{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:23:41Z","timestamp":1760189021382},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"668","license":[{"start":{"date-parts":[[1981,6,1]],"date-time":"1981-06-01T00:00:00Z","timestamp":360201600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,6,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>The case is reported of a man developing drug-induced systemic lupus erythematosus while taking hydralazine. The illness was characterized by arthritis and a purpuric rash particularly in the light-sensitive areas as well as orogenital and cutaneous ulceration. Anti-nuclear antibody and DNA binding were positive. All clinical manifestations disappeared on withdrawal of hydralazine.<\/jats:p>","DOI":"10.1136\/pgmj.57.668.378","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:43:59Z","timestamp":1230583439000},"page":"378-379","source":"Crossref","is-referenced-by-count":15,"title":["Orogenital ulcers, SLE and hydralazine"],"prefix":"10.1093","volume":"57","author":[{"given":"E","family":"Neville","sequence":"first","affiliation":[{"name":"Royal Victoria Infirmary , Newcastle upon Tyne NE1 4LP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P Y","family":"Graham","sequence":"additional","affiliation":[{"name":"Royal Victoria Infirmary , Newcastle upon Tyne NE1 4LP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R A L","family":"Brewis","sequence":"additional","affiliation":[{"name":"Royal Victoria Infirmary , Newcastle upon Tyne NE1 4LP"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1981,6,1]]},"reference":[{"key":"ref_1","first-page":"4204","article-title":"Association d'une maladie lupique et d'une maladie de Behcet","volume":"6","author":"DELRIEU, F.; JOB, C.H.; MARTIN, J.-L.; CHOURAKI, L.; DELBARRE, F.","year":"1977","unstructured":"DELRIEU, F., JOB, CH., MARTIN, J.-L., CHOURAKI, L. & DELBARRE, F. (1977) Association d'une maladie lupique et d'une maladie de Behcet. Nouvelle Press Medicale, 6, 4204.","journal-title":"Nouvelle Press Medicale"},{"key":"ref_2","first-page":"273","article-title":"Hydrallazine-induced lupus erythematosus-like syndrome in a patient of the rapid acetylator phenotype","volume":"2","author":"HARLAND, S.J.; FACCHINI, V.; TIMBRELL, J.A.","year":"1980","unstructured":"HARLAND, S.J., FACCHINI, V. & TIMBRELL, J.A. (1980) Hydrallazine-induced lupus erythematosus-like syndrome in a patient of the rapid acetylator phenotype. British Medical Journal, 2, 273.","journal-title":"British Medical Journal"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/0002-9343(73)90084-3","article-title":"Late toxicity to hydralazine resembling systemic lupus erythematosus or rheumatoid arthritis","volume":"54","author":"PERRY Jr, H. M","year":"1973","unstructured":"PERRY Jr, H.M. (1973) Late toxicity to hydralazine resembling systemic lupus erythematosus or rheumatoid arthritis. American Journal of Medicine, 54, 58.","journal-title":"American Journal of Medicine"},{"key":"ref_4","article-title":"Acetylator phenotype in patients with hydrallazineinduced lupoid syndrome","author":"STRANDBERG, I.; BOMAN, G.; HASSLER, L.; SJOQVIST, F.","year":"1976","unstructured":"STRANDBERG, I., BOMAN, G., HASSLER, L. & SJOQVIST, F. (1976) Acetylator phenotype in patients with hydrallazineinduced lupoid syndrome. Acta medica scandinavica, 200, 367.","journal-title":"Acta"},{"key":"ref_5","first-page":"387","article-title":"Drug-induced lupus erythematosus syndrome. Acta dermatologica","volume":"54","author":"ULLMAN, S.; WIIK, A.; KOBAYASI, T.; HALBERG, P.","year":"1974","unstructured":"ULLMAN, S., WIIK, A., KOBAYASI, T. & HALBERG, P. (1974) Drug-induced lupus erythematosus syndrome. Acta dermatologica. Stockholm, 54, 387.","journal-title":"Stockholm"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/57\/668\/378\/50216157\/postgradmedj-57-378.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/57\/668\/378\/50216157\/postgradmedj-57-378.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T19:17:22Z","timestamp":1683746242000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/57\/668\/378\/7050327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,6,1]]},"references-count":5,"journal-issue":{"issue":"668","published-online":{"date-parts":[[1981,6,1]]},"published-print":{"date-parts":[[1981,6,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.57.668.378","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1981,6]]},"published":{"date-parts":[[1981,6,1]]}}}