{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T08:18:47Z","timestamp":1765959527505},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"687","license":[{"start":{"date-parts":[[1983,1,1]],"date-time":"1983-01-01T00:00:00Z","timestamp":410227200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1983,1,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Four cases are described in which the drug mianserin was implicated in the development of leucopenia. In one case this was accompanied by fatal aplastic anaemia. In a second, generalized bone marrow depression occurred, although leucopenia was the only clinically significant manifestation. Mianserin may depress bone marrow function and haematological surveillance is appropriate for patients taking this drug.<\/jats:p>","DOI":"10.1136\/pgmj.59.687.31","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:43:59Z","timestamp":1230583439000},"page":"31-33","source":"Crossref","is-referenced-by-count":8,"title":["Blood dyscrasias and mianserin"],"prefix":"10.1093","volume":"59","author":[{"given":"P C","family":"Adams","sequence":"first","affiliation":[{"name":"Departments of Medicine and Haematology, Royal Victoria Infirmary, Newcastle upon Tyne , 1055 Great Western Road, Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Robinson","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Haematology, Royal Victoria Infirmary, Newcastle upon Tyne , 1055 Great Western Road, Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M M","family":"Reid","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Haematology, Royal Victoria Infirmary, Newcastle upon Tyne , 1055 Great Western Road, Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M C","family":"Vishu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cumberland Infirmary , Carlisle, 1055 Great Western Road, Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Livingston","sequence":"additional","affiliation":[{"name":"University Department of Psychological Medicine, Gartnavel Royal Hospital , 1055 Great Western Road, Glasgow"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1983,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.5694\/j.1326-5377.1980.tb131972.x","volume":"2","author":"(OF, ADVERSE DRUG REACTIONS ADVISORY COMMITTEE","year":"1980","unstructured":"ADVERSE DRUG REACTIONS ADVISORY COMMITTEE (OF AUSTRALIA) (1980) Medical Journal of Australia, 2, 673.","journal-title":"Medical Journal of Australia"},{"key":"ref_2","article-title":"COMMITTEE ON SAFETY OF MEDICINES","volume-title":"Personal Communication","year":"1981","unstructured":"COMMITTEE ON SAFETY OF MEDICINES (1981a) Personal Communication."},{"key":"ref_3","first-page":"1","article-title":"COMMITTEE ON SAFETY OF MEDICINES","volume":"7","year":"1981","unstructured":"COMMITTEE ON SAFETY OF MEDICINES (1981b) Mianserin and blood dyscrasias. Current Problems, 7, 1.","journal-title":"Current Problems; Mianserin and blood dyscrasias"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1136\/bmj.1.6160.378","article-title":"Mianserin and agranulocytosis","volume":"1","author":"A., C.U.R.S.O.N.D.; S, H.A.L.E.A.","year":"1979","unstructured":"CURSON. D.A. & HALE. A.S. (1979) Mianserin and agranulocytosis. British Medical Journal, 1, 378.","journal-title":"British Medical Journal"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1136\/bmj.1.6163.623-b","article-title":"Leucopenia in association with mianserin treatment","volume":"1","author":"M., McHARG A.; F, McHARG J.","year":"1979","unstructured":"McHARG. A.M. & McHARG. J.F. (1979) Leucopenia in association with mianserin treatment. British Medical Journal. 1, 623.","journal-title":"British Medical Journal"},{"key":"ref_6","article-title":"Accepted","year":"1982","unstructured":"(Accepted 7 April 1982)"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/59\/687\/31\/50200283\/postgradmedj-59-31.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/59\/687\/31\/50200283\/postgradmedj-59-31.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T10:57:28Z","timestamp":1683284248000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/59\/687\/31\/7038611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,1,1]]},"references-count":6,"journal-issue":{"issue":"687","published-online":{"date-parts":[[1983,1,1]]},"published-print":{"date-parts":[[1983,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.59.687.31","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1983,1]]},"published":{"date-parts":[[1983,1,1]]}}}