{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:30:51Z","timestamp":1725841851356},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"604","license":[{"start":{"date-parts":[[1976,2,1]],"date-time":"1976-02-01T00:00:00Z","timestamp":191980800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1976,2,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 42-year-old haemophiliac who presented with a cholestatic jaundice and repeated gastro-intestinal haemorrhage is described. The bleeding was initially thought to be due to the severity of the haemophilia itself rather than from any local cause and the jaundice thought to be due to a serum hepatitis. The correct diagnosis of ampullary carcinoma was eventually made after numerous barium studies, fibre-optic endoscopy and two laparotomies. A carcinoma was discovered at a second endoscopy some 12 months after initial presentation. Attention is brought to the rare association of ampullary carcinoma and haemophilia, and to the difficulties involved in diagnosis.<\/jats:p>","DOI":"10.1136\/pgmj.52.604.92","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:31:39Z","timestamp":1230582699000},"page":"92-95","source":"Crossref","is-referenced-by-count":11,"title":["Carcinoma of the ampulla of Vater in a haemophiliac patient"],"prefix":"10.1093","volume":"52","author":[{"given":"J","family":"Catford","sequence":"first","affiliation":[{"name":"Departments of Gastroenterology, Radiology, and Haematology, Westminster Hospital , London, S. W. 1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Zeegen","sequence":"additional","affiliation":[{"name":"Departments of Gastroenterology, Radiology, and Haematology, Westminster Hospital , London, S. W. 1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I M","family":"Prosser","sequence":"additional","affiliation":[{"name":"Departments of Gastroenterology, Radiology, and Haematology, Westminster Hospital , London, S. W. 1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Naik","sequence":"additional","affiliation":[{"name":"Departments of Gastroenterology, Radiology, and Haematology, Westminster Hospital , London, S. W. 1"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1976,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1365-2141.1974.tb00476.x","article-title":"Jaundice and antibodies directed against factors VII and IX in patients treated for haemophilia or Christmas disease in the United Kingdom","volume":"26","author":"BIGGS, R.","year":"1974","unstructured":"BIGGS, R. (1974) Jaundice and antibodies directed against factors VII and IX in patients treated for haemophilia or Christmas disease in the United Kingdom. British Journal of Haematology; 26, 313.","journal-title":"British Journal of Haematology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1136\/bmj.2.5865.505","article-title":"Early endoscopy of oesophagus, stomach and duodenal bulb in patients with haematemesis and melaena","volume":"2","author":"COTTON, P.B.; ROSENBERG, M.T.; WALDRAM, R.P.L.; AXON, A.T.R.","year":"1973","unstructured":"COTTON, P.B., ROSENBERG, M.T., WALDRAM, R.P.L. & AXON, A.T.R. (1973) Early endoscopy of oesophagus, stomach and duodenal bulb in patients with haematemesis and melaena. British Medical Journal, 2, 505.","journal-title":"British Medical Journal"},{"key":"ref_3","first-page":"503","article-title":"Gastrointestinal bleeding in haemophilia","volume":"XLII,","author":"FORBES, C.D.; BARR, R.D.; PRENTICE, C.R.M.; DOUGLAS, A.S.","year":"1973","unstructured":"FORBES, C.D., BARR, R.D., PRENTICE, C.R.M. & DOUGLAS, A.S. (1973) Gastrointestinal bleeding in haemophilia. Quarterly Journal of Medicine, N.S., XLII, 503.","journal-title":"Quarterly Journal of Medicine, N. S"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2214\/ajr.107.1.119","article-title":"Tubeless hypotonic duodenography: Technique value and limitations","volume":"107","author":"MARTEL, W.; SCHOLTENS, P.A.; LIM, L.W.","year":"1969","unstructured":"MARTEL, W., SCHOLTENS, P.A. & LIM, L.W. (1969) Tubeless hypotonic duodenography: Technique value and limitations. American Journal of Roentgenology, 107, 119.","journal-title":"American Journal of Roentgenology"},{"key":"ref_5","article-title":"Diseases of the Liver and Biliary System","author":"SHERLOCK, S.","year":"1968","unstructured":"SHERLOCK, S. (1968) Diseases of the Liver and Biliary System, 4th edition, 758-766. Blackwell Scientific Publications, Oxford.","edition":"4th edition"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1136\/bmj.2.5530.1624","article-title":"Haemorrhagic episodes in haemophilia-a 5 year prospective study","volume":"2","author":"STUART, J.; DAVIES, S.H.; CUMMING, R.A.; GIRDWOOD, R.H.; DARG, A.","year":"1966","unstructured":"STUART, J., DAVIES, S.H., CUMMING, R.A., GIRDWOOD, R.H. & DARG, A. (1966) Haemorrhagic episodes in haemophilia-a 5 year prospective study. British Medical Journal, 2, 1624.","journal-title":"British Medical Journal"},{"key":"ref_7","first-page":"947","article-title":"Haemophilia syndromes. A survey of 267 patients","volume":"ii,","author":"WILKINSON, J.F.; NOUR-ELDIN, F.; ISRAELS, M.C.G.; BARRETT, K.E.","year":"1961","unstructured":"WILKINSON, J.F., NOUR-ELDIN, F., ISRAELS, M.C.G. & BARRETT, K.E. (1961) Haemophilia syndromes. A survey of 267 patients. Lancet, ii, 947.","journal-title":"Lancet"},{"key":"ref_8","first-page":"95","article-title":"Postgradutate Medical Journal","volume":"52","year":"1976","unstructured":"Postgradutate Medical Journal (February 1976) 52, 95-101."},{"key":"ref_9","article-title":"Introduction Hyperparathyroidism is one of the hormonal conditions that may be an aetiological factor in pancreatitis. However, the precise frequency with which pancreatitis occurs in association with hyperparathyroidism is not known. Mixter, Keynes and Cope","volume-title":"found sixty-two cases of these diseases co-existing and reported that pancreatitis occurred in eleven out of 155 patients with hyperparathyroidism. It appears that either the coexistence of these two diseases is not as common in the United Kingdom as in the United States of America, or that pancreatitis is not investigated so thoroughly to exclude hyperparathyroidism","year":"1962","unstructured":"Introduction Hyperparathyroidism is one of the hormonal conditions that may be an aetiological factor in pancreatitis. However, the precise frequency with which pancreatitis occurs in association with hyperparathyroidism is not known. Mixter, Keynes and Cope (1962) found sixty-two cases of these diseases co-existing and reported that pancreatitis occurred in eleven out of 155 patients with hyperparathyroidism. It appears that either the coexistence of these two diseases is not as common in the United Kingdom as in the United States of America, or that pancreatitis is not investigated so thoroughly to exclude hyperparathyroidism."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/52\/604\/92\/50184745\/postgradmedj-52-92.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/52\/604\/92\/50184745\/postgradmedj-52-92.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T12:45:26Z","timestamp":1683290726000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/52\/604\/92\/7037814"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,2,1]]},"references-count":9,"journal-issue":{"issue":"604","published-online":{"date-parts":[[1976,2,1]]},"published-print":{"date-parts":[[1976,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.52.604.92","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1976,2]]},"published":{"date-parts":[[1976,2,1]]}}}