{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T06:06:55Z","timestamp":1760249215080},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"673","license":[{"start":{"date-parts":[[1981,11,1]],"date-time":"1981-11-01T00:00:00Z","timestamp":373420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,11,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Two patients are described in whom paradoxical embolism was diagnosed during life. One patient with cerebral embolism died and the other, with peripheral embolization, survived after treatment with streptokinase. Thrombolytic therapy has not previously been described in the treatment of patients with paradoxical embolism.<\/jats:p>","DOI":"10.1136\/pgmj.57.673.717","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:43:59Z","timestamp":1230583439000},"page":"717-718","source":"Crossref","is-referenced-by-count":10,"title":["Paradoxical embolism associated with patent foramen ovale"],"prefix":"10.1093","volume":"57","author":[{"given":"R C F","family":"Leonard","sequence":"first","affiliation":[{"name":"Department of Medicine, Royal Victoria Infirmary , Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Neville","sequence":"additional","affiliation":[{"name":"Department of Medicine, Royal Victoria Infirmary , Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R J C","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Royal Victoria Infirmary , Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1981,11,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1161\/01.CIR.53.3.564","article-title":"Paradoxical embolism: a diagnostic challenge and its detection during life","volume":"53","author":"CHENG, T.O.","year":"1976","unstructured":"CHENG, T.O. (1976) Paradoxical embolism: a diagnostic challenge and its detection during life. Circulation, 53, 565.","journal-title":"Circulation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1161\/01.STR.11.5.433","article-title":"Cerebral embolism of cardiac origin","volume":"2","author":"EASTON, J.D.; SHERMAN, D.G.","year":"1980","unstructured":"EASTON, J.D. & SHERMAN, D.G. (1980) Cerebral embolism of cardiac origin. Stroke, 2, 433.","journal-title":"Stroke"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1136\/hrt.39.10.1128","article-title":"Longterm prognosis of treated acute massive pulmonary embolism","volume":"39","author":"HALL, R.J.C.; SUTTON, G.C.; KERR, I.H.","year":"1977","unstructured":"HALL, R.J.C., SUTTON, G.C. & KERR, I.H. (1977) Longterm prognosis of treated acute massive pulmonary embolism. 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New England Journal of Medicine, 273, 1250.","journal-title":"New England Journal of Medicine"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/00000658-196804000-00020","article-title":"Paradoxical embolisation","volume":"167","author":"PADULA, R.T.; CAMISHION, R.C.","year":"1968","unstructured":"PADULA, R.T. & CAMISHION, R.C. (1968) Paradoxical embolisation. Annals of Surgery, 167, 598.","journal-title":"Annals of Surgery"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1056\/NEJM197307122890201","article-title":"Late prognosis of acute pulmonary embolism","volume":"289","author":"PARASKOS, J.A.; ADELSTEIN, S.J.; SMITH, R.E.; RICKMAN, F.D.; GROSSMAN, W.; DEXTER, L.; DALEN, J.E.","year":"1973","unstructured":"PARASKOS, J.A., ADELSTEIN, S.J., SMITH, R.E., RICKMAN, F.D., GROSSMAN, W., DEXTER, L. & DALEN, J.E. (1973) Late prognosis of acute pulmonary embolism. New England Journal of Medicine, 289, 55.","journal-title":"New England Journal of Medicine"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1136\/hrt.39.10.1135","article-title":"Clinical course and late prognosis of treated subacute massive, acute minor, and chronic pulmonary thrombo-embolism","volume":"39","author":"SUTTON, G.C.; HALL, R.J.C.; KERR, I.H.","year":"1977","unstructured":"SUTTON, G.C., HALL, R.J.C. & KERR, I.H. (1977) Clinical course and late prognosis of treated subacute massive, acute minor, and chronic pulmonary thrombo-embolism. British Heart Journal, 39, 1135.","journal-title":"British Heart Journal"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/qjmed\/os-23.90.135","article-title":"Paradoxical embolism","volume":"23","author":"THOMPSON, T.; EVANS, W.","year":"1930","unstructured":"THOMPSON, T. & EVANS, W. (1930) Paradoxical embolism. 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