{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T06:10:05Z","timestamp":1683612605008},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"649","license":[{"start":{"date-parts":[[1979,11,1]],"date-time":"1979-11-01T00:00:00Z","timestamp":310262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1979,11,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>The clinical features of 3 Ethiopian patients presenting with the complete syndrome of testicular feminization are described. All 3 were seen because of primary amenorrhoea. At laparotomy, one patient had testes located intra-abdominally, a second lodged in the inguinal canals and a third as masses in the labia majora. Also, one of these patients had bilateral inguinal herniae, a usual feature of this syndrome. Since the incidence of malignancy is high among individuals with undescended testes, they were removed in 2 patients. In the third patient, however, the testes were not removed because of delay in development of secondary sex characteristics. The literature on testicular feminization is also briefly reviewed.<\/jats:p>","DOI":"10.1136\/pgmj.55.649.844","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"844-848","source":"Crossref","is-referenced-by-count":0,"title":["Testicular feminization syndrome: a report of three Ethiopian patients and a brief review"],"prefix":"10.1093","volume":"55","author":[{"given":"E","family":"Tsega","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Black Lion Hospital, Faculty of Medicine, Addis Ababa University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Damtew","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Black Lion Hospital, Faculty of Medicine, Addis Ababa University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1979,11,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1056\/NEJM197606102942405","article-title":"Mechanism of action of the sex steroid hormones","volume":"294","author":"CHAN, L.; MALLEY, B.W.","year":"1976","unstructured":"CHAN, L. & MALLEY, B.W. (1976) Mechanism of action of the sex steroid hormones. New England Journal ofMedicine, 294, 1322.","journal-title":"New England Journal ofMedicine"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1210\/jcem-26-5-493","article-title":"Further evidence of a target organ defect in the syndrome of testicular feminization","volume":"26","author":"FRENCH, F.S.; VANWYK, J.J.; BEGGETT, B.; EASTERLING, W.E.; TALBERT, L.M.; JOHNSTON, F.R.; FORCHIELLI, E.; DEY, A.C.","year":"1966","unstructured":"FRENCH, F.S., VANWYK, J.J., BEGGETT, B., EASTERLING, W.E., TALBERT, L.M., JOHNSTON, F.R., FORCHIELLI, E. & DEY, A.C. (1966) Further evidence of a target organ defect in the syndrome of testicular feminization. Journal of Clinical Endocrinology, 26, 493.","journal-title":"Journal of Clinical Endocrinology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/S0002-9378(16)36206-8","article-title":"Gynecological operations in 94 patients with intersexuality. Implications concerning the endocrine theory of sexual differentiation","volume":"82","author":"JONES, H.W.; WILKINS, L.","year":"1961","unstructured":"JONES, H.W. & WILKINS, L. (1961) Gynecological operations in 94 patients with intersexuality. Implications concerning the endocrine theory of sexual differentiation. American Journal of Obstetrics and Gynecology, 82, 1142.","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"ref_4","first-page":"15","article-title":"In: Hermaphroditism, Genital Anomalies and Related Disorders","volume":"124","author":"JOST, A.","year":"1958","unstructured":"JOST, A. (1958) In: Hermaphroditism, Genital Anomalies and Related Disorders, p. 15, by H.W. Jones Jr and W. Wilkins, Williarns & Wilkins Co., Baltimore. MANUEL, M., KATAYAMA, K.P. & JONES Jr, H.W. (1976) The age of occurrence of gonadal tumor in intersex patients with a Y chromosome. American Journal of Obstetrics and Gynecology, 124, 293.","journal-title":"American Journal of Obstetrics and Gynecology; The age of occurrence of gonadal tumor in intersex patients with a Y chromosome"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/0002-9378(53)90359-7","article-title":"The syndrome of testicular feminization in male pseudohermaphrodites","volume":"65","author":"MORRIS, J.M.","year":"1953","unstructured":"MORRIS, J.M. (1953) The syndrome of testicular feminization in male pseudohermaphrodites. American Journal of Obstetrics and Gynecology, 65, 1192.","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"ref_6","first-page":"731","article-title":"Further observations on the syndrome, 'testicular feminization'","volume":"87","author":"MORRIS, J.M.; MAHESH, V.B.","year":"1963","unstructured":"MORRIS, J.M. & MAHESH, V.B. (1963) Further observations on the syndrome, 'testicular feminization'. American Journal of Obstetrics and Gynecology, 87, 731.","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1056\/NEJM197702242960808","article-title":"Pelvic mass in a 53-year-old woman with primary amenorrhea","volume":"296","author":"RICHARDSON, G.S.; ROBBOX, S.J.","year":"1977","unstructured":"RICHARDSON, G.S. & ROBBOX, S.J. (1977) Pelvic mass in a 53-year-old woman with primary amenorrhea. New England Journal of Medicine, 296, 439.","journal-title":"New England Journal of Medicine"},{"key":"ref_8","first-page":"813","article-title":"Testicular feminization with and without clitoral enlargement","volume":"94","author":"TETER, J.; BOCZKOWSKI, K.","year":"1966","unstructured":"TETER, J. & BOCZKOWSKI, K. (1966) Testicular feminization with and without clitoral enlargement. American Joutrnal of Obstetrics and Gynecology, 94, 813.","journal-title":"American Joutrnal of Obstetrics and Gynecology"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/55\/649\/844\/50093663\/postgradmedj-55-844.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/55\/649\/844\/50093663\/postgradmedj-55-844.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T10:05:55Z","timestamp":1683540355000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/55\/649\/844\/7063860"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,11,1]]},"references-count":8,"journal-issue":{"issue":"649","published-online":{"date-parts":[[1979,11,1]]},"published-print":{"date-parts":[[1979,11,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.55.649.844","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1979,11]]},"published":{"date-parts":[[1979,11,1]]}}}