{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T08:56:17Z","timestamp":1700729777657},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"702","license":[{"start":{"date-parts":[[1984,4,1]],"date-time":"1984-04-01T00:00:00Z","timestamp":449625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1984,4,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>We report the case of an elderly woman with primary Sjogren\u2019s syndrome and abnormal liver function tests indicative of primary biliary cirrhosis. She was found to have a raised serum angiotensin converting enzyme activity. We proceeded to study 21 further cases of Sjogren\u2019s syndrome to discover whether raised levels of this enzyme were a feature of Sjogren\u2019s syndrome. None of them had any features to suggested associated primary biliary cirrhosis. The cases included 12 with associated rheumatoid arthritis, two with systemic sclerosis, three with systemic lupus erythematosus and four with primary Sjogren\u2019s syndrome. In only two of these 21 patients was a raised serum angiotensin converting enzyme obtained, the elevation being modest. We conclude that a raised activity of the enzyme is not usually associated with primary or secondary Sjogren\u2019s syndrome, and that discovery of such an abnormality should prompt a search for an associated condition.<\/jats:p>","DOI":"10.1136\/pgmj.60.702.270","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:58:16Z","timestamp":1230584296000},"page":"270-271","source":"Crossref","is-referenced-by-count":5,"title":["Serum angiotensin converting enzyme in Sjogren\u2019s syndrome\u2014a case report and study of 21 further cases"],"prefix":"10.1093","volume":"60","author":[{"given":"N. Dianne","family":"Machin","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Wtittington Hospital , Highgate Hill, London N.19"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"Chard","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Wtittington Hospital , Highgate Hill, London N.19"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. W.","family":"Paice","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Wtittington Hospital , Highgate Hill, London N.19"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1984,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.7326\/0003-4819-79-1-31","article-title":"Features of Sjogren's syndrome in primary biliary cirrhosis","volume":"79","author":"ALARCON-SEGOVIA, D.; DIAZ-JOUANNEN, E.; FISHBEIN, E.","year":"1973","unstructured":"ALARCON-SEGOVIA, D., DIAZ-JOUANNEN, E. & FISHBEIN, E. (1973) Features of Sjogren's syndrome in primary biliary cirrhosis. 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Journal of Clinical Pathology, 21, 656.","journal-title":"Journal of Clinical Pathology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1093\/ajcp\/66.2.416","article-title":"A sensitive fluoremetric assay for serum angiotensin converting enzyme","volume":"66","author":"FRIEDLAND, J.; SILVERSTEIN, E.","year":"1976","unstructured":"FRIEDLAND, J. & SILVERSTEIN, E. (1976) A sensitive fluoremetric assay for serum angiotensin converting enzyme. American Journal of Clinical Pathology, 66, 416.","journal-title":"American Journal of Clinical Pathology"},{"key":"ref_5","first-page":"340","article-title":"Sicca complex","volume":"4","author":"GOLDING, P.L.; BROWN, R.; MASON, A.M.S.; TAYLOR, E.","year":"1970","unstructured":"GOLDING, P.L., BROWN, R., MASON, A.M.S. & TAYLOR, E. (1970) 'Sicca complex' in liver disease. British Medical Journal, 4, 340.","journal-title":"in liver disease. 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Annals of Internal Medicine, 93, 825.","journal-title":"Annals of Internal Medicine"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/0002-9343(82)90335-7","article-title":"Angiotensin converting enzyme in diseases of the liver","volume":"73","author":"MATSUKI, K.; SAKATA, T.","year":"1982","unstructured":"MATSUKI, K. & SAKATA, T. (1982) Angiotensin converting enzyme in diseases of the liver. American Journal of Medicine, 73, 549.","journal-title":"American Journal of Medicine"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"212","DOI":"10.7326\/0003-4819-92-2-212","article-title":"Sjogren's syndrome (sicca syndrome): current issues","volume":"92","author":"MOUTSOPOULos, H.M.; CHUSED, T.M.; MANN, D.L.; KLIPPEL, J.H.; FANCI, A.S.; FRANK, M.M.; LAWLEY, T.J.; HAMBURGER, M.I.","year":"1980","unstructured":"MOUTSOPOULos, H.M., CHUSED, T.M., MANN, D.L., KLIPPEL, J.H., FANCI, A.S., FRANK, M.M., LAWLEY, T.J. & HAMBURGER, M.I. (1980) Sjogren's syndrome (sicca syndrome): current issues. Annals of Internal Medicine, 92, 212.","journal-title":"Annals of Internal Medicine"},{"key":"ref_10","first-page":"1331","article-title":"Serum angiotensin converting enzyme in sarcoidosis and other granulomatous disorders","volume":"ii,","author":"STUDDY, P.; BIRD, R.; JAMES, G.D.; SHERLOCK, S.","year":"1978","unstructured":"STUDDY, P., BIRD, R., JAMES, G.D. & SHERLOCK, S. (1978) Serum angiotensin converting enzyme in sarcoidosis and other granulomatous disorders. Lancet, ii, 1331.","journal-title":"Lancet"},{"key":"ref_11","first-page":"54","article-title":"Serum angiotensin converting enzyme in sarcoidosis and other granulomatous disorders","volume":"5","author":"STUDDY, P.; BIRD, R.; JAMES, G.D.; SHERLOCK, S.","year":"1979","unstructured":"STUDDY, P., BIRD, R., JAMES, G.D. & SHERLOCK, S. (1979) Serum angiotensin converting enzyme in sarcoidosis and other granulomatous disorders. 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