{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:17:55Z","timestamp":1756995475871},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"578","license":[{"start":{"date-parts":[[1973,12,1]],"date-time":"1973-12-01T00:00:00Z","timestamp":123552000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1973,12,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>There are as yet few clinical reports of successful treatment of bacterial endocarditis with oral antibiotics, or of the use of the rifamycins in non-tuberculous infections. A case of refractory staphylococcal endocarditis successfully treated with oral rifampicin and erythromycin is presented. The availability of effective oral antibiotic therapy avoids the serious difficulties of long term parenteral antibiotics and offers a hopeful alternative to emergency cardiac surgery in this condition.<\/jats:p>","DOI":"10.1136\/pgmj.49.578.920","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:31:39Z","timestamp":1230582699000},"page":"920-922","source":"Crossref","is-referenced-by-count":5,"title":["Oral antibiotic cure of staphylococcal endocarditis"],"prefix":"10.1093","volume":"49","author":[{"given":"N D","family":"Burman","sequence":"first","affiliation":[{"name":"University of Cape Town"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H S","family":"Joffe","sequence":"additional","affiliation":[{"name":"University of Cape Town"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Watson","sequence":"additional","affiliation":[{"name":"University of Cape Town"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1973,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1136\/bmj.3.5713.24","article-title":"Rifampicin-induced immune thrombocytopenia","volume":"3","author":"BLAJCHMAN, M.A.; LOWRY, R.C.; PETTIT, J.E.; STRADLING, P.","year":"1970","unstructured":"BLAJCHMAN, M.A., LOWRY, R.C., PETTIT, J.E. & STRADLING, P. (1970) Rifampicin-induced immune thrombocytopenia. British Medical Journal, 3, 24.","journal-title":"British Medical Journal"},{"key":"ref_2","first-page":"339","article-title":"Bacterial endocarditis: current concepts","volume":"124","author":"CARPENTER, C.C.J.; WALLACE, C.K.","year":"1969","unstructured":"CARPENTER, C.C.J. & WALLACE, C.K. (1969) Bacterial endocarditis: current concepts. Bulletin of the Johns Hopkins Hospital, 124, 339.","journal-title":"Bulletin of the Johns Hopkins Hospital"},{"key":"ref_3","first-page":"697","article-title":"A comparative trial with combinations of rifampicin, ethambutol and isoniazid (hydronsan) in previously untreated cases of pulmonary tuberculosis","volume":"45","author":"DORMER, B.A.; SALINGER, P.L.","year":"1971","unstructured":"DORMER, B.A. & SALINGER, P.L. (1971) A comparative trial with combinations of rifampicin, ethambutol and isoniazid (hydronsan) in previously untreated cases of pulmonary tuberculosis. South African Medical Journal, 45, 697.","journal-title":"South African Medical Journal"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1136\/bmj.1.5583.5","article-title":"Emergency valve replacement in infective endocarditis","volume":"1","author":"E.D.I.T.O.R.I.A.L.","year":"1968","unstructured":"EDITORIAL (1968) Emergency valve replacement in infective endocarditis. British Medical Journal, 1, 5.","journal-title":"British Medical Journal"},{"key":"ref_5","first-page":"1551","article-title":"Bacterial endocarditis occurring after open heart surgery","volume":"96","author":"FRASER, R.S.; ROSSALL, R.E.; DVORKIN, J.","year":"1967","unstructured":"FRASER, R.S., ROSSALL, R.E. & DVORKIN, J. (1967) Bacterial endocarditis occurring after open heart surgery. Canadian Medical Association Journal, 96, 1551.","journal-title":"Canadian Medical Association Journal"},{"key":"ref_6","first-page":"17","article-title":"Staphylococcal endocarditis; results of combined antibiotic therapy in fourteen consecutive cases (1956-1959)","volume":"32","author":"JAWITZ, E.; BRAINERD, H.D.","year":"1962","unstructured":"JAWITZ, E. & BRAINERD, H.D. (1962) Staphylococcal endocarditis; results of combined antibiotic therapy in fourteen consecutive cases (1956-1959). American Journal of Medicine, 32, 17.","journal-title":"American Journal of Medicine"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1136\/bmj.4.5732.410","article-title":"Combined rifampicin and erythromycin for bacterial endocarditis","volume":"4","author":"PEARD, M.C.; FLECK, D.G.; GARROD, L.P.; WATERWORTH, P.M.","year":"1970","unstructured":"PEARD, M.C., FLECK, D.G., GARROD, L.P. & WATERWORTH, P. M. (1970) Combined rifampicin and erythromycin for bacterial endocarditis. British Medical Journal, 4, 410.","journal-title":"British Medical Journal"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/49\/578\/920\/50253745\/postgradmedj-49-920.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/49\/578\/920\/50253745\/postgradmedj-49-920.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T08:57:00Z","timestamp":1684227420000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/49\/578\/920\/7064829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,12,1]]},"references-count":7,"journal-issue":{"issue":"578","published-online":{"date-parts":[[1973,12,1]]},"published-print":{"date-parts":[[1973,12,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.49.578.920","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1973,12]]},"published":{"date-parts":[[1973,12,1]]}}}