{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:52:16Z","timestamp":1777931536303,"version":"3.51.4"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"670","license":[{"start":{"date-parts":[[1981,8,1]],"date-time":"1981-08-01T00:00:00Z","timestamp":365472000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,8,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A case of Graves\u2019 disease with potassium perchorate for 22 years without ill effect is described. Thyrotoxicosis recurred 4 weeks after the medication was withdrawn, suggesting that euthyroidism had been maintained by chronic use of the drug. As toxicity of perchlorate is probably dose related, it is suggested that long-term use of low dose perchlorate may be no more hazardous than alternative antithyroid therapy.<\/jats:p>","DOI":"10.1136\/pgmj.57.670.516","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:43:59Z","timestamp":1230583439000},"page":"516-517","source":"Crossref","is-referenced-by-count":8,"title":["Long-term use of potassium perchlorate"],"prefix":"10.1093","volume":"57","author":[{"given":"J M C","family":"Connell","sequence":"first","affiliation":[{"name":"Department of Medicine, Western Infirmary , Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1981,8,1]]},"reference":[{"key":"ref_1","first-page":"453","article-title":"Fatal complications following use of potassium perchlorate in thyrotoxicosis","volume":"2","author":"BARZILAI, D.; SHEINFELD, M.","year":"1966","unstructured":"BARZILAI, D. & SHEINFELD, M. (1966) Fatal complications following use of potassium perchlorate in thyrotoxicosis. Israeli Journal of Medical Science, 2, 453.","journal-title":"Israeli Journal of Medical Science"},{"key":"ref_2","article-title":"Increase in thyrotoxicosis in an endemic goitre area after iodation of bread","volume":"500","author":"CONNOLLY, R.J.; VIDOR, G.I.; STEWART, J.C.","year":"1970","unstructured":"CONNOLLY, R.J., VIDOR, G.I. & STEWART, J.C. (1970) Increase in thyrotoxicosis in an endemic goitre area after iodation of bread. Lancet, i, 500.","journal-title":"Lancet"},{"key":"ref_3","article-title":"A comparison of potassium perchlorate, methylthiouracil and carbimazole in the treatment of thyrotoxicosis","volume":"401","author":"CROOKS, J.; WAYNE, E.J.","year":"1960","unstructured":"CROOKS, J. & WAYNE, E.J. (1960) A comparison of potassium perchlorate, methylthiouracil and carbimazole in the treatment of thyrotoxicosis. Lancet, i, 401.","journal-title":"Lancet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1210\/jcem-14-1-70","article-title":"Preliminary experience in the treatment of hyperthyroidism with potassium perchlorate","volume":"14","author":"GODLEY, A.F.; STANBURY, J.B.","year":"1954","unstructured":"GODLEY, A.F. & STANBURY, J.B. (1954) Preliminary experience in the treatment of hyperthyroidism with potassium perchlorate. Journal of Clinical Endocrinology, 14, 70.","journal-title":"Journal of Clinical Endocrinology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1136\/bmj.2.5205.1086-a","article-title":"Potassium perchlorate in thyrotoxicosis","volume":"2","author":"MORGANS, M.E.; TROTTER, W.R.","year":"1960","unstructured":"MORGANS, M.E. & TROTTER, W.R. (1960) Potassium perchlorate in thyrotoxicosis. British Medical Journal, 2, 1086.","journal-title":"British Medical Journal"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/57\/670\/516\/49290474\/postgradmedj-57-516.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/57\/670\/516\/49290474\/postgradmedj-57-516.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T13:24:38Z","timestamp":1681997078000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/57\/670\/516\/7050242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,8,1]]},"references-count":5,"journal-issue":{"issue":"670","published-online":{"date-parts":[[1981,8,1]]},"published-print":{"date-parts":[[1981,8,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.57.670.516","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1981,8]]},"published":{"date-parts":[[1981,8,1]]}}}