{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T19:31:46Z","timestamp":1698003106372},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"622","license":[{"start":{"date-parts":[[1977,8,1]],"date-time":"1977-08-01T00:00:00Z","timestamp":239241600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1977,8,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Fourteen patients suffering from various degrees of bone dysplasia and mental handicap with superimposed neuroses or psychotic episodes are reported. Known biochemical and chromosomal causes are noted. Mental states associated with syndromes and mental malfunctioning or impairment because of skeletal defects or other factors are briefly discussed. High IgE was noted in the three cases of bone dysplasias suffering from chromosomal anomalies. Importance of early diagnosis, treatment and genetic counselling in bone dysplasias to prevent mental disorder is emphasized.<\/jats:p>","DOI":"10.1136\/pgmj.53.622.458","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"458-463","source":"Crossref","is-referenced-by-count":2,"title":["Bone dysplasias and mental functioning"],"prefix":"10.1093","volume":"53","author":[{"given":"J","family":"Jancar","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Stoke Park Hospital Group , Bristol"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1977,8,1]]},"reference":[{"key":"ref_1","first-page":"202","article-title":"Mental Deficiency-Stoke Park Studies. First series","author":"BATEs, R.M.","year":"1933","unstructured":"BATEs, R.M. (1933) Mental Deficiency-Stoke Park Studies. First series (Ed. by Richard J. A. Berry), p. 202. MacMillan and Co. Ltd, London."},{"key":"ref_2","series-title":"Proceedings of the London Conference. Scientific Study of Mental Deficiency","first-page":"329","article-title":"Mandibulo-facial dysostosis (BerryFranceschetti syndrome) associated with severe mental subnormality and consanguinity","volume":"1","author":"JANCAR, J.","year":"1962","unstructured":"JANCAR, J. (1962) Mandibulo-facial dysostosis (BerryFranceschetti syndrome) associated with severe mental subnormality and consanguinity. Proceedings of the London Conference. Scientific Study of Mental Deficiency, 1, 329."},{"key":"ref_3","series-title":"Proceedings of the International Copenhagen Congress for the Scientific Study of Mental Retardation","first-page":"179","article-title":"Mentally defective males with XXXXY chromosomes","volume":"1","author":"JANCAR, J.","year":"1964","unstructured":"JANCAR, J. (1964) Mentally defective males with XXXXY chromosomes. Proceedings of the International Copenhagen Congress for the Scientific Study of Mental Retardation, 1, 179."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/S0140-6736(68)91194-X","article-title":"XXYY with manic depression","volume":"ii,","author":"JANCAR, J.","year":"1968","unstructured":"JANCAR, J. (1968) XXYY with manic depression, Lancet, ii, 970.","journal-title":"Lancet"},{"key":"ref_5","first-page":"17","article-title":"Paroxysmal tachycardia, epilepsy, fragilitas ossium and mental retardation","volume":"84","author":"JANCAR, J.","year":"1969","unstructured":"JANCAR, J. (1969a) Paroxysmal tachycardia, epilepsy, fragilitas ossium and mental retardation. Bristol MedicoChirurgical Journal, 84, 17.","journal-title":"Bristol MedicoChirurgical Journal"},{"key":"ref_6","first-page":"8","article-title":"Potter's syndrome with mental retardation (Aurorenal syndrome: reno-facial dysplasia)","volume":"13","author":"JANCAR, J.","year":"(l969b)","unstructured":"JANCAR, J. (l969b) Potter's syndrome with mental retardation (Aurorenal syndrome: reno-facial dysplasia). Journal of Mental Deficiency Research, 13, 8.","journal-title":"Journal of Mental Deficiency Research"},{"key":"ref_7","first-page":"105","article-title":"Neuro-cutaneous disorders and mental functioning","volume":"126","author":"JANCAR, J.","year":"1975","unstructured":"JANCAR, J. (1975) Neuro-cutaneous disorders and mental functioning. British Journal of Psychiatry, 126, 105.","journal-title":"British Journal of Psychiatry"},{"key":"ref_8","first-page":"183","article-title":"Lesch-Nyhan syndrome (familial hyperuricaemia). Acta Universitatis Carolinae Medica","volume":"56","author":"JANCAR, J.; WILEY, Y.V.O.N.N.E.","year":"1973","unstructured":"JANCAR, J. & WILEY, YVONNE (1973) Lesch-Nyhan syndrome (familial hyperuricaemia). Acta Universitatis Carolinae Medica. Pragae, Monograph 56, 183.","journal-title":"Pragae, Monograph"},{"key":"ref_9","first-page":"316","article-title":"Two cases of Klippel-Feil syndrome associated with severe mental subnormality","volume":"28","author":"PETERS, J.J.","year":"1962","unstructured":"PETERS, J.J. (1962) Two cases of Klippel-Feil syndrome associated with severe mental subnormality, Radiography, 28, 316.","journal-title":"Radiography"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/53\/622\/458\/50202506\/postgradmedj-53-458.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/53\/622\/458\/50202506\/postgradmedj-53-458.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T14:25:43Z","timestamp":1683210343000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/53\/622\/458\/7038445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,8,1]]},"references-count":9,"journal-issue":{"issue":"622","published-online":{"date-parts":[[1977,8,1]]},"published-print":{"date-parts":[[1977,8,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.53.622.458","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1977,8]]},"published":{"date-parts":[[1977,8,1]]}}}