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The colour change became apparent only after the correction of a severe postoperative hyponatraemic alkalosis, the urinary pH had become alkaline, as melanin formation in acid urine is very slow.<\/jats:p>","DOI":"10.1136\/pgmj.56.662.877","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:39:26Z","timestamp":1230583166000},"page":"877-878","source":"Crossref","is-referenced-by-count":8,"title":["Black urine"],"prefix":"10.1093","volume":"56","author":[{"given":"P","family":"Altmann","sequence":"first","affiliation":[{"name":"Northwick Park Hospital , Watford Road, Harrow, Middlesex HA1 3UJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M A","family":"Mansell","sequence":"additional","affiliation":[{"name":"Northwick Park Hospital , Watford Road, Harrow, Middlesex HA1 3UJ"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1980,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/ki.1976.82","article-title":"Effects on the central nervous system of hypernatremic and hyponatremic states","volume":"10","author":"ARIEFF, A.I.; GUISADO, R.","year":"1976","unstructured":"ARIEFF, A.I. & GUISADO, R. (1976) Effects on the central nervous system of hypernatremic and hyponatremic states. Kidney International, 10, 104.","journal-title":"Kidney International"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0022-3565(25)26714-3","article-title":"The metabolism of methyldopa in hypertensive human subjects","volume":"143","author":"BUHS, R.P.; BECK, J.L.; SPETH, O.C.; SMITH, J.L.; TRENNER, N.R.; CANNON, P.J.; LARAGH, J.H.","year":"1964","unstructured":"BUHS, R.P., BECK, J.L., SPETH, O.C., SMITH, J.L., TRENNER, N.R., CANNON, P.J. & LARAGH, J.H. (1964) The metabolism of methyldopa in hypertensive human subjects. Journal of Pharmacology and Experimental Therapeutics, 143, 205.","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"ref_3","article-title":"Red urine associated with methyldopa treatment","volume":"326","author":"CARDWELL, J.B.","year":"1969","unstructured":"CARDWELL, J.B. (1969) Red urine associated with methyldopa treatment. Lancet, ii, 326.","journal-title":"Lancet"},{"key":"ref_4","first-page":"40","article-title":"Clinical Diagnosis by Laboratory Methodsn","volume":"291","author":"DAVIDSOHN, I.; HENRY, J.B.","year":"1969","unstructured":"DAVIDSOHN, I. & HENRY, J.B. (Ed.) (1969) Clinical Diagnosis by Laboratory Methods, 14th Edn, p. 40. W. B. Saunders and Co., Philadelphia. DEVERAUX, M.W. & MANCALL, E.L. (1974) Brown urine, bleach and L-dopa. New England Journal of Medicine, 291, 1142.","edition":"14","journal-title":"New England Journal of Medicine; Brown urine, bleach and L-dopa"},{"key":"ref_5","first-page":"286","article-title":"Clinical Laboratory Methods and Diagnosis","volume":"196","author":"FRANKEL, S.; REITMAN, S.; SONNENWIRTH, A.C.","year":"1970","unstructured":"FRANKEL, S., REITMAN, S. & SONNENWIRTH, A.C. (Eds) (1970) Clinical Laboratory Methods and Diagnosis, 7th Edn, p. 1046. C. V. Mosby Co., St Louis, Missouri. LIPSMEYER, E. & ACHERMAN, G.L. (1966) Irreversible brain damage after water intoxication. Journal of the American Medical Association, 196, 286.","edition":"7th Edn","journal-title":"Journal of the American Medical Association; Irreversible brain damage after water intoxication"},{"key":"ref_6","first-page":"101","article-title":"Renal and Electrolyte Disorders","author":"SCHRIER, R.W.","year":"1976","unstructured":"SCHRIER, R.W. 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