{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:49:40Z","timestamp":1790984980505,"version":"4.1.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"652","license":[{"start":{"date-parts":[[1980,2,1]],"date-time":"1980-02-01T00:00:00Z","timestamp":318211200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1980,2,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Plasma 25-OHD levels were measured in the same 26 Caucasian women before pregnancy and during the first, second and third trimesters of their pregnancy. This was done to assess whether pregnancy alters vitamin D status in healthy women. During most times of the year there was no association between the 25-OHD levels and the stage of pregnancy, but between January and March there was a progressive fall in 25-OHD levels with each trimester. When 25-OHD levels were related to hours of possible sunlight exposure a negative association between 25-OHD levels and stage of pregnancy was noted only in subjects with the lowest possible exposure to sunlight. These observations suggest that pregnancy has an effect on vitamin D metabolism, but that in healthy Caucasian women these effects only become manifest where there is a low level of exposure to sunlight.<\/jats:p>","DOI":"10.1136\/pgmj.56.652.75","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"75-79","source":"Crossref","is-referenced-by-count":29,"title":["The effects of season and stage of pregnancy on plasma 25-hydroxy-vitamin D concentrations in pregnant women"],"prefix":"10.1093","volume":"56","author":[{"given":"W J","family":"MacLennan","sequence":"first","affiliation":[{"name":"Department of Geriatric Medicine, Faculty of Medicine, University of Southampton"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Faculty of Medicine, University of Southampton"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J M","family":"Darmady","sequence":"additional","affiliation":[{"name":"Basingstoke General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1980,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1210\/jcem-38-6-1046","article-title":"A rapid assay for 25-OH vitamin D without preparative chromatography","volume":"38","author":"BELSEY, R.E.; LUCA, D.E.; F., H.; POTTS, T.J.","year":"1974","unstructured":"BELSEY, R.E., DE LUCA, H.F. & POTTS, T.J. (1974) A rapid assay for 25-OH vitamin D without preparative chromatography. Journal of Clinical Endocrinology and Metabolism, 38, 1046.","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1210\/jcem-34-5-767","article-title":"Physiologic hyperparathyroidism in pregnancy","volume":"34","author":"CUSHARD, W.G.; CREDITOR, M.; CANTERBURY, J.M.; REIss, E.","year":"1972","unstructured":"CUSHARD, W.G., CREDITOR, M., CANTERBURY, J.M. & REIss, E. (1972) Physiologic hyperparathyroidism in pregnancy. Journal of Clinical Endocrinology and Metabolism, 34, 767.","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/S0140-6736(75)90430-4","article-title":"Plasma 25-hydroxyvitamin D levels during pregnancy in Caucasians and in vegetarian and non vegetarian Asians","volume":"ii,","author":"DENT, C.E.; GUPTA, M.M.","year":"1975","unstructured":"DENT, C.E. & GUPTA, M.M. (1975) Plasma 25-hydroxyvitamin D levels during pregnancy in Caucasians and in vegetarian and non vegetarian Asians. Lancet, ii, 1057.","journal-title":"Lancet"},{"key":"ref_4","first-page":"1521","article-title":"Osteomalacia in Asians","volume":"1","author":"FELTON, D.J.C.; STONE, W.D.","year":"1966","unstructured":"FELTON, D.J.C. & STONE, W.D. (1966) Osteomalacia in Asians. British Medical Journal, 1, 1521.","journal-title":"British Medical Journal"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/S0022-3476(74)80024-7","article-title":"Human perinatal vitamin D metabolism I. 25-hydroxyvitamin D in maternal and cord blood","volume":"84","author":"HILLMAN, L.S.; HADDAD, J.G.","year":"1974","unstructured":"HILLMAN, L.S. & HADDAD, J.G. (1974) Human perinatal vitamin D metabolism I. 25-hydroxyvitamin D in maternal and cord blood. Journal of Pediatrics, 84, 742.","journal-title":"Journal of Pediatrics"},{"key":"ref_6","article-title":"Seasonal variations in serum 25-hydroxy-cholecalciferol in healthy people","volume":"536","author":"MCLAUGHLIN, M.; FAIRNEY, A.; LESTER, E.; RAGGATT, P.R.; BROWN, D.J.; WILLS, M.R.","year":"1974","unstructured":"MCLAUGHLIN, M., FAIRNEY, A., LESTER, E., RAGGATT, P.R., BROWN, D.J. & WILLS, M.R. (1974) Seasonal variations in serum 25-hydroxy-cholecalciferol in healthy people. Lancet, i, 536.","journal-title":"Lancet"},{"key":"ref_7","article-title":"Enamel hypoplasia of the teeth associated with neonatal tetany: a manifestation of maternal vitamin D","author":"PURVIs, R.J.; MACKAY, G.S.; COCKBURN, F.; BARRIE, W.J.M.; WILKINSON, E.M.; BELTON, N.R.; FORFAR, J.O.","year":"1973","unstructured":"PURVIs, R.J., MACKAY, G.S., COCKBURN, F., BARRIE, W.J.M., WILKINSON, E.M., BELTON, N.R. & FORFAR, J.O. (1973) Enamel hypoplasia of the teeth associated with neonatal tetany: a manifestation of maternal vitamin D"},{"key":"ref_8","article-title":"Antenatal factors associated with neonatal hypocalcaemic convulsions","volume":"809","author":"ROBERTS, S.A.; COHEN, M.D.; FORFAR, J.O.","year":"1973","unstructured":"ROBERTS, S.A., COHEN, M.D. & FORFAR, J.O. (1973) Antenatal factors associated with neonatal hypocalcaemic convulsions. Lancet, ii, 809.","journal-title":"Lancet"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/247563a0","article-title":"Seasonal changes in human plasma levels of 25-hydroxyvitamin D","volume":"247","author":"STAMP, T.C.B.; ROUND, J.M.","year":"1974","unstructured":"STAMP, T.C.B. & ROUND, J.M. (1974) Seasonal changes in human plasma levels of 25-hydroxyvitamin D. Nature. London, 247, 563.","journal-title":"Nature. London"},{"key":"ref_10","article-title":"Altered vitamin D metabolism in pregnancy","author":"TURTON, C.W.G.; STAMP, T.C.B.; STANLEY, P.; MAXWELL, J.D.","year":"1977","unstructured":"TURTON, C.W.G., STAMP, T.C.B., STANLEY, P. & MAXWELL, J.D. (1977) Altered vitamin D metabolism in pregnancy."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/56\/652\/75\/49291401\/postgradmedj-56-75.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/56\/652\/75\/49291401\/postgradmedj-56-75.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T13:20:56Z","timestamp":1681996856000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/56\/652\/75\/7050534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,2,1]]},"references-count":10,"journal-issue":{"issue":"652","published-online":{"date-parts":[[1980,2,1]]},"published-print":{"date-parts":[[1980,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.56.652.75","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1980,2]]},"published":{"date-parts":[[1980,2,1]]}}}