{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:23:46Z","timestamp":1760189026322},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"652","license":[{"start":{"date-parts":[[1980,2,1]],"date-time":"1980-02-01T00:00:00Z","timestamp":318211200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1980,2,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 62-year-old Indian with diabetic nephropathy controlled with metformin, developed miliary tuberculosis for which he was treated with rifampicin, isoniazid and ethambutol. Soon afterwards he developed cholestatic hepatitis and visual disturbance. Rifampicin and ethambutol were stopped. Streptomycin caused vertigo and had to be stopped. The introduction of para-aminosalicylic acid (PAS) led to hypoglycaemic coma. Metformin was stopped. Hypoglycaemic coma recurred. PAS was stopped and the patient\u2019s blood glucose concentrations became normal. Treatment with isoniazid and ethambutol led to total recovery from pulmonary tuberculosis. The induction of hypoglycaemia with PAS in this patient suggests a potential role for PAS in the treatment of diabetes mellitus.<\/jats:p>","DOI":"10.1136\/pgmj.56.652.135","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"135-136","source":"Crossref","is-referenced-by-count":6,"title":["<i>Para<\/i>-aminosalicylic acid-induced hypoglycaemia in a patient with diabetic nephropathy"],"prefix":"10.1093","volume":"56","author":[{"given":"P","family":"Dandona","sequence":"first","affiliation":[{"name":"Royal Free Hospital , Pond Street, London NW3 2QG"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Greenbury","sequence":"additional","affiliation":[{"name":"Royal Free Hospital , Pond Street, London NW3 2QG"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A G","family":"Beckett","sequence":"additional","affiliation":[{"name":"Royal Free Hospital , Pond Street, London NW3 2QG"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1980,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1002\/jps.2600571218","article-title":"Hyperglycemic activity and chemical structure of salicylates","volume":"57","author":"FANG, V.; FOYE, W.O.; ROBINSON, S.M.; JENKINS, H.J.","year":"1968","unstructured":"FANG, V., FOYE, W.O., ROBINSON, S.M. & JENKINS, H.J. (1968) Hyperglycemic activity and chemical structure of salicylates. Journal of Pharmaceutical Sciences, 57, 2111.","journal-title":"Journal of Pharmaceutical Sciences"},{"key":"ref_2","first-page":"419","article-title":"The response of blood glucose to intravenous salicylate","volume":"10","author":"GILGORE, S.G.; Rupp, J.J.","year":"1961","unstructured":"GILGORE, S.G. & Rupp, J.J. (1961) The response of blood glucose to intravenous salicylate. Metabolism, 10, 419.","journal-title":"Metabolism"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1136\/bmj.1.5126.897","article-title":"The insulin equivalence of salicylate","volume":"1","author":"REID, J.; LIGHTBODY, T.D.","year":"1959","unstructured":"REID, J. & LIGHTBODY, T.D. (1959) The insulin equivalence of salicylate. British Medical Journal, 1, 897.","journal-title":"British Medical Journal"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1136\/bmj.2.5053.1071","article-title":"Aspirin and diabetes mellitus","volume":"2","author":"REID, J.; MACDOUGALL, A.J.; ANDREWS, M.M.","year":"1957","unstructured":"REID, J., MACDOUGALL, A.J. & ANDREWS, M.M. (1957) Aspirin and diabetes mellitus. British Medical Journal, 2, 1071.","journal-title":"British Medical Journal"},{"key":"ref_5","first-page":"31","article-title":"Pulmonary tuberculosis and diabetes mellitus","volume":"26","author":"TURNER-WARWICK, M.","year":"1957","unstructured":"TURNER-WARWICK, M. (1957) Pulmonary tuberculosis and diabetes mellitus. Quarterly Journal of Medicine, 26, 31.","journal-title":"Quarterly Journal of Medicine"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/56\/652\/135\/49291345\/postgradmedj-56-135.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/56\/652\/135\/49291345\/postgradmedj-56-135.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T13:20:53Z","timestamp":1681996853000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/56\/652\/135\/7050508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,2,1]]},"references-count":5,"journal-issue":{"issue":"652","published-online":{"date-parts":[[1980,2,1]]},"published-print":{"date-parts":[[1980,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.56.652.135","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1980,2]]},"published":{"date-parts":[[1980,2,1]]}}}