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This increase did not appear to be due to an increase in creatinine clearance and was found to be strongly correlated with an index designed to assess the severity and acuteness of the metabolic response of the body to hyperthyroidism. The potential clinical significance of this finding is discussed.<\/jats:p>","DOI":"10.1136\/pgmj.53.617.143","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"143-145","source":"Crossref","is-referenced-by-count":11,"title":["Zinc metabolism and thyroid status"],"prefix":"10.1093","volume":"53","author":[{"given":"W F","family":"Bremner","sequence":"first","affiliation":[{"name":"University Departments of Medical Cardiology and Pathological Biochemistry , Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G S","family":"Fell","sequence":"additional","affiliation":[{"name":"University Departments of Medical Cardiology and Pathological Biochemistry , Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1977,3,1]]},"reference":[{"key":"ref_1","first-page":"202","article-title":"An automated method for the direct determination of total serum cholesterol","volume":"26","author":"ANNAN, W.; ISHERWOOD, D.M.","year":"1969","unstructured":"ANNAN, W. & ISHERWOOD, D.M. (1969) An automated method for the direct determination of total serum cholesterol. Medical Laboratory Technology, 26, 202.","journal-title":"Medical Laboratory Technology"},{"key":"ref_2","first-page":"255","article-title":"Statsitical methods applied to the diagnosis of hypothyroidism","volume":"38","author":"BILLEWICZ, W.Z.; CHAPMAN, R.S.; CROOKS, J.; DAY, M.E.; GOSSAGE, J.; WAYNE, E.J.; YOUNG, J.J.","year":"1969","unstructured":"BILLEWICZ, W.Z., CHAPMAN, R.S., CROOKS, J., DAY, M.E., GOSSAGE, J., WAYNE, E.J. & YOUNG, J.J. (1969) Statsitical methods applied to the diagnosis of hypothyroidism. Quarterly Journal of Medicine, 38, 255.","journal-title":"Quarterly Journal of Medicine"},{"key":"ref_3","first-page":"211","article-title":"Statistical methods applied to the clinical diagnosis of thyrotoxicosis","volume":"38","author":"CROOKS, J.; MURRAY, I.P.C.; WAYNE, E.J.","year":"1959","unstructured":"CROOKS, J., MURRAY, I.P.C. & WAYNE, E.J. 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British Medical Journal, 4, 625.","journal-title":"British Medical Journal"},{"key":"ref_8","first-page":"249","article-title":"Determination of copper and zinc in plasma and urine by atomic absorption spectrophotometry","volume":"30","author":"PEASTON, R.F.","year":"1973","unstructured":"PEASTON, R.F. (1973) Determination of copper and zinc in plasma and urine by atomic absorption spectrophotometry. Medical Laboratory Technology, 30, 249.","journal-title":"Medical Laboratory Technology"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1530\/acta.0.0760645","article-title":"Red cell zinc and red cell zinc metalloenzymes in hyperthyroidism","volume":"76","author":"PENGARO, J.A.; WEINSTEIN, M.; DEVETAK, M.C.; SOTO, R.J.","year":"1974","unstructured":"PENGARO, J.A., WEINSTEIN, M., DEVETAK, M.C. & SOTO, R.J. (1974) Red cell zinc and red cell zinc metalloenzymes in hyperthyroidism. 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