{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:48:27Z","timestamp":1759009707828},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"683","license":[{"start":{"date-parts":[[1982,9,1]],"date-time":"1982-09-01T00:00:00Z","timestamp":399686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1982,9,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 70-year-old man with a history of chronic middle and external ear suppuration presenting with acute meningitis due to Bacteroides uniformis is described. Anaerobic organisms including Bacteroides species were cultured from the affected external auditory meatus. Administration of metronidazole led to complete clinical recovery and a cholesteatoma was subsequently surgically evacuated. Chronic suppuration in the middle ear and paranasal sinuses is the commonest primary cause of cerebral abscess and in this setting meningitis is associated with a particularly high mortality. The major role of anaerobic sepsis in otolaryngological practice is well established. Metronidazole is the chemotherapeutic agent of choice.<\/jats:p>","DOI":"10.1136\/pgmj.58.683.560","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:43:59Z","timestamp":1230583439000},"page":"560-561","source":"Crossref","is-referenced-by-count":4,"title":["Bacteroides meningitis complicating chronic mastoiditis"],"prefix":"10.1093","volume":"58","author":[{"given":"D","family":"Siegler","sequence":"first","affiliation":[{"name":"Department of Medicine and Public Health Laboratory, Luton and Dunstable Hospital , Luton, Beds"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M C","family":"Faiers","sequence":"additional","affiliation":[{"name":"Department of Medicine and Public Health Laboratory, Luton and Dunstable Hospital , Luton, Beds"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A T","family":"Willis","sequence":"additional","affiliation":[{"name":"Department of Medicine and Public Health Laboratory, Luton and Dunstable Hospital , Luton, Beds"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1982,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1017\/S0022215100089374","article-title":"A case of anaerobic middle ear infection with complications","volume":"94","author":"BEEDEN, A.G.; WILLIS, A.T.","year":"1980","unstructured":"BEEDEN, A.G. & WILLIS, A.T. (1980) A case of anaerobic middle ear infection with complications. Journal ofLaryngology and Otology, 94, 659.","journal-title":"Journal ofLaryngology and Otology"},{"key":"ref_2","doi-asserted-by":"crossref","DOI":"10.1016\/S0140-6736(77)92592-2","article-title":"Bacteroidesfragiis meningitis","author":"CHATTOPADHYAY, B.","year":"1977","unstructured":"CHATTOPADHYAY, B. (1977) Bacteroidesfragiis meningitis. Lancet, L 1371.","journal-title":"Lancet, L"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0002-9343(79)90394-2","article-title":"Anaerobic bacterial meningitis","volume":"67","author":"HEEREMA, M.S.; EIN, M.E.; MUSHER, D.M.; BRADSHAW, M.W.; WILLIAMS, T.W.","year":"1979","unstructured":"HEEREMA, M.S., EIN, M.E., MUSHER, D.M., BRADSHAW, M.W. & WILLIAMS, T.W. (1979) Anaerobic bacterial meningitis. American Journal of Medicine, 67, 219.","journal-title":"American Journal of Medicine"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1093\/jac\/2.3.224","article-title":"Cerebral abscess","volume":"2","author":"INGHAM, H.R.; SELKON, J.B.","year":"1976","unstructured":"INGHAM, H.R. & SELKON, J.B. (1976) Cerebral abscess. Journal of Antimicrobial Chemotherapy, 2, 224.","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1136\/bmj.2.6093.991","article-title":"Bacteriological study of otogenic cerebral abscesses: chemotherapeutic role of metronidazole","volume":"2","author":"INGHAM, H.R.; SELKON, J.B.; RoxBY, S.M.","year":"1977","unstructured":"INGHAM, H.R., SELKON, J.B. & RoxBY, S.M. (1977) Bacteriological study of otogenic cerebral abscesses: chemotherapeutic role of metronidazole. British Medical Journal, 2, 991.","journal-title":"British Medical Journal"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1136\/pgmj.56.655.351","article-title":"Primary meningitis caused by Bacteroides fragilis and Fusobacteium necrophorum","volume":"56","author":"ISLAM, A.K.M.S.; SHNEERSON, J.M.","year":"1980","unstructured":"ISLAM, A.K.M.S. & SHNEERSON, J.M. (1980) Primary meningitis caused by Bacteroides fragilis and Fusobacteium necrophorum. Postgraduate Medical Journal, 56, 351.","journal-title":"Postgraduate Medical Journal"},{"key":"ref_7","first-page":"389","article-title":"Intracranial abscesses: a review of treated patients over 20 years","volume":"46","author":"JEFFERSON, A.A.; KEOGH, A.J.","year":"1977","unstructured":"JEFFERSON, A.A. & KEOGH, A.J. (1977) Intracranial abscesses: a review of treated patients over 20 years. Quarterly Journal of Medicine, N.S. 46, 389.","journal-title":"Quarterly Journal of Medicine, N. S"},{"issue":"463","key":"ref_8","article-title":"Excellent outcome of Bacteroides meningitis in a newborn treated with metronidazole","volume":"66","author":"LAW, B.J.; MARKS, M.I.","year":"1980","unstructured":"LAW, B.J. & MARKS, M.I. (1980) Excellent outcome of Bacteroides meningitis in a newborn treated with metronidazole. Pediatrics, 66,463.","journal-title":"Pediatrics"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/ana.410060412","article-title":"Bacteroides meningitis successfully treated with metronidazole","volume":"6","author":"PETERSON, D.I.; VOORHEES, E.G.; ELDER, H.A.","year":"1979","unstructured":"PETERSON, D.I., VOORHEES, E.G. & ELDER, H.A. (1979) Bacteroides meningitis successfully treated with metronidazole. Annals of Neurology, 6, 364.","journal-title":"Annals of Neurology"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/58\/683\/560\/49289871\/postgradmedj-58-560.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/58\/683\/560\/49289871\/postgradmedj-58-560.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T13:27:28Z","timestamp":1681997248000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/58\/683\/560\/7050047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,9,1]]},"references-count":9,"journal-issue":{"issue":"683","published-online":{"date-parts":[[1982,9,1]]},"published-print":{"date-parts":[[1982,9,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.58.683.560","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1982,9]]},"published":{"date-parts":[[1982,9,1]]}}}