{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:33:01Z","timestamp":1791286381599,"version":"4.1.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"713","license":[{"start":{"date-parts":[[1985,3,1]],"date-time":"1985-03-01T00:00:00Z","timestamp":478483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1985,3,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A fatal case of Ehlers-Danlos syndrome (Type IV) is described. Autopsy revealed splenic rupture that had resulted from spontaneous haemorrhage into the splenic parenchyma. This is a previously unrecorded complication of Ehlers-Danlos syndrome and should be considered in the differential diagnosis of chest and abdominal pain in patients with this condition.<\/jats:p>","DOI":"10.1136\/pgmj.61.713.259","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:58:16Z","timestamp":1230584296000},"page":"259-260","source":"Crossref","is-referenced-by-count":20,"title":["Fatal splenic rupture in Ehlers-Danlos syndrome"],"prefix":"10.1093","volume":"61","author":[{"given":"S C","family":"Harris","sequence":"first","affiliation":[{"name":"Royal Hallamshire Hospital , Sheffield"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D N","family":"Slater","sequence":"additional","affiliation":[{"name":"Royal Hallamshire Hospital , Sheffield"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C A","family":"Austin","sequence":"additional","affiliation":[{"name":"Royal Hallamshire Hospital , Sheffield"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1985,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/bjs.1800540107","article-title":"Ehlers-Danlos syndrome causing intestinal perforation","volume":"54","author":"ALDRIDGE, R.T.","year":"1967","unstructured":"ALDRIDGE, R.T. (1967). Ehlers-Danlos syndrome causing intestinal perforation. British Journal of Surgery, 54, 22.","journal-title":"British Journal of Surgery"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1136\/bmj.3.5564.558-b","article-title":"Ehlers-Danlos syndrome","volume":"3","author":"BANNERMAN, R.M.; GRAF, C.J.; UPSON, J.F.","year":"1967","unstructured":"BANNERMAN, R.M., GRAF, C.J. & UPSON, J.F. (1967). Ehlers-Danlos syndrome. British Medical Journal, 3, 558.","journal-title":"British Medical Journal"},{"key":"ref_3","first-page":"50","article-title":"The Ehlers-Danlos Syndrome","author":"BEIGHTON, P.","year":"1970","unstructured":"BEIGHTON, P. (1970). The Ehlers-Danlos Syndrome. 1st Edition p. 50, William Heinemann: London.","edition":"1st Edition"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0046-8177(82)80112-3","article-title":"Molecular pathology in inherited disorders of collagen metabolism","volume":"13","author":"BYERS, P.H.; BARSH, G.S.; HOLBROOK, K.A.","year":"1982","unstructured":"BYERS, P.H., BARSH, G.S. & HOLBROOK, K.A. (1982). Molecular pathology in inherited disorders of collagen metabolism. Human Pathology, 13, 89.","journal-title":"Human Pathology"},{"key":"ref_5","first-page":"336","article-title":"Altered secretion of Type III procollagen in a form of type IV Ehlers-Danlos syndrome. Biochemical studies in cultured fibroblasts","volume":"44","author":"BORNSTEIN, P.","year":"1981","unstructured":"BORNSTEIN, P. (1981). Altered secretion of Type III procollagen in a form of type IV Ehlers-Danlos syndrome. Biochemical studies in cultured fibroblasts. Laboratory Investigations, 44, 336.","journal-title":"Laboratory Investigations"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/0002-9343(69)90210-1","article-title":"Ehlers-Danlos syndrome with multiple arterial lesions","volume":"47","author":"IMAHORI, S.; BANNERMAN, P.M.; GRAF, C.J.; BRENNAN, J.C.","year":"1969","unstructured":"IMAHORI, S., BANNERMAN, P.M., GRAF, C.J. & BRENNAN, J.C. (1969). Ehlers-Danlos syndrome with multiple arterial lesions. American Journal of Medicine, 47, 967.","journal-title":"American Journal of Medicine"},{"key":"ref_7","article-title":"Ehlers-Danlos syndrome and 'congenital' arteriovenous fistulae. A clinicopathological study of a family","author":"LYNCH, H.T.; LARSEN, A.L.W.I.L.S.O.N.; R.; MAGNUSON, C.L.","year":"1965","unstructured":"LYNCH, H.T., LARSEN, A.L. WILSON, R. & MAGNUSON, C.L. (1965). Ehlers-Danlos syndrome and 'congenital' arteriovenous fistulae. A clinicopathological study of a family. 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Mosby: St Louis.","edition":"4th edition"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1073\/pnas.72.4.1314","article-title":"Patients with Ehlers-Danlos syndrome Type IV lack Type III collagen","volume":"72","author":"POPE, F.M.; MARTIN, G.M.; LICHTENSTEIN, J.R.; PENTIN-NEN, R.; GERSON, B.; ROWE, D.W.; McKUSICK, V.A.","year":"1975","unstructured":"POPE, F.M., MARTIN, G.M., LICHTENSTEIN, J.R., PENTIN-NEN, R., GERSON, B., ROWE, D.W. & McKUSICK, V.A. (1975). Patients with Ehlers-Danlos syndrome Type IV lack Type III collagen. 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