{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T17:47:01Z","timestamp":1780422421699,"version":"3.54.1"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"623","license":[{"start":{"date-parts":[[1977,9,1]],"date-time":"1977-09-01T00:00:00Z","timestamp":241920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1977,9,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>The natural history of Chagas' disease and its manifestations when the heart is involved are detailed clinically and pathologically. Three phases are recognized: the acute phase, lasting from 1-3 months, the latent phase, which may last from 10-20 years, and the chronic phase, which has the most serious manifestations. This phase is subdivided into three clinical stages. An analysis of the varied cardiac manifestations on 235 patients is included.<\/jats:p>","DOI":"10.1136\/pgmj.53.623.527","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"527-532","source":"Crossref","is-referenced-by-count":10,"title":["Diagnosis of Chagas' cardiomyopathy. Non-invasive techniques"],"prefix":"10.1093","volume":"53","author":[{"given":"J J","family":"Puigb\u00f3","sequence":"first","affiliation":[{"name":"Medical School, Central University of Venezuela, University Hospital of Caracas, and the Cardiovascular Diseases Department of the Ministry of Health and Social Welfare , Caracas, Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Valecillos","sequence":"additional","affiliation":[{"name":"Cardiovascular Diseases Department of the Ministry of Health and Social Welfare , Caracas, Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Hirschhaut","sequence":"additional","affiliation":[{"name":"Medical School, Central University of Venezuela, University Hospital of Caracas, and the Cardiovascular Diseases Department of the Ministry of Health and Social Welfare , Caracas, Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Giordano","sequence":"additional","affiliation":[{"name":"Cardiovascular Diseases Department of the Ministry of Health and Social Welfare , Caracas, Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Boccalandro","sequence":"additional","affiliation":[{"name":"Medical School, Central University of Venezuela, University Hospital of Caracas, and the Cardiovascular Diseases Department of the Ministry of Health and Social Welfare , Caracas, Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Su\u00e1rez","sequence":"additional","affiliation":[{"name":"Pathological Anatomy Institute, Central University of Venezuela , Caracas, Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J M","family":"Aparicio","sequence":"additional","affiliation":[{"name":"Cardiovascular Diseases Department of the Ministry of Health and Social Welfare , Caracas, Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1977,9,1]]},"reference":[{"key":"ref_1","article-title":"Hemibloqueos y zonas inactivables. Estudio electro y vectocardiografico. Resumenes 'VII Congreso Mundial de Cardiologia'. Enfermedad de Chagas y otras Miocardiopatias","author":"BOCCALANDRO, I.; HIRSCHHAUT, E.","year":"1974","unstructured":"BOCCALANDRO, I. & HIRSCHHAUT, E. (1974) Hemibloqueos y zonas inactivables. Estudio electro y vectocardiografico. Resumenes 'VII Congreso Mundial de Cardiologia'. Enfermedad de Chagas y otras Miocardiopatias. 38, 383. Buenos Aires."},{"key":"ref_2","first-page":"105","article-title":"La ecocardiografia aplicada al diagn6stico de las miocardiopatias. Signos ecocardiogrificos de la miocardiopatia chagisica","volume":"2","year":"1975","unstructured":"HERNANDEZ-PIERETTI, 0,. GORRiN ACOSTA, M., GALLARDOCOLINA, E. PIREZ-DiAZ, J.F., URBINA-QUINTANA, A., PLAJA, J., HERNANDEZ, M.I. DE & MORALES-BRICEiNo, E. (1975) La ecocardiografia aplicada al diagn6stico de las miocardiopatias. Signos ecocardiogrificos de la miocardiopatia chagisica. 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(1975) Estudio sobre la capacidad de trabajo y electrocardiograma de esfuerzo en lamiocardiopatia chagasica. Archivos Venezolanos de Cardiologia, 2, 13.","journal-title":"Archivos Venezolanos de Cardiologia"},{"key":"ref_6","article-title":"Ultrasound in the Diagnosis of Cardiovascular-Pulmonary Disease","author":"JOYNER, C.R.","year":"1974","unstructured":"JOYNER, C.R. (1974) Ultrasound in the Diagnosis of Cardiovascular-Pulmonary Disease. Year Book Medical Publishers, Inc., Chicago."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1161\/01.CIR.14.6.1035","article-title":"Chagas' disease. A clinical, epidemiologic and pathologic study","volume":"14","author":"LARANJA, F.S.; DIAS, E.; NOBREGA, G.; MIRANDA, A.","year":"1956","unstructured":"LARANJA, F.S., DIAS, E., NOBREGA, G. & MIRANDA, A. (1956) Chagas' disease. A clinical, epidemiologic and pathologic study. Circulation, 14, 1035.","journal-title":"Circulation"},{"key":"ref_8","article-title":"Algunos aspectos de anatomia patologica de cardite chagdsica cr6nica. Tese da Faculdade de Medicina da Universidade de Sao Paulo","author":"MIGONE, C.","year":"1958","unstructured":"MIGONE, C. (1958) Algunos aspectos de anatomia patologica de cardite chagdsica cr6nica. Tese da Faculdade de Medicina da Universidade de Sao Paulo."},{"key":"ref_9","first-page":"95","article-title":"Morfogenesis de las lesiones tempranas producidas por el Schizotrypanum cruzi en condiciones experimentales y sus correlaciones con la infecci6n humana. Archivos Venezolanos de Medicina Tropical y Parasitologia","volume":"5","author":"PIFANO, C.F.; ROMERO, J.; DOMiNGUEZ, A.","year":"1965","unstructured":"PIFANO, C.F., ROMERO, J. & DOMiNGUEZ, A. (1965) Morfogenesis de las lesiones tempranas producidas por el Schizotrypanum cruzi en condiciones experimentales y sus correlaciones con la infecci6n humana. Archivos Venezolanos de Medicina Tropical y Parasitologia Medica, 5, 95.","journal-title":"Medica"},{"key":"ref_10","article-title":"El vectorcardiograma en la miocardiopatia chagasica cr6nica. Cardiologia","author":"PILEGGI, F.; EBAID, M.; TRANCHESI, J.","year":"1961","unstructured":"PILEGGI, F., EBAID, M. & TRANCHESI, J. (1961) El vectorcardiograma en la miocardiopatia chagasica cr6nica. Cardiologia. Instituto Nacional de Cardiologia."},{"key":"ref_11","first-page":"91","article-title":"Chagas' heart disease. Clinical aspects","volume":"52","author":"PUIGB6, J.J.","year":"1968","unstructured":"PUIGB6, J.J. (1968) Chagas' heart disease. Clinical aspects. 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(1968) Clasificaci6n evolutiva de la miocardiopatia chagasica cr6nica. Acta medica venezolana, 15, 331.","journal-title":"Acta medica venezolana"},{"key":"ref_14","first-page":"339","article-title":"Estudio de la cardiopatia chagasica cr6nica. Empleo de la cineangiocardiografia","volume":"15","author":"PUIGB6, J.J.; PISANI, F.; BOCCALANDRO, I.; BLANCO, P.; MACHADO, I.; VALERO, J.A.","year":"1968","unstructured":"PUIGB6, J.J., PISANI, F., BOCCALANDRO, I., BLANCO, P., MACHADO, I. & VALERO, J.A. (1968) Estudio de la cardiopatia chagasica cr6nica. Empleo de la cineangiocardiografia. Acta medica venezolana, 15, 339.","journal-title":"Acta medica venezolana"},{"key":"ref_15","first-page":"203","article-title":"Los Hemibloqueos","author":"ROSENBAUM, M.B.; ELIZARI, M.V.; LAZZARI, J.O.","year":"1968","unstructured":"ROSENBAUM, M.B., ELIZARI, M.V. & LAZZARI, J.O. (1968) Los Hemibloqueos p. 203. 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(1974) Non-invasive Methods in Cardiology, p. 337."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/53\/623\/527\/50185763\/postgradmedj-53-527.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/53\/623\/527\/50185763\/postgradmedj-53-527.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T07:38:41Z","timestamp":1683531521000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/53\/623\/527\/7038492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,9,1]]},"references-count":18,"journal-issue":{"issue":"623","published-online":{"date-parts":[[1977,9,1]]},"published-print":{"date-parts":[[1977,9,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.53.623.527","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1977,9]]},"published":{"date-parts":[[1977,9,1]]}}}