{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T18:10:56Z","timestamp":1683742256674},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"665","license":[{"start":{"date-parts":[[1981,3,1]],"date-time":"1981-03-01T00:00:00Z","timestamp":352252800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,3,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Blood vitamin status (B1, B2 and B6) was assessed by erythrocytic enzyme activation tests in 7 male and 1 female chronic alcoholics (mean age (\u00b1s.d.), 43\u00b712 (13\u00b77) years; range, 25-64 years) on admission and 6 hr later on the same day after oral administration of a single dose of polyvitamin. Seven out of 8 patients were found to be deficient in vitamin B1, 5 in B6 and none in B2. But after single-dose oral therapy, tendency to improvement of blood vitamin status was clearly evident in all patients. It is therefore suggested that a subgroup of chronic alcoholics may benefit from oral supplementation of vitamins. Clinical implications of vitamin deficiency in chronic alcoholics are briefly discussed.<\/jats:p>","DOI":"10.1136\/pgmj.57.665.164","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:43:59Z","timestamp":1230583439000},"page":"164-166","source":"Crossref","is-referenced-by-count":0,"title":["Blood vitamin status in chronic alcoholics after a single dose of polyvitamin. A preliminary report"],"prefix":"10.1093","volume":"57","author":[{"given":"Sisir K","family":"Majumdar","sequence":"first","affiliation":[{"name":"Elmdene Alcoholic Treatment Unit, Bexley Hospital , Kent"},{"name":"Gastroenterology & Liver Unit, Greenwich District Hospital , London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G K","family":"Shaw","sequence":"additional","affiliation":[{"name":"Elmdene Alcoholic Treatment Unit, Bexley Hospital , Kent"},{"name":"Gastroenterology & Liver Unit, Greenwich District Hospital , London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan D","family":"Thomson","sequence":"additional","affiliation":[{"name":"Elmdene Alcoholic Treatment Unit, Bexley Hospital , Kent"},{"name":"Gastroenterology & Liver Unit, Greenwich District Hospital , London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1981,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1093\/ajcn\/27.11.1221","article-title":"Vitamin B1 status in pregnancy","volume":"27","author":"HELLER, S.; SALKELD, R.M.; KORNER, W.F.","year":"1974","unstructured":"HELLER, S., SALKELD, R.M. & KORNER, W.F. (1974a) Vitamin B1 status in pregnancy. American Journal of Clinical Nutrition, 27, 1221.","journal-title":"American Journal of Clinical Nutrition"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1093\/ajcn\/27.11.1225","article-title":"Riboflavin status in pregnancy","volume":"27","author":"HELLER, S.; SALKELD, R.M.; KORNER, W.F.","year":"1974","unstructured":"HELLER, S., SALKELD, R.M. & KORNER, W.F. (1974b) Riboflavin status in pregnancy. American Journal of Clinical Nutrition, 27, 1225.","journal-title":"American Journal of Clinical Nutrition"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0025-7125(16)32660-8","article-title":"Nutritional deficiencies in liver disease","volume":"54","author":"LEEVY, C.M.; BAKER, H.","year":"1970","unstructured":"LEEVY, C.M. & BAKER, H. (1970) Nutritional deficiencies in liver disease. Medical Clinics of North America, 54, 467.","journal-title":"Medical Clinics of North America"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/ajcn\/23.4.493","article-title":"Vitamins and liver injury","volume":"23","author":"LEEVY, C.M.; THOMSON, A.D.; BAKER, H.","year":"1970","unstructured":"LEEVY, C.M., THOMSON, A.D. & BAKER, H. (1970) Vitamins and liver injury. American Journal of Clinical Nutrition, 23, 493.","journal-title":"American Journal of Clinical Nutrition"},{"key":"ref_5","first-page":"693","article-title":"Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes","volume":"53","author":"LUMENG, L.; Li, T.K.","year":"1974","unstructured":"LUMENG, L. & Li, T.K. (1974) Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes. Journal of Clinical Investigation, 53, 693.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_6","article-title":"Vitamin utilization status in chronic alcoholics","author":"MAJUMDAR, S.K.; SHAW, G.K.; THOMSON, A.D.","year":"1981","unstructured":"MAJUMDAR, S.K., SHAW, G.K. & THOMSON, A.D. (1981) Vitamin utilization status in chronic alcoholics. International Journal of Vitamin and Nutrition Research (Switzerland), (in press).","journal-title":"International Journal of Vitamin and Nutrition Research"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/00365521.1977.12031122","article-title":"Plasma pyridoxal phosphate levels in fulminant hepatic failure and the effects of parenteral supplementation","volume":"12","author":"Rossouw, J.E.; LABADARIOS, D.; MCCONNELL, J.B.; DAVIS, M.; WILLIAMS, R.","year":"1977","unstructured":"Rossouw, J.E., LABADARIOS, D., MCCONNELL, J.B., DAVIS, M. & WILLIAMS, R. (1977) Plasma pyridoxal phosphate levels in fulminant hepatic failure and the effects of parenteral supplementation. Scandinavian Journal of Gastroenterology, 12, 123.","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0300-595X(78)80026-7","article-title":"Alcohol and nutrition","volume":"7","author":"THOMSON, A.D.","year":"1978","unstructured":"THOMSON, A.D. (1978) Alcohol and nutrition. Clinics in Endocrinology and Metabolism, 7, 405.","journal-title":"Clinics in Endocrinology and Metabolism"},{"key":"ref_9","first-page":"447","article-title":"Mechanisms of brain damage in alcoholic liver disease","volume":"21","author":"THOMSON, A.D.; MAJUMDAR, S.K.; SHAW, G.K.; LISHMAN, W.A.; RON, M.; ACKER, W.","year":"1980","unstructured":"THOMSON, A.D., MAJUMDAR, S.K., SHAW, G.K., LISHMAN, W.A., RON, M. & ACKER, W. (1980a) Mechanisms of brain damage in alcoholic liver disease. Gut, 21, A.447.","journal-title":"Gut"},{"key":"ref_10","first-page":"103","article-title":"Malnutrition in the alcoholic. In: Medical Consequences of Alcohol Abuse, Ch","author":"THOMSON, A.D.; RAE, S.A.; MAJUMDAR, S.K.","year":"1980","unstructured":"THOMSON, A.D., RAE, S.A. & MAJUMDAR, S.K. (1980b) Malnutrition in the alcoholic. In: Medical Consequences of Alcohol Abuse, Ch. 6, pp. 103-155 (Ed by Clarke, P.M.S. & Kricka, L.J.). Ellis Horwood, Chichester (U.K.) (in press)."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/57\/665\/164\/50216196\/postgradmedj-57-164.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/57\/665\/164\/50216196\/postgradmedj-57-164.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T17:28:44Z","timestamp":1683739724000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/57\/665\/164\/7050264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,3,1]]},"references-count":10,"journal-issue":{"issue":"665","published-online":{"date-parts":[[1981,3,1]]},"published-print":{"date-parts":[[1981,3,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.57.665.164","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1981,3]]},"published":{"date-parts":[[1981,3,1]]}}}