{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T13:17:44Z","timestamp":1703683064461},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"526","license":[{"start":{"date-parts":[[1969,8,1]],"date-time":"1969-08-01T00:00:00Z","timestamp":-13219200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1969,8,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Some aspects of blood fluidity in hypoperfusion with particular reference to the important role of the red cell are discussed. Changes in different organ beds and the internal fluidity of the red cell, which is of obvious importance in capillary flow are not considered.<\/jats:p>\n               <jats:p>It is not certain to what extent the phenomena discussed are critical factors in morbidity and mortality in shock because of paucity of objective data but there are good reasons for assuming them to be of importance and for directing treatment towards their correction.<\/jats:p>\n               <jats:p>The properties of Dextran 40 applicable to the therapy of disordered blood fluidity are described.<\/jats:p>","DOI":"10.1136\/pgmj.45.526.530","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:27:15Z","timestamp":1230582435000},"page":"530-533","source":"Crossref","is-referenced-by-count":8,"title":["The microcirculation in shock"],"prefix":"10.1093","volume":"45","author":[{"given":"N A","family":"Matheson","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Aberdeen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1969,8,1]]},"reference":[{"key":"ref_1","first-page":"1059","article-title":"Comparison of hemodynamic responses to whole blood and plasma expanders in clinical traumatic shock","volume":"121","author":"CAREY, J.S.; BROWN, R.S.; WOODWARD, N.W.; YAO, S.T.; SHOEMAKER, W.C.","year":"1965","unstructured":"CAREY, J.S., BROWN, R.S., WOODWARD, N.W., YAO, S.T. & SHOEMAKER, W.C. (1965) Comparison of hemodynamic responses to whole blood and plasma expanders in clinical traumatic shock. Surg. Gynec. Obstet. 121, 1059.","journal-title":"Surg. Gynec. Obstet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1126\/science.157.3790.829","article-title":"Blood viscosity: Influence of erythrocyte aggregation","volume":"157","author":"CHIEN, S.; USAMI, S.; DELLENBACK, R.J.; GREGERSEN, M.I.; NANNINGA, L.B.; GUEST, M.M.","year":"1967","unstructured":"CHIEN, S., USAMI, S., DELLENBACK, R.J., GREGERSEN, M.I., NANNINGA, L.B. & GUEST, M.M. (1967) Blood viscosity: Influence of erythrocyte aggregation. Science, 157, 829.","journal-title":"Science"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1122\/1.548959","article-title":"Rheology of human blood measurement near and at zero shear rate","volume":"7","author":"COKELET, G.R.; MERRILL, E.W.; GILLILAND, E.R.; SHIN, H.","year":"1963","unstructured":"COKELET, G.R., MERRILL, E.W., GILLILAND, E.R. & SHIN, H. (1963) Rheology of human blood measurement near and at zero shear rate. Trans. Soc. Rheol. 7, 303.","journal-title":"Trans. Soc. Rheol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1152\/ajplegacy.1957.192.1.171","article-title":"Effect of varying the hematocrit ratio on the susceptibility to hemorrhagic shock","volume":"192","author":"CROWELL, J.W.; BOUNDS, S.H.; JOHNSON, W.W.","year":"1958","unstructured":"CROWELL, J.W., BOUNDS, S.H. & JOHNSON, W.W. (1958) Effect of varying the hematocrit ratio on the susceptibility to hemorrhagic shock. Amer. J. 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(1969) Measurement of red cell dispersion in surgical patients. European Surg. Res. In press.","journal-title":"European Surg. Res"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/S0140-6736(66)91138-X","article-title":"Effect of Dextran 40 on erythrocyte aggregation","volume":"i,","author":"ENGESET, J.; STALKER, A.L.; MATHESON, N.A.","year":"1966","unstructured":"ENGESET, J., STALKER, A.L. & MATHESON, N.A. (1966) Effect of Dextran 40 on erythrocyte aggregation. Lancet, i, 1124.","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1093\/cvr\/1.4.379","article-title":"Effects of Dextran 40 on red cell aggregation in rabbits","volume":"1","author":"ENGESET, J.; STALKER, A.L.; MATHESON, N.A.","year":"1967","unstructured":"ENGESET, J., STALKER, A.L. & MATHESON, N.A. (1967a) Effects of Dextran 40 on red cell aggregation in rabbits. Cardiovasc. Res. 1, 379.","journal-title":"Cardiovasc. 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(1963) Effect of hemorrhagic shock on the reactivity of resistance and capacitance vessels and on capillary filtration transfer in cat skeletal muscle. Circulat. Res. 13, 105.","journal-title":"Circulat. Res"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/00000658-196201000-00004","article-title":"Blood sludging: an experimental critique of its occurrence and its supposed effects","volume":"155","author":"PORIES, W.J.; HARRIS, P.D.; HINSHAW, J.R.; DAVIS, T.P.; SCHWARTZ, S.I.","year":"1962","unstructured":"PORIES, W.J., HARRIS, P.D., HINSHAW, J.R., DAVIS, T.P. & SCHWARTZ, S.I. (1962) Blood sludging: an experimental critique of its occurrence and its supposed effects. Ann. Surg. 155, 33.","journal-title":"Ann. Surg"},{"key":"ref_17","author":"REPLOGLE, R.L.; MEISELMAN, H.J.; MERRILL, E.","year":"1967","unstructured":"REPLOGLE, R.L., MEISELMAN, H.J. & MERRILL, E.W. (1967)"},{"key":"ref_18","article-title":"A microcirculatory study of the effects of Dextran","author":"STALKER, A.L.","year":"1961","unstructured":"STALKER, A.L. (1961) A microcirculatory study of the effects of Dextran. M.D. Thesis, University of Aberdeen."},{"key":"ref_19","first-page":"108","article-title":"Intravascular erythrocyte aggregation","volume":"4","author":"STALKER, A.L.","year":"1964","unstructured":"STALKER, A.L. (1964) Intravascular erythrocyte aggregation. Bibl. anat. (Basel), 4, 108.","journal-title":"Bibl. anat. (Basel)"},{"key":"ref_20","article-title":"Adaption to acute severe hemodilution with Dextran 75 in dogs","author":"TAKAORI, M.; SAFAR, P.","year":"1966","unstructured":"TAKAORI, M. & SAFAR, P. (1966) Adaption to acute severe hemodilution with Dextran 75 in dogs. Arch. Surg.","journal-title":"Arch. 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Academic Press, New York."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/45\/526\/530\/50476115\/postgradmedj-45-530.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/45\/526\/530\/50476115\/postgradmedj-45-530.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T10:18:12Z","timestamp":1685441892000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/45\/526\/530\/7051812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,8,1]]},"references-count":23,"journal-issue":{"issue":"526","published-online":{"date-parts":[[1969,8,1]]},"published-print":{"date-parts":[[1969,8,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.45.526.530","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1969,8]]},"published":{"date-parts":[[1969,8,1]]}}}