{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:26:18Z","timestamp":1790198778200,"version":"4.1.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"612","license":[{"start":{"date-parts":[[1976,10,1]],"date-time":"1976-10-01T00:00:00Z","timestamp":212976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1976,10,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Corticosteroid therapy is of great value in many types of eye disease. The indications are briefly discussed, together with the choice of agent and mode of administration. The dangers of steroids are now widely recognized, and the complications are discussed, particularly cataract and glaucoma. Reference is also made to optic neuritis and thyroid ophthalmopathy, where the role of steroids is uncertain. Particular stress is laid on the need to keep steroid dosage as low as possible, so as to avoid systemic side effects. There are unfortunately many situations where treatment of doubtful efficacy has produced severe side effects. Despite the overall benefit of steroids in ophthalmology, there is a pressing need to find alternative treatment for a variety of blinding disorders.<\/jats:p>","DOI":"10.1136\/pgmj.52.612.634","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:31:39Z","timestamp":1230582699000},"page":"634-638","source":"Crossref","is-referenced-by-count":33,"title":["Steroids and the eye\u2014indications and complications"],"prefix":"10.1093","volume":"52","author":[{"given":"W J","family":"Dinning","sequence":"first","affiliation":[{"name":"Institute of Ophthalmology, University of London"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1976,10,1]]},"reference":[{"key":"ref_1","article-title":"Effects of corticosteroids on intraocular pressure and fluid dynamics","author":"ARMALY, M.F.","year":"1963","unstructured":"ARMALY, M.F. (1963) Effects of corticosteroids on intraocular pressure and fluid dynamics."},{"key":"ref_2","first-page":"32","article-title":"The effect of dexamethasone in the normal eye. Archives of Ophthalmology","volume":"70","author":"482. ARMALY, M. F","year":"1966","unstructured":"The effect of dexamethasone in the normal eye. Archives of Ophthalmology. Chicago, 70, 482. ARMALY, M.F. (1966) The heritable nature of dexamethasone-induced ocular hypertension. Archives of Ophthalmology. Chicago, 75, 32.","journal-title":"Chicago; The heritable nature of dexamethasone-induced ocular hypertension"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1136\/bjo.35.11.708","article-title":"Effect of cortisone on healing of wounds","volume":"35","author":"ASHTON, N.; COOK, C.","year":"1951","unstructured":"ASHTON, N. & COOK, C. (1951) Effect of cortisone on healing of wounds. 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Report on a therapeutic trial of cortisone and corticotrophin (ACTH) in exophthalmos and exophthalmic ophthalmoplegia by a Panel appointed by the Medical","volume":"6","author":"COUNCIL, M.E.D.I.C.A.L.R.E.S.E.A.R.C.H.","year":"1955","unstructured":"MEDICAL RESEARCH COUNCIL (1955) Cortisone in exophthalmos. Report on a therapeutic trial of cortisone and corticotrophin (ACTH) in exophthalmos and exophthalmic ophthalmoplegia by a Panel appointed by the Medical Research Council. Lancet, i, 6.","journal-title":"Research Council. Lancet"},{"key":"ref_21","first-page":"615","article-title":"Kortikosteroidbehandlung bei Neuritis nervi optici","volume-title":"Klinische","volume":"134","author":"NEUBAUER, H.; KARGES, E.","year":"1959","unstructured":"NEUBAUER, H. & KARGES, E. (1959) Kortikosteroidbehandlung bei Neuritis nervi optici. 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(1951) Use of adrenocorticotrophic hormone and cortisone in ocular disease. Archives of Ophthalmology. Chicago, 45, 299.","journal-title":"Archives of Ophthalmology. Chicago"},{"key":"ref_24","first-page":"227","article-title":"Treatment of retrobulbar neuritis with corticotrophin","volume":"ii,","author":"RAWSON, M.U.; LIVERSEDGE, L.A.","year":"1969","unstructured":"RAWSON, M.U. & LIVERSEDGE, L.A. (1969) Treatment of retrobulbar neuritis with corticotrophin. Lancet, ii, 227.","journal-title":"Lancet"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1001\/archopht.1959.04220040041006","article-title":"Treatment of herpes zoster ophthalmicus with corticotrophin and corticosteroids","volume":"62","author":"SCHEIE, H.G.; MCLELLAN, T.G.","year":"1959","unstructured":"SCHEIE, H.G. & MCLELLAN, T.G. (1959) Treatment of herpes zoster ophthalmicus with corticotrophin and corticosteroids. Archives of Ophthalmology. Chicago, 62, 579.","journal-title":"Archives of Ophthalmology. Chicago"},{"key":"ref_26","first-page":"64","article-title":"Cortisone and hydrocortisone in ocular infections","volume":"57","author":"THYGESON, P.; HOGAN, M.J.; KIMURA, S.J.","year":"1953","unstructured":"THYGESON, P., HOGAN, M.J. & KIMURA, S.J. (1953) Cortisone and hydrocortisone in ocular infections. Transactions of the American Academy of Ophthalmology and Otolaryngology, 57, 64.","journal-title":"Transactions of the American Academy of Ophthalmology and Otolaryngology"},{"key":"ref_27","first-page":"245","article-title":"The unfavorable effect of topical steroid therapy on herpetic keratitis","volume":"58","author":"THYGESON, P.; HOGAN, M.J.; KIMURA, S.J.","year":"1960","unstructured":"THYGESON, P., HOGAN, M.J. & KIMURA, S.J. (1960) The unfavorable effect of topical steroid therapy on herpetic keratitis. 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Mayo Clinic, 47, 969."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/52\/612\/634\/50185008\/postgradmedj-52-634.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/52\/612\/634\/50185008\/postgradmedj-52-634.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T06:37:46Z","timestamp":1683527866000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/52\/612\/634\/7038112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,10,1]]},"references-count":30,"journal-issue":{"issue":"612","published-online":{"date-parts":[[1976,10,1]]},"published-print":{"date-parts":[[1976,10,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.52.612.634","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1976,10]]},"published":{"date-parts":[[1976,10,1]]}}}