{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,28]],"date-time":"2023-05-28T10:49:48Z","timestamp":1685270988420},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"627","license":[{"start":{"date-parts":[[1978,1,1]],"date-time":"1978-01-01T00:00:00Z","timestamp":252460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1978,1,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 72-year-old patient presented as a sealed perforated duodenal ulcer. This was later confirmed at operation when in addition a haemoperitoneum due to a lacerated friable spleen was discovered. The patient denied antecedent injury. The peripheral blood film was normal but a subsequent differential slide test for infectious mononucleosis was positive. Histology of the spleen showed hyperplasia of the red pulp in addition to capsular and trabecular infiltration with lymphocytes and atypical mononuclear cells confirming the diagnosis. Infectious mononucleosis in the elderly is rare and a complicating rupture of the spleen at this stage has not been reported previously. The diagnosis may depend on the histology alone because the peripheral blood film and serology can be negative. The possible role of the perforated duodenal ulcer is discussed.<\/jats:p>","DOI":"10.1136\/pgmj.54.627.51","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"51-55","source":"Crossref","is-referenced-by-count":2,"title":["Rupture of the spleen in a patient with a perforated duodenal ulcer and infectious mononucleosis"],"prefix":"10.1093","volume":"54","author":[{"given":"Robin","family":"Gray","sequence":"first","affiliation":[{"name":"Department of Surgery, Kings College Hospital , London SE5"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1978,1,1]]},"reference":[{"key":"ref_1","first-page":"403","article-title":"Death from idiopathic rupture of the spleen","volume":"2","author":"ATKINSON, E.","year":"1874","unstructured":"ATKINSON, E. (1874) Death from idiopathic rupture of the spleen. 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(1969) Occult rupture of the spleen. Surgery, Gynaecology and Obstetrics, 128, 1215.","journal-title":"Surgery, Gynaecology and Obstetrics; Occult rupture of the spleen"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1001\/jama.1961.73040370016014a","article-title":"Rupture of the spleen associated with pancreatitis","volume":"177","author":"GARDNER, R.J.; PRESTON, F.W.","year":"1961","unstructured":"GARDNER, R.J. & PRESTON, F.W. (1961) Rupture of the spleen associated with pancreatitis. Journal of the American Medical Association, 177, 784.","journal-title":"Journal of the American Medical Association"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1136\/bmj.1.5740.111-b","article-title":"Spontaneous rupture of the spleen","volume":"1","author":"GRECH, A.","year":"1971","unstructured":"GRECH, A. (1971) Spontaneous rupture of the spleen. 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(1973) Persistent haemagglutination for infectious mononucleosis in rheumatoid arthritis. British Medical Journal, 1, 591.","journal-title":"British Medical Journal"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1001\/archsurg.1972.04180050028007","article-title":"Spontaneous and pathological rupture of the spleen","volume":"104","author":"HYUN, B.H.; VARGA, C.F.; RUBIN, R.J.","year":"1972","unstructured":"HYUN, B.H., VARGA, C.F. & RUBIN, R.J. (1972) Spontaneous and pathological rupture of the spleen. Archives of Surgery. Chicago, 104, 652.","journal-title":"Archives of Surgery. Chicago"},{"key":"ref_14","first-page":"490","article-title":"A case of spontaneous rupture of the spleen","volume":"2","author":"MILLER, J.","year":"1961","unstructured":"MILLER, J. (1961) A case of spontaneous rupture of the spleen. 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Part"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/S0022-5347(17)62903-3","article-title":"Rupture of the spleen secondary to renal sepsis","volume":"98","author":"REISMAN, D.D.; LOGAN, D.J.","year":"1968","unstructured":"REISMAN, D.D. & LOGAN, D.J. (1968) Rupture of the spleen secondary to renal sepsis. Journal of Urology, 98, 426.","journal-title":"Journal of Urology"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1001\/jama.1971.03190210151022","article-title":"False positive infectious mononucleosis spot test in pancreatic carcinoma","volume":"218","author":"SADOFF, L. & GOLDSMITH, 0","year":"1971","unstructured":"SADOFF, L. & GOLDSMITH, 0. (1971) False positive infectious mononucleosis spot test in pancreatic carcinoma. 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Chicago, 111, 610.","journal-title":"Archives of Surgery. Chicago"},{"key":"ref_25","first-page":"995","article-title":"The danger of the ruptured spleen in infectious mononucleosis","volume":"61","author":"YURKO, A.A.; WINEGARNER, F.G.; KINSEY, D.L.","year":"1965","unstructured":"YURKO, A.A., WINEGARNER, F.G. & KINSEY, D.L. (1965) The danger of the ruptured spleen in infectious mononucleosis. Ohio State Medical Journal, 61, 995.","journal-title":"Ohio State Medical Journal"},{"key":"ref_26","first-page":"55","article-title":"Postgraduate Medical Journal","volume":"54","year":"1978","unstructured":"Postgraduate Medical Journal (January 1978) 54, 55-57."},{"key":"ref_27","article-title":"Southampton Summary The association of chronic active hepatitis with haemolytic anaemia is well known. Both conditions may respond to steroid therapy which, in common with other causes of suppressed T-lymphocyte function, predispose to many types of infection. A case is described in which transient Listeria monocytogenes bacteraemia occurred and the patient recovered without antimicrobial therapy","author":"Hospital, Southampton General","unstructured":"Southampton General Hospital, Southampton Summary The association of chronic active hepatitis with haemolytic anaemia is well known. Both conditions may respond to steroid therapy which, in common with other causes of suppressed T-lymphocyte function, predispose to many types of infection. A case is described in which transient Listeria monocytogenes bacteraemia occurred and the patient recovered without antimicrobial therapy."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/54\/627\/51\/50158400\/postgradmedj-54-51.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/54\/627\/51\/50158400\/postgradmedj-54-51.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T08:05:50Z","timestamp":1683533150000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/54\/627\/51\/7063195"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,1,1]]},"references-count":27,"journal-issue":{"issue":"627","published-online":{"date-parts":[[1978,1,1]]},"published-print":{"date-parts":[[1978,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.54.627.51","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1978,1]]},"published":{"date-parts":[[1978,1,1]]}}}