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In bone, the concentration was (mean \u00b1 s.e. mean) 5\u00b701 microgram\/ml \u00b1 1\u00b716, N=10; in capsule, 3\u00b729 microgram\/ml \u00b1 0\u00b771, N=12; measured between 1\u00b775 and 3\u00b775 hr after intramuscular and intravenous injections, and in drainage fluid it amounted to 4\u00b761 microgram\/ml \u00b1 0\u00b738, N=11 in 48 hr. Two patients developed diarrhoea which settled within a short period.<\/jats:p>","DOI":"10.1136\/pgmj.54.628.65","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"65-67","source":"Crossref","is-referenced-by-count":22,"title":["Penetration into bone and tissues of clindamycin phosphate"],"prefix":"10.1093","volume":"54","author":[{"given":"P","family":"Baird","sequence":"first","affiliation":[{"name":"Royal National Orthopaedic Hospital and Edgware General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Hughes","sequence":"additional","affiliation":[{"name":"Royal National Orthopaedic Hospital and Edgware General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Royal National Orthopaedic Hospital and Edgware General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Willmot","sequence":"additional","affiliation":[{"name":"Royal National Orthopaedic Hospital and Edgware General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1978,2,1]]},"reference":[{"issue":"371","key":"ref_1","article-title":"Lincomycin bone concentrations during total hip replacement","volume":"2","author":"BEAVIS, J.P.; HOSSACK, G.M.; PARSONS, R.L.; PADDOCK, G.M.","year":"1975","unstructured":"BEAVIS, J.P., HOSSACK, G.M., PARSONS, R.L. & PADDOCK, G.M. 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