{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T05:02:48Z","timestamp":1766466168038},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"706","license":[{"start":{"date-parts":[[1984,8,1]],"date-time":"1984-08-01T00:00:00Z","timestamp":460166400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1984,8,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>The authors present a 35-year-old male patient with renovascular hypertension caused by the stenosis of both renal arteries of the right kidney. Two years after the diagnosis of hypertension was made, an endarterectomy was performed but a successful correction of the upper stenotic artery was not achieved. During the next 2 years the hypertensive disease was uncontrollable with antihypertensive medications and gradually entered into a malignant phase. In addition to the atrophy of the right kidney, an adenoma of the left adrenal gland was revealed (19.75 g) which was operated on. Left adrenalectomy had only a transitory benefit on blood pressure level. Five months later an adenoma of the right adrenal gland was diagnosed and together with the ischaemic right kidney was operated on (right adrenalectomy and nephrectomy) which definitely cured the hypertension.<\/jats:p>\n               <jats:p>The chronological sequence of events and the course of the disease in the patient point to the possibility that long-standing hyper-reninaemia, due to renal ischaemia, may cause the development of multiple bilateral adrenocortical adenomas and that secondary aldosteronism may transform into primary.<\/jats:p>","DOI":"10.1136\/pgmj.60.706.533","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:58:16Z","timestamp":1230584296000},"page":"533-536","source":"Crossref","is-referenced-by-count":10,"title":["Renovascular hypertension associated with bilateral aldosteronoma"],"prefix":"10.1093","volume":"60","author":[{"given":"M. I.","family":"Vircburger","sequence":"first","affiliation":[{"name":"Department of Endocrinology , Yugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordana M.","family":"Prelevi\u0107","sequence":"additional","affiliation":[{"name":"Department of Endocrinology , Yugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Todorovi\u0107","sequence":"additional","affiliation":[{"name":"Medical Centre \u2018Dedinje\u2019 , Belgrade Yugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Boji\u0107","sequence":"additional","affiliation":[{"name":"Department of Pathology, City Clinic Hospital, Belgrade Department of Cardiovascular Surgery , Yugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ljiljana A.","family":"Peri\u0107","sequence":"additional","affiliation":[{"name":"Endocrine Laboratory Yugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Paunkovi\u0107","sequence":"additional","affiliation":[{"name":"Medical Centre Zaje\u010dar , Yugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1984,8,1]]},"reference":[{"key":"ref_1","article-title":"Hyponatraemic hypertensive syndrome with renal artery occlusion corrected by captopril","volume":"606","author":"ATKINSON, A.B.; DAVIES, D.L.; LECKIE, B.; MORTON, J.J.; BROWN, J.J.; FRASER, R.; LEVER, A.F.; ROBERTSON, J.I.S.","year":"1979","unstructured":"ATKINSON, A.B., DAVIES, D.L., LECKIE, B., MORTON, J.J., BROWN, J.J., FRASER, R., LEVER, A.F. & ROBERTSON, J.I.S. (1979) Hyponatraemic hypertensive syndrome with renal artery occlusion corrected by captopril. Lancet, ii, 606.","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/0002-9343(72)90053-8","article-title":"Adrenal mineralocorticoids causing hypertension","volume":"52","author":"BIGLIERI, E.G.; STOCKIGT, J.R.; SCHAMBELAN, M.","year":"1972","unstructured":"BIGLIERI, E.G., STOCKIGT, J.R. & SCHAMBELAN, M. (1972) Adrenal mineralocorticoids causing hypertension. American Journal of Medicine, 52, 623.","journal-title":"American Journal of Medicine"},{"key":"ref_3","article-title":"Severe hypertension in primary aldosteronism and good response to surgery","volume":"482","author":"CLARKE, D.; JOHNSTON, I.D.A.; WILKINSON, R.; HACKING, P.M.; HAGGITH, J.W.","year":"1979","unstructured":"CLARKE, D., JOHNSTON, I.D.A., WILKINSON, R., HACKING, P.M. & HAGGITH, J.W. (1979) Severe hypertension in primary aldosteronism and good response to surgery. Lancet, i, 482.","journal-title":"Lancet"},{"key":"ref_4","first-page":"125","article-title":"Suppression of plasma renin activity in primary aldosteronism (distinguishing primary from secondary aldosteronism in hypertensive disease)","volume":"190","author":"CONN, J.W.; COHEN, E.L.; ROVNER, D.R.","year":"1964","unstructured":"CONN, J.W., COHEN, E.L. & ROVNER, D.R. (1964) Suppression of plasma renin activity in primary aldosteronism (distinguishing primary from secondary aldosteronism in hypertensive disease). Journal of the American Medical Association, 190, 125.","journal-title":"Journal of the American Medical Association"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1530\/acta.0.XXXIII0375","article-title":"Conn's syndrome: the effect of amphenone","volume":"33","author":"HOET, J.J.; MOLINEAUX, L.","year":"1960","unstructured":"HOET, J.J. & MOLINEAUX, L. (1960) Conn's syndrome: the effect of amphenone. Acta endocrinologica, 33, 375.","journal-title":"Acta endocrinologica"},{"key":"ref_6","first-page":"612","article-title":"Hypertension caused by renal artery occlusion simulating primary aldosteronism","volume":"9","author":"LAIDLAW, J.C.; YENDT, E.R.; GORNERL, A.G.","year":"1960","unstructured":"LAIDLAW, J.C., YENDT, E.R. & GORNERL, A.G. (1960) Hypertension caused by renal artery occlusion simulating primary aldosteronism, Metabolism, 9, 612.","journal-title":"Metabolism"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/0002-9343(72)90054-X","article-title":"Renin, angiotensin and aldosterone in pathogenesis and management ofhypertensive vascular disease","volume":"52","author":"LARAGH, J.H.; BAER, L.; BRUNNER, H.R.; BUHLER, R.F.; SEALEY, J.; VAUGHAN, JR, E.D.","year":"1972","unstructured":"LARAGH, J.H., BAER, L., BRUNNER, H.R., BUHLER, R.F., SEALEY, J. & VAUGHAN, E.D., JR (1972) Renin, angiotensin and aldosterone in pathogenesis and management ofhypertensive vascular disease. American Journal of Medicine, 52, 633.","journal-title":"American Journal of Medicine"},{"key":"ref_8","first-page":"471","article-title":"The syndrome ofprimary aldosteronism, In: The Endocrine Function of the Human Adrenal Cortex","author":"MANTERO, F.; ARMANINI, D.; GION, M.; OPOCHER, G.","year":"1978","unstructured":"MANTERO, F., ARMANINI, D., GION, M. & OPOCHER, G. (1978) The syndrome ofprimary aldosteronism, In: The Endocrine Function of the Human Adrenal Cortex (Ed. V.H.T. James, M. Serio, G. Giusti and L. Martini), p. 471. Academic Press, London, New York, San Francisco."},{"key":"ref_9","first-page":"5","article-title":"Renal ischemia and aldosteronism","volume":"20","author":"MICIC, R.; ARSENUIEVIC, M.; PuRAC, Li; HOLCER, L.; CERNIC, M.; ADANJA, S.","year":"1967","unstructured":"MICIC, R., ARSENUIEVIC, M., PuRAC, Li., HOLCER, L., CERNIC, M. & ADANJA, S. (1967) Renal ischemia and aldosteronism. Acta Medica Yugoslavica, 20, 5.","journal-title":"Acta Medica Yugoslavica"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1365-2265.1980.tb03396.x","article-title":"Corticosterone secreting tumours: with and without renal artery stenosis","volume":"13","author":"MILLS, I.H.; COOK, R.F.; GALLEY, J.M.; EDWARDS, O.M.M.; TAIT, A.D.","year":"1980","unstructured":"MILLS, I.H., COOK, R.F., GALLEY, J.M., EDWARDS, OM.M. & TAIT, A.D. (1980) Corticosterone secreting tumours: with and without renal artery stenosis. Clinical Endocrinology, 13, 355.","journal-title":"Clinical Endocrinology"},{"key":"ref_11","first-page":"296","article-title":"'Primary secondary' or tertiary aldosteronism","author":"Ross, E.J.","year":"1975","unstructured":"Ross, EJ. (1975) 'Primary secondary' or tertiary aldosteronism. In: Aldosterone and aldosteronism (Ed. E.J. Ross, p. 296. Lloyd-Luke (Medical Books), London."},{"key":"ref_12","first-page":"79","article-title":"Adrenal disease","author":"WOLFSEN, A.R.; TUCK, M.; KAPLAN, S.","year":"1977","unstructured":"WOLFSEN, A.R., TUCK, M. & KAPLAN, S. (1977) Adrenal disease. In: Endocrine Pathophysiology (Ed. J.M. Hershman), p. 79."},{"key":"ref_13","article-title":"Accepted 5","year":"1983","unstructured":"(Accepted 5 July 1983)"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/60\/706\/533\/50201924\/postgradmedj-60-533.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/60\/706\/533\/50201924\/postgradmedj-60-533.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T08:12:07Z","timestamp":1683274327000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/60\/706\/533\/7048066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,8,1]]},"references-count":13,"journal-issue":{"issue":"706","published-online":{"date-parts":[[1984,8,1]]},"published-print":{"date-parts":[[1984,8,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.60.706.533","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1984,8]]},"published":{"date-parts":[[1984,8,1]]}}}