{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T06:40:34Z","timestamp":1684824034358},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"612","license":[{"start":{"date-parts":[[1976,10,1]],"date-time":"1976-10-01T00:00:00Z","timestamp":212976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1976,10,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>A further case of mesangiocapillary glomth reduced serum C3 levels is reported. The father of the patient was also found to have C3 deficiency. This lends support to the hypothesis that C3 deficiency may be the primary disorder relating these conditions and there is evidence in this case that the deficiency may be genetically determined. It is suggested that the complement state of close relatives, particularly younger siblings, of patients with these disorders should be investigated and, if abnormalities are found, they should be followed-up in order to elucidate the role of hypocomplementaemia in these uncommon disorders.<\/jats:p>","DOI":"10.1136\/pgmj.52.612.651","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:31:39Z","timestamp":1230582699000},"page":"651-652","source":"Crossref","is-referenced-by-count":2,"title":["The interrelationship between hypocomplementaemia, partial lipodystrophy and mesangiocapillary glomerulonephritis"],"prefix":"10.1093","volume":"52","author":[{"given":"Marion A","family":"Wakefield","sequence":"first","affiliation":[{"name":"Paediatric Department, Stoke Mandeville Hospital , Aylesbury, Buckinghamshire"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1976,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1056\/NEJM197303222881204","article-title":"Increased susceptibility to infection in a patient with type II essential hypercatabolism of C3","volume":"288","author":"ALPER, C.A.; BLOCH, K.J.; ROSEN, F.S.","year":"1973","unstructured":"ALPER, C.A., BLOCH, K.J. & ROSEN, F.S. (1973) Increased susceptibility to infection in a patient with type II essential hypercatabolism of C3. New England Journal of Medicine, 288, 601.","journal-title":"New England Journal of Medicine"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1172\/JCI105691","article-title":"Studies of the in vivo behavior of human C3 in normal subjects and patients","volume":"46","author":"ALPER, C.A.; ROSEN, F.S.","year":"1967","unstructured":"ALPER, C.A. & ROSEN, F.S. (1967) Studies of the in vivo behavior of human C3 in normal subjects and patients. Journal of Clinical Investigation, 46, 2021.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_3","first-page":"605","article-title":"Chronic renal disease in children with lipodystrophy","volume":"96","author":"GELLIS, S.S.; GREEN, S.; WALKER, D.","year":"1958","unstructured":"GELLIS, S.S., GREEN, S. & WALKER, D. (1958) Chronic renal disease in children with lipodystrophy. American Journal of Diseases of Children, 96, 605.","journal-title":"American Journal of Diseases of Children"},{"key":"ref_4","article-title":"Mesangiocapillary nephritis, partial lipodystrophy and hypocomplementaemia","volume":"535","year":"1973","unstructured":"PETERS, D.K., WILLIAMS, D.G., CHARLESWORTH, J.A., BOULTON-JONES, J.M., SISSONS, J.G.P., EVANS, D.J., KOURLINSKY, 0. & MOREL-MAROGER, L. (1973) Mesangiocapillary nephritis, partial lipodystrophy and hypocomplementaemia. Lancet, ii, 535.","journal-title":"Lancet"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1542\/peds.33.4.593","article-title":"The syndromes of total lipodystrophy and of partial lipodystrophy","volume":"33","author":"SENIOR, B.; GELLIS, S.S.","year":"1964","unstructured":"SENIOR, B. & GELLIS, S.S. (1964) The syndromes of total lipodystrophy and of partial lipodystrophy. Pediatrics, 33, 593.","journal-title":"Pediatrics"},{"key":"ref_6","article-title":"Partial lipodystrophy and hypocomplementaemic nephritis","volume":"679","author":"THOMPSON, R.A.; WHITE, R.H.R.","year":"1973","unstructured":"THOMPSON, R.A. & WHITE, R.H.R. (1973) Partial lipodystrophy and hypocomplementaemic nephritis. Lancet, ii, 679.","journal-title":"Lancet"},{"key":"ref_7","article-title":"The role of C3b in the breakdown of C3 in hypocomplementaemic mesangiocapillary glomerulonephritis","volume":"447","author":"WILLIAMS, D.G.; CHARLESWORTH, J.A.; LACHMANN, P.J.; PETERS, D.K.","year":"1973","unstructured":"WILLIAMS, D.G., CHARLESWORTH, J.A., LACHMANN, P.J. & PETERS, D.K. (1973) The role of C3b in the breakdown of C3 in hypocomplementaemic mesangiocapillary glomerulonephritis. Lancet, i, 447.","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1177\/003591577206500708","article-title":"Hypocomplementaemia, membranoproliferative glomerulonephritis and nephrotic syndrome associated with partial lipodystrophy of the face and trunk","volume":"65","author":"WILLIAMS, D.G.; SCOPES, J.W.; PETERS, D.K.","year":"1972","unstructured":"WILLIAMS, D.G., SCOPES, J.W. & PETERS, D.K. (1972) Hypocomplementaemia, membranoproliferative glomerulonephritis and nephrotic syndrome associated with partial lipodystrophy of the face and trunk. Proceedings of the Royal Society of Medicine, 65, 591.","journal-title":"Proceedings of the Royal Society of Medicine"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/52\/612\/651\/50184919\/postgradmedj-52-651.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/52\/612\/651\/50184919\/postgradmedj-52-651.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T06:20:47Z","timestamp":1684822847000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/52\/612\/651\/7038049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,10,1]]},"references-count":8,"journal-issue":{"issue":"612","published-online":{"date-parts":[[1976,10,1]]},"published-print":{"date-parts":[[1976,10,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.52.612.651","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1976,10]]},"published":{"date-parts":[[1976,10,1]]}}}