{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T20:03:27Z","timestamp":1699128207516},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"670","license":[{"start":{"date-parts":[[1981,8,1]],"date-time":"1981-08-01T00:00:00Z","timestamp":365472000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,8,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Pituitary function was assessed in 39 patients with previously untreated hyperprolactinaemia. Primary hypothyroidism, drug-induced hyperprolactinaemia and chronic renal failure were excluded in all patients. All of the 22 patients (group 1), who had either a normal pituitary fossa or a minor radiological change on lateral skull X-ray, had completely normal pituitary function with the exception of 2 who were partially growth hormone-deficient. However, 9 of the 17 patients with macroadenomas (group 2) had a deficit of one or more anterior pituitary hormones. After the lateral skull X-ray 13 patients in group 1 had further neuroradiological investigations. In only one was a minor abnormality noted which had not been observed on the plain film and this was not of practical significance.<\/jats:p>\n               <jats:p>In centres where hyperprolactinaemic patients with a normal pituitary fossa or a minor radiological change on lateral skull X-ray are treated with bromocriptine, further neuroradiological investigations and dynamic tests of pituitary function are not required.<\/jats:p>","DOI":"10.1136\/pgmj.57.670.485","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:43:59Z","timestamp":1230583439000},"page":"485-487","source":"Crossref","is-referenced-by-count":1,"title":["A practical approach to the investigation of the hyperprolactinaemic patient"],"prefix":"10.1093","volume":"57","author":[{"given":"S M","family":"Shalet","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Christie Hospital , Manchester"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A J","family":"Chapman","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Christie Hospital , Manchester"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Whitehead","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Christie Hospital , Manchester"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C G","family":"Beardwell","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Christie Hospital , Manchester"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1981,8,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.7326\/0003-4819-87-2-165","article-title":"Galactorrheamenorrhea syndrome: diagnosis and therapy","volume":"87","author":"BOYD, A.E.; REICHLIN, S.; TURKSOY, R.N.","year":"1977","unstructured":"BOYD, A.E., REICHLIN, S. & TURKSOY, R.N. 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HULL, M.G.R., STEELE, S.J. & NABARRO, J.D.N. (1976) Clinical and endocrine features of hyperprolactinemic amenorrhea."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1365-2265.1980.tb02719.x","article-title":"The importance of pituitary tumor size in patients with hyperprolactinemia in relation to hormonal variables and extrasellar extension in tumor","volume":"12","author":"KLUN, J.G.M.; LAMBERTS, S.W.J.; JONG, D.E.; H., F.; DOCTER, R.; DONGEN, V.A.N.; J., K.; BIRKENHAGER, J.C.","year":"1980","unstructured":"KLUN, J.G.M., LAMBERTS, S.W.J., DE JONG, F.H., DOCTER, R., VAN DONGEN, K.J. & BIRKENHAGER, J.C. (1980) The importance of pituitary tumor size in patients with hyperprolactinemia in relation to hormonal variables and extrasellar extension in tumor. 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American Journal of Obstetrics and Gynecology, 135, 467.","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1136\/jcp.15.4.374","article-title":"A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma","volume":"15","author":"MATTINGLY, D.","year":"1962","unstructured":"MATTINGLY, D, (1962) A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma. Journal of C4inical Pathology, 15, 374.","journal-title":"Journal of C4inical Pathology"},{"key":"ref_10","first-page":"104","article-title":"Pituitary function after treatment of intracranial tumours in children","volume":"ii,","author":"PEARSON, D.","year":"1975","unstructured":"PEARSON, D. (1975) Pituitary function after treatment of intracranial tumours in children. Lancet, ii, 104.","journal-title":"Lancet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1259\/0007-1285-48-569-366","article-title":"Borderline variants of the normal pituitary fossa","volume":"48","author":"SWANSON, H.A.; BOULAY, D.U.; G.","year":"1975","unstructured":"SWANSON, H.A. & DU BOULAY, G. (1975) Borderline variants of the normal pituitary fossa. British Journal of Radiology, 48, 366.","journal-title":"British Journal of Radiology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"46","DOI":"10.2214\/ajr.120.1.46","article-title":"Prolactin-secreting pituitary adenomas","volume":"120","author":"VEZINA, J.L.; J, S.U.T.T.O.N.T.","year":"1974","unstructured":"VEZINA, J.L. & SUTTON. T.J. (1974) Prolactin-secreting pituitary adenomas. 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