional entity of exophthalmic goiter and so-called toxic adenoma. Ann. intern. Med. 2, 553.","journal-title":"Ann. intern. Med"},{"key":"ref_101","first-page":"152","article-title":"Demonstration of iodotyrosines in human plasma in response to thyroid stimulation","volume":"193","author":"WELLBY, M.L.; HETZEL, B.S.","year":"1962","unstructured":"WELLBY, M.L. & HETZEL, B.S. (1962) Demonstration of iodotyrosines in human plasma in response to thyroid stimulation. Nature (Lond.), 193, 152.","journal-title":"Nature (Lond.)"},{"key":"ref_102","article-title":"The circulating thyroid hormones in thyrotoxicosis","volume":"439","author":"WELLBY, M.L.; HETZEL, B.S.; GOOD, B.F.","year":"1963","unstructured":"WELLBY, M.L., HETZEL, B.S. & GOOD, B.F. (1963a) The circulating thyroid hormones in thyrotoxicosis. Brit. med. J. i, 439.","journal-title":"Brit. med. J"},{"key":"ref_103","first-page":"30","article-title":"The effect of thyrotropic hormone on the plasma thyroid hormones in man","volume":"12","author":"WELLBY, M.L.; HETZEL, B.S.; ISAACHSEN, M.L.","year":"1963","unstructured":"WELLBY, M.L., HETZEL, B.S. & ISAACHSEN, M.L. (1963b) The effect of thyrotropic hormone on the plasma thyroid hormones in man. Aust. Ann. Med. 12, 30.","journal-title":"Aust. Ann. Med"},{"key":"ref_104","article-title":"The Thyroid","author":"WERNER, S.C.","year":"1955","unstructured":"WERNER, S.C. (1955) The Thyroid. Hoeber-Harper, New York."},{"key":"ref_105","first-page":"132","article-title":"Graves' Disease and total thyroidectomy","volume":"276","author":"WERNER, S.C.F.E.I.N.D.; R., C.; AMA, M.","year":"1967","unstructured":"WERNER, S.C. FEIND, C.R. & AMA, M. (1967) Graves' Disease and total thyroidectomy. New Engl. J. Med. 276, 132.","journal-title":"New Engl. J. Med"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1038\/185472a0","article-title":"Neutralization of human serum and pituitary thyrotropic fractions with antisera to bovine pituitary thyrotropin","volume":"185","author":"WERNER, S.C.; OTERO-RIVIZ, E.; SEGAL, B.C.; BATES, R.W.","year":"1960","unstructured":"WERNER, S.C., OTERO-RIVIZ, E., SEGAL, B.C. & BATES, R.W. (1960) Neutralization of human serum and pituitary thyrotropic fractions with antisera to bovine pituitary thyrotropin. Nature (Lond.), 185, 472.","journal-title":"Nature (Lond.)"},{"key":"ref_107","article-title":"Remission of hyperthyroidism (Graves' Disease) and altered pattern of serum thyroxine binding induced by prednisone","volume":"751","author":"WERNER, S.C.; PLATMAN, S.R.","year":"1965","unstructured":"WERNER, S.C. & PLATMAN, S.R. (1965) Remission of hyperthyroidism (Graves' Disease) and altered pattern of serum thyroxine binding induced by prednisone. Lancet, ii, 751.","journal-title":"Lancet"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/44\/511\/363\/50474575\/postgradmedj-44-363.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/44\/511\/363\/50474575\/postgradmedj-44-363.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T09:28:46Z","timestamp":1685438926000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/44\/511\/363\/7051866"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1968,5,1]]},"references-count":107,"journal-issue":{"issue":"511","published-online":{"date-parts":[[1968,5,1]]},"published-print":{"date-parts":[[1968,5,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.44.511.363","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1968,5]]},"published":{"date-parts":[[1968,5,1]]}}}