{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T23:58:42Z","timestamp":1697932722517},"reference-count":87,"publisher":"Oxford University Press (OUP)","issue":"700","license":[{"start":{"date-parts":[[1984,2,1]],"date-time":"1984-02-01T00:00:00Z","timestamp":444441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1984,2,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>A review of staging investigations in the preoperative evaluation of mediastinal involvement in primary bronchial carcinoma is presented.<\/jats:p><jats:p>The following conclusions are offered as guidelines for the use of mediastinal staging procedures in clinical practice:<\/jats:p><jats:p>Surgical staging methods have the over-riding advantage of superior specificity over indirect imaging techniques. Where 67Ga-imaging or CT scanning are not available, routine pre-operative mediastinoscopy or, when appropriate, mediastinotomy will identify most patients with non-resectable disease but this approach entails a high proportion of true negative examinations.<\/jats:p><jats:p>Radioisotope ventilation and perfusion lung imaging has no place in the pre-operative staging of lung cancer.<\/jats:p><jats:p>Where the techniques are available, 67Ga-imaging and CT scanning have a use in selecting patients for mediastinal exploration.<\/jats:p><jats:p>A negative mediastinal 67Ga scan or a negative CT examination suggest that mediastinal exploration will be unrewarding in the vast majority of cases and may be omitted prior to thoracotomy.<\/jats:p><jats:p>A positive mediastinal 67Ga scan or the demonstration of abnormal mediastinal nodes by CT is an indication for mediastinal exploration which, if negative should be followed by thoracotomy.<\/jats:p>","DOI":"10.1136\/pgmj.60.700.83","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:58:16Z","timestamp":1230584296000},"page":"83-91","source":"Crossref","is-referenced-by-count":4,"title":["Pre-operative mediastinal evaluation in primary bronchial carcinoma\u2014a review of staging investigations"],"prefix":"10.1093","volume":"60","author":[{"given":"John A.","family":"Elliott","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Western Infirmary , Glasgow GI1 6NT"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1984,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0003-4975(10)63476-5","article-title":"The importance of mediastinal lymph node invasion by pulmonary carcinoma in selection of patients for resection","volume":"25","author":"SMITH, A.B.B.E.Y.; R.","year":"1978","unstructured":"ABBEY SMITH, R. 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