{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T07:10:30Z","timestamp":1683529830948},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"609","license":[{"start":{"date-parts":[[1976,7,1]],"date-time":"1976-07-01T00:00:00Z","timestamp":205027200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1976,7,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Two unusual complications are described in a patient who had chronic lymphatic leukaemia. Spontaneous rupture of the spleen occurred and was related to subcapsular infarction and haemorrhage. The possibility of this complication should always be considered when signs of an acute abdomen develop in a patient with leukaemia. The phenomenon of pseudo-hyperkalaemia was demonstrated. This was most likely due to increased leucocyte fragility in vitro.<\/jats:p>","DOI":"10.1136\/pgmj.52.609.470","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:31:39Z","timestamp":1230582699000},"page":"470-472","source":"Crossref","is-referenced-by-count":0,"title":["Spontaneous splenic rupture and pseudo-hyperkalaemia in chronic lymphatic leukaemia"],"prefix":"10.1093","volume":"52","author":[{"given":"Kenneth S","family":"Wilson","sequence":"first","affiliation":[{"name":"Department of Medicine, Royal Infirmary , Edinburgh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1976,7,1]]},"reference":[{"key":"ref_1","article-title":"Pseudo-hyperkalemia due to release of potassium from white blood cells during clotting","volume":"274","author":"BRONSON, W.R.; VITA, D.E.; T., V.; CARBONE, P.P.; COTLOVE, E.","year":"1966","unstructured":"BRONSON, W.R., DE VITA, V.T., CARBONE, P.P. & COTLOVE, E. (1966) Pseudo-hyperkalemia due to release of potassium from white blood cells during clotting. New England Journal of Medicine, 274, No. 7; 369.","journal-title":"New England Journal of Medicine"},{"key":"ref_2","first-page":"333","article-title":"Hamilton Bailey's Demonstrations of Physical Signs in Clinical Surgery","author":"CLAIN, A.","year":"1973","unstructured":"CLAIN, A. (1973) (Ed.) Hamilton Bailey's Demonstrations of Physical Signs in Clinical Surgery. 15th Edn, p.333. John Wright & Son Ltd, Bristol.","edition":"15th Edn"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1136\/bmj.1.4760.693","article-title":"Spontaneous rupture of a leukaemic spleen","volume":"1","author":"COORAY, G.H.","year":"1952","unstructured":"COORAY, G.H. (1952) Spontaneous rupture of a leukaemic spleen. British Medical Journal, 1, 693.","journal-title":"British Medical Journal"},{"key":"ref_4","article-title":"Extreme hyperkalaemia due to rapid lysis of leukaemic cells","volume":"27","author":"FENNELLY, J.J.; SMYTH, H.; MULDOWNEY, F.P.","year":"1974","unstructured":"FENNELLY, J.J., SMYTH, H. & MULDOWNEY, F.P. (1974) Extreme hyperkalaemia due to rapid lysis of leukaemic cells. Lancet, i, 27.","journal-title":"Lancet"},{"key":"ref_5","first-page":"950","article-title":"Spontaneous rupture of the spleen in chronic myeloid leukemia","volume":"40","author":"GREENFIELD, M.M.; LUND, H.","year":"1944","unstructured":"GREENFIELD, M.M. & LUND, H. (1944) Spontaneous rupture of the spleen in chronic myeloid leukemia. Ohio Stare Medical Journal, 40, 950.","journal-title":"Ohio Stare Medical Journal"},{"key":"ref_6","author":"HARTMANN, R.C.; AUDITORE, J.V.; JACKSON, D.P.","year":"1958","unstructured":"HARTMANN, R.C., AUDITORE, J.V. & JACKSON, D.P. (1958)"},{"key":"ref_7","first-page":"1356","article-title":"Hyperkalemia due to release of potassium from platelets during coagulation","volume":"37","author":"17,","year":"1964","unstructured":"Hyperkalemia due to release of potassium from platelets during coagulation. Journal cf Clinical Investigation, 37, 699. HYNES, H.E., SILVERSTEIN, M.N. & FAWCETT, K.J. (1964) Spontaneous rupture of the spleen in acute leukemia. Cancer, New York, Philadelphia, etc., 17, 1356.","journal-title":"Journal cf Clinical Investigation; Spontaneous rupture of the spleen in acute leukemia"},{"key":"ref_8","first-page":"212","article-title":"The Spleen","author":"MACPHERSON, A.I.S.; RICHMOND, J.; STUART, A.E.","year":"1972","unstructured":"MACPHERSON, A.I.S., RICHMOND, J. & STUART, A.E. (1972) The Spleen, p. 212. C. C. THOMAS, Springfield, Illinois."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1001\/archinte.1960.03820040017003","article-title":"Hyperkalemia associated with myeloproliferative disorder","volume":"106","author":"MYERSON, R.M.; FRUMIN, A.M.","year":"1960","unstructured":"MYERSON, R.M. & FRUMIN, A.M. (1960) Hyperkalemia associated with myeloproliferative disorder. Archives of Internal Medicine, 106, 479.","journal-title":"Archives of Internal Medicine"},{"key":"ref_10","first-page":"96","article-title":"Rupture of spleen in myelogenous leukemia. Medical Bulletin of the Veterans'","volume":"17","author":"NEAL, J.M.","year":"1940","unstructured":"NEAL, J.M. (1940) Rupture of spleen in myelogenous leukemia. Medical Bulletin of the Veterans' Administration, 17, 96.","journal-title":"Administration"},{"key":"ref_11","article-title":"Pseudohyperkalaemia in acute myeloid leukaemia","volume":"928","author":"RINGLEHANN, B.; LASZLO, E.; VAJDA, L.","year":"1974","unstructured":"RINGLEHANN, B., LASZLO, E. & VAJDA, L. (1974) Pseudohyperkalaemia in acute myeloid leukaemia. Lancet, i, 928.","journal-title":"Lancet"},{"key":"ref_12","first-page":"286","article-title":"Spontaneous rupture of spleen in chronic myeloid leukaemia","volume":"29","author":"SARIN, L.R.; SARIN, J.C.","year":"1957","unstructured":"SARIN, L.R. & SARIN, J.C. (1957) Spontaneous rupture of spleen in chronic myeloid leukaemia. Journal Indian Medical Association, 29, 286.","journal-title":"Journal Indian Medical Association"},{"issue":"1","key":"ref_13","article-title":"Splenic rupture in leukemia","volume":"267","author":"TARTAGLIA, A.P.; SCHARFMAN, W.B.; PROPP, S.","year":"1962","unstructured":"TARTAGLIA, A.P., SCHARFMAN, W.B. and PROPP, S. (1962). Splenic rupture in leukemia. New England Journal of Medicine, 267, No. 1, 31.","journal-title":"New England Journal of Medicine"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1136\/jcp.17.6.649","article-title":"Spurious hyperkalaemia","volume":"17","author":"WILLS, M.R.; FRASER, I.D.","year":"1964","unstructured":"WILLS, M.R. & FRASER, I.D. (1964). Spurious hyperkalaemia. Journal of Clinical Pathology, 17, 649.","journal-title":"Journal of Clinical Pathology"},{"key":"ref_15","first-page":"472","article-title":"Postgraduate Medical Journal","volume":"52","year":"1976","unstructured":"Postgraduate Medical Journal (July 1976) 52, 472-474."},{"key":"ref_16","article-title":"cytosis has been recorded with imipramine (Miller, 1963; Bird, 1960) and desipramine (Crammer and Elkes, 1967). There are no published reports of this complication following clomipramine, but three cases of clomipramine-induced agranulocytosis have been reported to the makers in the","volume-title":"personal communication). Intravenous clomipramine is used in the treatment of severe and resistant forms of depression. A case is now reported of severe agranulocytosis occurring in a patient who had received intravenous clomipramine for depression. The illness which followed was complicated by systemic Candida infection which was successfully treated with flucytosine","author":"Beaumont, U. K. (Dr G.","unstructured":"cytosis has been recorded with imipramine (Miller, 1963; Bird, 1960) and desipramine (Crammer and Elkes, 1967). There are no published reports of this complication following clomipramine, but three cases of clomipramine-induced agranulocytosis have been reported to the makers in the U.K. (Dr G. Beaumont, personal communication). Intravenous clomipramine is used in the treatment of severe and resistant forms of depression. A case is now reported of severe agranulocytosis occurring in a patient who had received intravenous clomipramine for depression. The illness which followed was complicated by systemic Candida infection which was successfully treated with flucytosine."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/52\/609\/470\/50184786\/postgradmedj-52-470.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/52\/609\/470\/50184786\/postgradmedj-52-470.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T06:37:16Z","timestamp":1683527836000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/52\/609\/470\/7037935"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,7,1]]},"references-count":16,"journal-issue":{"issue":"609","published-online":{"date-parts":[[1976,7,1]]},"published-print":{"date-parts":[[1976,7,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.52.609.470","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1976,7]]},"published":{"date-parts":[[1976,7,1]]}}}