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The problems encountered in his management are discussed, including tracheostomy and genetic counselling.<\/jats:p>","DOI":"10.1136\/pgmj.52.613.723","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:31:39Z","timestamp":1230582699000},"page":"723-724","source":"Crossref","is-referenced-by-count":0,"title":["Familial anglo-oedema\u2014a particularly severe form"],"prefix":"10.1093","volume":"52","author":[{"given":"A R J","family":"Bosley","sequence":"first","affiliation":[{"name":"Royal Hampshire County Hospital , Winchester"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1976,11,1]]},"reference":[{"key":"ref_1","first-page":"317","article-title":"A family study of hereditary angioneurotic oedema","volume":"166","author":"BECK, P.; WILLS, D.; DAVIES, G.T.; LACHMAN, P.J.; SUSSMAN, M.","year":"1973","unstructured":"BECK, P., WILLS, D., DAVIES, G.T., LACHMAN, P.J. & SUSSMAN, M. (1973) A family study of hereditary angioneurotic oedema. Quiarterly Journal of Medicine, XLII, 166, 317.","journal-title":"Quiarterly Journal of Medicine, XLII"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/j.0954-6820.1972.tb04818.x","article-title":"Treatment of hereditary angio-oedema with tranexamic acid","volume":"192","author":"BLOHMt, G.","year":"1972","unstructured":"BLOHMt, G. (1972) Treatment of hereditary angio-oedema with tranexamic acid. Acta medica scandinavica, 192, 293.","journal-title":"Acta medica scandinavica"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1365-2133.1969.tb15938.x","article-title":"Hereditary angioneurotic oedema treated with epsilon aminocaproic acid","volume":"81","author":"CHAMPION, R.H.; LACHMANN, P.J.","year":"1969","unstructured":"CHAMPION, R.H. & LACHMANN, P.J. (1969) Hereditary angioneurotic oedema treated with epsilon aminocaproic acid. 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Federation Proceedings, 22, 613.","journal-title":"Federation Proceedings"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.0954-6820.1969.tb07345.x","article-title":"Extensive muscle necrosis after long-term treatment with aminocaproic acid in a case of hereditary periodic oedema","volume":"185","author":"E.","year":"1969","unstructured":"E. (1969) Extensive muscle necrosis after long-term treatment with aminocaproic acid in a case of hereditary periodic oedema. Acata medica scandinavica, 185, 341.","journal-title":"Acata medica scandinavica"},{"key":"ref_7","first-page":"330","article-title":"Hereditary angio-neurotic oedema. II. Deficiency of inhibitor of serum globlulin permeability factor and\/or plasma kallikrein","volume":"33","author":"LANDERMAN, N.S.; WEBSTER, N.E.; BECKER, E.K.; RATCLIFFE, H.E.","year":"1962","unstructured":"LANDERMAN, N.S., WEBSTER, N.E., BECKER, E.K. & RATCLIFFE, H.E. (1962) Hereditary angio-neurotic oedema. II. Deficiency of inhibitor of serum globlulin permeability factor and\/or plasma kallikrein. Journal ofAllergy, 33, 330.","journal-title":"Journal ofAllergy"},{"key":"ref_8","first-page":"1044","article-title":"Hereditary angio-neurotic oedema","volume":"i,","author":"ARTICLE, L.E.A.D.I.N.G.","year":"1973","unstructured":"LEADING ARTICLE (1973) Hereditary angio-neurotic oedema. Lancet, i, 1044.","journal-title":"Lancet"},{"key":"ref_9","first-page":"362","article-title":"Hereditary angioneurotic edema","volume":"95","author":"OSLER, W.","year":"1888","unstructured":"OSLER, W. (1888) Hereditary angioneurotic edema. American Journal of Medical Science, 95, 362.","journal-title":"American Journal of Medical Science"},{"key":"ref_10","article-title":"Replacement therapy in hereditary angio-neurotic oedema-successful treatment of two paitents with fresh frozen plasma","volume":"326","author":"PICKERING, R.J.; KELLY, J.R.; GOOD, R.A.; GEWURZ, H.","year":"1969","unstructured":"PICKERING, R.J., KELLY, J.R., GOOD, R.A & GEWURZ, H. (1969) Replacement therapy in hereditary angio-neurotic oedema-successful treatment of two paitents with fresh frozen plasma. Lancet, i, 326.","journal-title":"Lancet"},{"key":"ref_11","article-title":"Hereditary angio-neurotic oedema","volume":"41","author":"PICKERING, R.J.; KELLY, J.R.; GOOD, R.A.; GEWURZ, H.","year":"1973","unstructured":"PICKERING, R.J., KELLY, J.R., GOOD, R.A. & GEWURZ, H. (1973) Hereditary angio-neurotic oedema. 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