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At very high pressure this autoregulation is overwhelmed and cerebral blood flow increases, and at very low pressures autoregulation fails and blood flow diminishes","author":"Wood, J.B.; Hospital, County","year":"1973","unstructured":"The autoregulation of the cerebral circulation results in a constant cerebral blood flow despite wide fluctuations in arterial pressure. At very high pressure this autoregulation is overwhelmed and cerebral blood flow increases, and at very low pressures autoregulation fails and blood flow diminishes (Strandgaard et al., 1973). In arterial hypertension, autoregulation persists, but functions over a higher range of blood pressures than normal. In a group of severely hypertensive patients, Strandgaard et al. (1973) showed that autoregulation broke down when the mean arterial pressure fell abruptly to 120 mmHg, Requests for reprints: Dr J. B. Wood, County Hospital, Hereford HR1 2ER.","journal-title":"et al; In arterial hypertension, autoregulation persists, but functions over a higher range of blood pressures than normal. In a group of severely hypertensive patients, Strandgaard"},{"key":"ref_14","article-title":"and dizziness due to cerebral hypoxia occurred when the mean arterial pressure fell to about 70 mmHg, in contrast to normotensive subjects who could tolerate much lower pressures. Vigorous treatment of hypertension may, therefore, lead to cerebral hypoxia if the blood pressure falls too far","year":"1966","unstructured":"and dizziness due to cerebral hypoxia occurred when the mean arterial pressure fell to about 70 mmHg, in contrast to normotensive subjects who could tolerate much lower pressures. Vigorous treatment of hypertension may, therefore, lead to cerebral hypoxia if the blood pressure falls too far. 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