{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T14:03:46Z","timestamp":1699106626534},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"635","license":[{"start":{"date-parts":[[1978,9,1]],"date-time":"1978-09-01T00:00:00Z","timestamp":273456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1978,9,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Subacute sclerosing panencephalitis (SSPE) is now considered to be caused by measles virus. There are four diagnostic criteria, namely the clinical picture, a characteristic EEG, serology of serum and CSF and brain histology. A register of cases in the U.K. has been kept since 1971, and up to September 1977, ninety-six patients have been reported. The male\/female ratio is 2:1. The disease most commonly affects children between the ages of nine and eleven years who usually have had measles at a very early age. The average delay between the measles infection and onset of SSPE was 6.8 years and of the thirty-four patients known to have died the average survival times was 1.2 years. There are still many questions about the pathogenesis and epidemiology of SSPE that have yet to be answered.<\/jats:p>","DOI":"10.1136\/pgmj.54.635.587","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"587-590","source":"Crossref","is-referenced-by-count":8,"title":["Subacute sclerosing panencephalitis"],"prefix":"10.1093","volume":"54","author":[{"given":"M H","family":"Bellman","sequence":"first","affiliation":[{"name":"Department of Community Medicine, Middlesex Hospital Medical School , London W1P 7PN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Dick","sequence":"additional","affiliation":[{"name":"Institute of Child Health, University of London , London WC1N 1EH"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1978,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/brain\/88.5.953","article-title":"Viral antibody in the cerebrospinal fluid and serum of multiple sclerosis patients","volume":"88","author":"CLARKE, J.K.; DANE, D.S.; DICK, G.W.A.","year":"1965","unstructured":"CLARKE, J.K., DANE, D.S. & DICK, G.W.A. (1965) Viral antibody in the cerebrospinal fluid and serum of multiple sclerosis patients. Brain, 88, 953.","journal-title":"Brain"},{"key":"ref_2","article-title":"Measles-virus antibody and antigen in subacute sclerosing panencephalitis","volume":"542","author":"CONNOLLY, J.H.; ALLEN, I.V.; HURWIT7, L.J.; MILLAR, J.H.D.","year":"1967","unstructured":"CONNOLLY, J.H., ALLEN, I.V., HURWIT7, L.J. & MILLAR, J.H.D. (1967) Measles-virus antibody and antigen in subacute sclerosing panencephalitis. Lancet, i, 542.","journal-title":"Lancet"},{"key":"ref_3","first-page":"7","article-title":"Cellular inclusions in cerebral lesion of lethargic encephalitis","volume":"9","author":"DAWSON, JR, J.R.","year":"1933","unstructured":"DAWSON JR, J.R. (1933) Cellular inclusions in cerebral lesion of lethargic encephalitis. American Journal of Pathology, 9, 7.","journal-title":"American Journal of Pathology"},{"key":"ref_4","first-page":"11","article-title":"Further epidemiological studies of subacute sclerosing panencephalitis","volume":"ii,","author":"DETELS, R.; BRODY, J.A.; MCNEW, J.; EDGAR, A.H.","year":"1973","unstructured":"DETELS, R., BRODY, J.A., MCNEW, J. & EDGAR, A.H. (1973) Further epidemiological studies of subacute sclerosing panencephalitis. Lancet, ii, 11.","journal-title":"Lancet"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1038\/221974a0","article-title":"Subacute sclerosing panencephalitis","volume":"221","author":"HORTA-BARBOSA, L.; FucCILLO, D.A.; SEVER, J.L.; ZEMAN, W.","year":"1969","unstructured":"HORTA-BARBOSA, L., FucCILLO, D.A., SEVER, J.L. & ZEMAN, W. (1969) Subacute sclerosing panencephalitis. Nature. London, 221, 974.","journal-title":"Nature. London"},{"key":"ref_6","first-page":"7","article-title":"Subacute sclerosing panencephalitis in the Cape Province","volume":"48","author":"MCDONALD, R.; Kipps, A.; LEARY, P.M.","year":"1974","unstructured":"MCDONALD, R., Kipps, A. & LEARY, P.M. (1974) Subacute sclerosing panencephalitis in the Cape Province. South African Medical Journal, 48, 7.","journal-title":"South African Medical Journal"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1542\/peds.59.4.505","article-title":"Epidemiologic studies of measles, measles vaccine, and subacute sclerosing panencephalitis","volume":"59","author":"MODLIN, J.F.; JABBOUR, J.T.; WITTE, J.J.; HALSEY, N.A.","year":"1977","unstructured":"MODLIN, J.F., JABBOUR, J.T., WITTE, J.J. & HALSEY, N.A. (1977) Epidemiologic studies of measles, measles vaccine, and subacute sclerosing panencephalitis. Pediatrics, 59, 505.","journal-title":"Pediatrics"},{"key":"ref_8","first-page":"113","article-title":"Studies of blood cerebrospinal fluid barrier to antibodies and other proteins. Neurology","volume":"13","author":"SHERWIN, A.L.; RICHTER, M.; COSGROVE, J.B.R.; ROSE, B.","year":"1963","unstructured":"SHERWIN, A.L., RICHTER, M., COSGROVE, J.B.R. & ROSE, B. (1963) Studies of blood cerebrospinal fluid barrier to antibodies and other proteins. Neurology. Minneapolis, 13, 113.","journal-title":"Minneapolis"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/oxfordjournals.aje.a112206","article-title":"Subacute sclerosing panencephalitis: an epidemiologic study in Israel","volume":"103","author":"SOFFER, D.; RANNON, L.; ALTER, M.; KAHANA, E.; FELDMAN, S.","year":"1976","unstructured":"SOFFER, D., RANNON, L., ALTER, M., KAHANA, E. & FELDMAN, S. (1976) Subacute sclerosing panencephalitis: an epidemiologic study in Israel. American Journal of Epidemiology, 103, 67.","journal-title":"American Journal of Epidemiology"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1126\/science.154.3751.899","article-title":"Subacute sclerosing leuco-encephalitis: ultra-structure of intranuclear and intracytoplasmic inclusions","volume":"154","author":"TELLEZ-NAGEL, I.; HARTER, D.H.","year":"1966","unstructured":"TELLEZ-NAGEL, I. & HARTER, D.H. (1966) Subacute sclerosing leuco-encephalitis: ultra-structure of intranuclear and intracytoplasmic inclusions. Science. Washington, 154, 899.","journal-title":"Science. Washington"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/54\/635\/587\/50158845\/postgradmedj-54-587.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/54\/635\/587\/50158845\/postgradmedj-54-587.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T06:30:40Z","timestamp":1684823440000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/54\/635\/587\/7063587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,9,1]]},"references-count":10,"journal-issue":{"issue":"635","published-online":{"date-parts":[[1978,9,1]]},"published-print":{"date-parts":[[1978,9,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.54.635.587","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1978,9]]},"published":{"date-parts":[[1978,9,1]]}}}