{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:25:10Z","timestamp":1760783110605},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"564","license":[{"start":{"date-parts":[[1972,10,1]],"date-time":"1972-10-01T00:00:00Z","timestamp":86745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1972,10,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Carcinoma of the parathyroid gland is rare, constituting about 1% of most series of patients with hyperparathyroidism. In 1969 a collective review identified forty-six unequivocal cases, and since then a further seven cases have been described in the literature.<\/jats:p>\n               <jats:p>A brief review of the condition is presented, and one further case of hyperfunctioning adenocarcinoma of the parathyroid gland is reported in detail. Primary treatment is discussed, together with postoperative biochemical problems, and the therapeutic manoeuvres available to deal with recurrences are presented.<\/jats:p>","DOI":"10.1136\/pgmj.48.564.626","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:27:15Z","timestamp":1230582435000},"page":"626-631","source":"Crossref","is-referenced-by-count":8,"title":["Hyperfunctioning carcinoma of the parathyroid gland"],"prefix":"10.1093","volume":"48","author":[{"given":"T C","family":"Gale","sequence":"first","affiliation":[{"name":"Whittington Hospital , Highgate Hill, London, N.19"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C W I","family":"Owens","sequence":"additional","affiliation":[{"name":"Whittington Hospital , Highgate Hill, London, N.19"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1972,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1177\/003591576806111P128","article-title":"Psychiatric aspects of primary hyperparathyroidism","volume":"61","author":"ANDERSON, J.","year":"1968","unstructured":"ANDERSON, J. (1968) Psychiatric aspects of primary hyperparathyroidism. Proceedings of the Royal Society of Medicine, 61, 1123.","journal-title":"Proceedings of the Royal Society of Medicine"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1210\/jcem-17-12-1407","article-title":"Magnesium studies in relation to hyperparathyroidism","volume":"17","year":"1957","unstructured":"BARNES, B.A., KRANE, S.M. & COPE, 0. (1957) Magnesium studies in relation to hyperparathyroidism. Journal of Clinical Endocrinology, 17, 1407.","journal-title":"Journal of Clinical Endocrinology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/S0039-6109(16)37047-5","article-title":"Carcinoma of the parathyroid gland: Report of a case","volume":"43","author":"BEAHRS, O.H.; ANGELOS, P.S.; WOOLNER, L.B.","year":"1963","unstructured":"BEAHRS, O.H., ANGELOS, P.S. & WOOLNER, L.B. (1963) Carcinoma of the parathyroid gland: Report of a case. 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Armed Forces Institute of Pathology, Washington D.C."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1056\/NEJM196605262742105","article-title":"The story of hyperparathyroidism at the Massachusetts General Hospital","volume":"274","author":"COPE, 0","year":"1966","unstructured":"COPE, 0. (1966) The story of hyperparathyroidism at the Massachusetts General Hospital. New England Jouirnal of Medicine, 274, 1174.","journal-title":"New England Jouirnal of Medicine"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1097\/00000658-195310000-00018","article-title":"Carcinoma of the parathyroid gland: Four cases among 143 patients with hyperparathyroidism","volume":"138","author":"COPE, O.; NARDI, G.L.; CASTLEMAN, B.","year":"1953","unstructured":"COPE, O., NARDI, G.L. & CASTLEMAN, B. (1953) Carcinoma of the parathyroid gland: Four cases among 143 patients with hyperparathyroidism. 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(1970) The ultra-structure of parathyroid glands removed from patients with primary hyperparathyroidism: A report of forty cases, including four carcinomata. Journal of Pathology, 102, 189.","journal-title":"Journal of Pathology"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1136\/pgmj.44.511.411","article-title":"Calcitonin: A review of experimental and clinical investigations","volume":"44","author":"FOSTER, G.V.","year":"1968","unstructured":"FOSTER, G.V. (1968) Calcitonin: A review of experimental and clinical investigations. Postgraduate Medical Journal, 44, 411.","journal-title":"Postgraduate Medical Journal"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1097\/00000658-196611000-00021","article-title":"Metastic parathyroid carcinoma and hormonal chemotherapy","volume":"164","author":"GOEPFERT, H.; SMART, C.R.; RoCHLIN, D.B.","year":"1966","unstructured":"GOEPFERT, H., SMART, C.R. & RoCHLIN, D.B. 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(1970) Discussion (vide Saunders, 1970). Proceedings of the Royal Society of Medicine, 63, 454.","journal-title":"Proceedings of the Royal Society of Medicine"},{"key":"ref_24","first-page":"378","article-title":"Adenocarcinoma of the parathyroid gland: Review of the literature and report of a case","volume":"33","author":"MANSOUR, K.A.; LETTON, A.H.","year":"1967","unstructured":"MANSOUR, K.A. & LETTON, A.H. (1967) Adenocarcinoma of the parathyroid gland: Review of the literature and report of a case. American Surgeon, 33, 378.","journal-title":"American Surgeon"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"219","DOI":"10.5694\/j.1326-5377.1968.tb82736.x","article-title":"Hyperfunctioning parathyroid carcinoma","volume":"2","author":"NEWTON, N.C.; SUMICH, M.G.","year":"1968","unstructured":"NEWTON, N.C. & SUMICH, M.G. (1968a) Hyperfunctioning parathyroid carcinoma. 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(1969) Results of parathyroidectomy."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1002\/bjs.1800560206","volume":"56","unstructured":"British Journal of SurgerY, 56, 106.","journal-title":"British Journal of SurgerY"},{"key":"ref_29","first-page":"1657","article-title":"Treatment with thyrocalcitonin of the hypercalcaemia of parathyroid carcinoma","volume":"1","author":"& BARTTER, F. C.","year":"1968","unstructured":"PAK, C.Y.C., 'WILLS, M.R., SMITH, G.W. I1 & BARTTER, F.C. (1968) Treatment with thyrocalcitonin of the hypercalcaemia of parathyroid carcinoma. Journal of Clinical Endocrinology, 28, 1657.","journal-title":"Journal of Clinical Endocrinology"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1210\/jcem-28-10-1491","article-title":"Psychiatric disorders in primary hyperparathyroidism","volume":"28","author":"PETERSEN, P.","year":"1968","unstructured":"PETERSEN, P. 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