{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T20:14:01Z","timestamp":1769199241056,"version":"3.49.0"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"689","license":[{"start":{"date-parts":[[1983,3,1]],"date-time":"1983-03-01T00:00:00Z","timestamp":415324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1983,3,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Two months after a pericardectomy for constrictive pericarditis a 37-year-old man presented with diarrhoea, abdominal pain and weight loss. During the course of investigation he developed brisk rectal bleeding and emergency angiography revealed a bleeding site related to an area of abnormal vasculature in the caecum. At laparotomy, the small bowel was found to be inflamed and the mesenteric lymph nodes enlarged. The overall histological appearances, confirmed later on endoscopic duodenal biopsies, were those of Whipple\u2019s disease. His symptoms resolved promptly after starting tetracycline therapy.<\/jats:p>\n               <jats:p>The clinical features of Whipple\u2019s disease are protean and often bizarre. We report here a case where the diagnosis was made after the onset of profuse rectal bleeding.<\/jats:p>","DOI":"10.1136\/pgmj.59.689.194","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:43:59Z","timestamp":1230583439000},"page":"194-195","source":"Crossref","is-referenced-by-count":9,"title":["Constrictive pericarditis and intestinal haemorrhage due to Whipple\u2019s disease"],"prefix":"10.1093","volume":"59","author":[{"given":"T","family":"Crake","sequence":"first","affiliation":[{"name":"Gastroenterology Unit, Royal Victoria Infirmary and University of Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G I","family":"Sandle","sequence":"additional","affiliation":[{"name":"Gastroenterology Unit, Royal Victoria Infirmary and University of Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A J","family":"Crisp","sequence":"additional","affiliation":[{"name":"Gastroenterology Unit, Royal Victoria Infirmary and University of Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C O","family":"Record","sequence":"additional","affiliation":[{"name":"Gastroenterology Unit, Royal Victoria Infirmary and University of Newcastle upon Tyne"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1983,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1056\/NEJM198110223051708","article-title":"Whipple's disease presenting as aortic insufficiency","volume":"305","author":"BOSTWICK, D.G.; BENSCH, K.G.; BURKE, J.S.; BILLINGHAM, M.E.; MILLER, D.C.; SMITH, J.C.; KEREN, D.F.","year":"1981","unstructured":"BOSTWICK, D.G., BENSCH, K.G., BURKE, J.S., BILLINGHAM, M.E., MILLER, D.C., SMITH, J.C. & KEREN, D.F. (1981) Whipple's disease presenting as aortic insufficiency. New England Journal of Medicine, 305, 995.","journal-title":"New England Journal of Medicine"},{"key":"ref_2","first-page":"417","article-title":"Survival in Whipple's disease","volume":"1","author":"GIBB, W.E.; MALPAS, J.S.; PARRISH, J.A.","year":"1964","unstructured":"GIBB, W.E., MALPAS, J.S. & PARRISH, J.A. (1964) Survival in Whipple's disease. British Medical Journal, 1, 417.","journal-title":"British Medical Journal"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1001\/archinte.1969.00300160091015","article-title":"Whipple's disease with cardiac and renal abnormalities","volume":"123","author":"KRAUNZ, R.F.","year":"1969","unstructured":"KRAUNZ, R.F. (1969) Whipple's disease with cardiac and renal abnormalities. Archives of Internal Medicine, 123, 701.","journal-title":"Archives of Internal Medicine"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/00005792-197005000-00001","article-title":"Whipple's disease: A review of 19 patients from one hospital and a review of the literature since 1950","volume":"49","author":"MAIZEL, H.; RUFFIN, M.J.; DOBBINS, W.O.","year":"1970","unstructured":"MAIZEL, H., RUFFIN, M.J. & DOBBINS, W.O. (1970) Whipple's disease: A review of 19 patients from one hospital and a review of the literature since 1950. Medicine (Baltimore), 49, 175.","journal-title":"Medicine (Baltimore)"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1093\/brain\/88.1.137","article-title":"Cerebral complications of Whipple's Disease","volume":"88","author":"SMITH, W.T.; FRENCH, J.M.; GOTTSMAN, M.; SMITH, A.J.; WAKESMILLER, J.A.","year":"1965","unstructured":"SMITH, W.T., FRENCH, J.M., GOTTSMAN, M., SMITH, A.J. & WAKESMILLER, J.A. (1965) Cerebral complications of Whipple's Disease. Brain, 88, 137.","journal-title":"Brain"},{"key":"ref_6","article-title":"Accepted","year":"1982","unstructured":"(Accepted 2 July 1982)"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/59\/689\/194\/50200374\/postgradmedj-59-194.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/59\/689\/194\/50200374\/postgradmedj-59-194.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T10:48:38Z","timestamp":1683283718000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/59\/689\/194\/7038718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,3,1]]},"references-count":6,"journal-issue":{"issue":"689","published-online":{"date-parts":[[1983,3,1]]},"published-print":{"date-parts":[[1983,3,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.59.689.194","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1983,3]]},"published":{"date-parts":[[1983,3,1]]}}}