{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T17:59:34Z","timestamp":1769968774983,"version":"3.49.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"717","license":[{"start":{"date-parts":[[1985,7,1]],"date-time":"1985-07-01T00:00:00Z","timestamp":489024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1985,7,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 43 year old patient with Addison's disease secondary to extensive metastases to both adrenal glands is presented. Thirty two previously reported cases are reviewed; in only 13 cases was the diagnosis of Addison's disease confirmed biochemically. Reasons for the apparent rarity of Addison's disease in spite of the frequency of adrenal metastases are discussed. The need to consider the possibility of Addison's disease complicating known malignant disease arising in other tissues is stressed.<\/jats:p>","DOI":"10.1136\/pgmj.61.717.637","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:58:16Z","timestamp":1230584296000},"page":"637-639","source":"Crossref","is-referenced-by-count":13,"title":["Addison's disease due to metastases to the adrenal glands"],"prefix":"10.1093","volume":"61","author":[{"given":"F","family":"Mor","sequence":"first","affiliation":[{"name":"Department of Internal Medicine B, Beilinson Medical Center , Petah Tiqva, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Lahav","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine B, Beilinson Medical Center , Petah Tiqva, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Kipper","sequence":"additional","affiliation":[{"name":"Radiology Department, Beilinson Medical Center , Petah Tiqva, Israel"},{"name":"The Sackler Faculty of Medicine, Tel Aviv University , Ramat Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A J","family":"Wysenbeek","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine B, Beilinson Medical Center , Petah Tiqva, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1985,7,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/1097-0142(1950)3:1<74::AID-CNCR2820030111>3.0.CO;2-7","article-title":"Metastases in carcinoma. Analysis of 1000 autopsied cases","volume":"3","author":"ABRAMS, H.L.; SPIRO, R.; GOLDSTEIN, N.","year":"1950","unstructured":"ABRAMS, H.L., SPIRO, R. & GOLDSTEIN, N. (1950). Metastases in carcinoma. Analysis of 1000 autopsied cases. Cancer, 3, 74.","journal-title":"Cancer"},{"key":"ref_2","first-page":"244","article-title":"On the constitutional and local effects of disease of the suprarenal capsules. S","volume":"2","author":"ADDISON, T.","year":"1855","unstructured":"ADDISON, T. (1855). On the constitutional and local effects of disease of the suprarenal capsules. S. Highley: London, Reprinted in Medical Classics (1937) 2, 244."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"464","DOI":"10.7326\/0003-4819-57-3-464","article-title":"Addison's disease secondary to carcinoma of the breast","volume":"57","author":"ALPERS, D.H.; ENGELMAN, K.; FOLEY, F.D.","year":"1962","unstructured":"ALPERS, D.H., ENGELMAN, K. & FOLEY, F.D. (1962). Addison's disease secondary to carcinoma of the breast. Annals of Internal Medicine, 57, 464.","journal-title":"Annals of Internal Medicine"},{"key":"ref_4","first-page":"521","article-title":"Metastatic carcinoma of the adrenal glands","volume":"226","author":"BULLOCK, W.K.; HIRST, A.E.","year":"1953","unstructured":"BULLOCK, W.K. & HIRST, A.E. JR (1953). Metastatic carcinoma of the adrenal glands. American Journal of the Medical Sciences, 226, 521.","journal-title":"JR"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"930","DOI":"10.7326\/0003-4819-37-5-930","article-title":"Addison's disease secondary to metastatic carcinoma of the adrenal glands","volume":"37","author":"BUTTERLY, J.M.; FISHMAN, L.; SECKLER, J.; STEINBERG, H.","year":"1952","unstructured":"BUTTERLY, J.M., FISHMAN, L., SECKLER, J. & STEINBERG, H. (1952). Addison's disease secondary to metastatic carcinoma of the adrenal glands. Annals of Internal Medicine, 37, 930.","journal-title":"Annals of Internal Medicine"},{"key":"ref_6","first-page":"607","article-title":"The clinical significance of metastases to the adrenal glands","volume":"152","author":"CEDERMARK, B.J.; SJOBERG, H.E.","year":"1981","unstructured":"CEDERMARK, B.J. & SJOBERG, H.E. (1981). The clinical significance of metastases to the adrenal glands. Surgery, Gynecology and Obstetrics, 152, 607.","journal-title":"Surgery, Gynecology and Obstetrics"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1136\/bmj.2.6033.455","article-title":"Hodgkin's disease presenting with hypoadrenalism","volume":"2","author":"FEINMANN, C.; GILLET, R.; IRVING, M.H.","year":"1976","unstructured":"FEINMANN, C., GILLET, R. & IRVING, M.H. (1976). Hodgkin's disease presenting with hypoadrenalism. British Medical Journal, 2, 455.","journal-title":"British Medical Journal"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0002-9343(60)90233-3","article-title":"Addison's disease secondary to adrenocortical destruction by metastatic carcinoma of the breast","volume":"28","author":"GALLOWAY, J.A.; PERLOFF, W.H.","year":"1960","unstructured":"GALLOWAY, J.A. & PERLOFF, W.H. (1960). Addison's disease secondary to adrenocortical destruction by metastatic carcinoma of the breast. American Journal of Medicine, 28, 156.","journal-title":"American Journal of Medicine"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1158\/ajc.1938.57","article-title":"The incidence of metastasis of malignant tumours to the adrenals","volume":"32","author":"GLOMSET, P.H.","year":"1938","unstructured":"GLOMSET, P.H. (1938). The incidence of metastasis of malignant tumours to the adrenals. American Journal of Cancer, 32, 57.","journal-title":"American Journal of Cancer"},{"key":"ref_10","first-page":"742","article-title":"Addison's disease, a statistical analysis of 566 cases and a study ofthe pathology","volume":"10","author":"GUTTMAN, P.H.","year":"1930","unstructured":"GUTTMAN, P.H. (1930). Addison's disease, a statistical analysis of 566 cases and a study ofthe pathology. Archives of Pathology, 10, 742.","journal-title":"Archives of Pathology"},{"key":"ref_11","first-page":"545","article-title":"Adrenal insufficiency resulting from metastasis of non functioning adrenocortical carcinoma. MedicalAnnals ofthe District of","volume":"42","author":"HEATH, III, H.; BERGEUIN, P.R.","year":"1973","unstructured":"HEATH, H. III & BERGEUIN, P.R. (1973). Adrenal insufficiency resulting from metastasis of non functioning adrenocortical carcinoma. MedicalAnnals ofthe District of Columbia, 42, 545.","journal-title":"Columbia"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1002\/1097-0142(196611)19:11<1754::AID-CNCR2820191144>3.0.CO;2-N","article-title":"Addison's disease secondary to occult metastatic seminoma","volume":"19","author":"HERISON, J.C.","year":"1966","unstructured":"HERISON, J.C. (1966). Addison's disease secondary to occult metastatic seminoma. Cancer, 19, 1754.","journal-title":"Cancer"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1002\/1097-0142(196511)18:11<1467::AID-CNCR2820181116>3.0.CO;2-Q","article-title":"Adrenal insufficiency due to metastatic carcinoma of the lung","volume":"18","author":"HILL, II, G.J.; WHEELER, H.B.","year":"1965","unstructured":"HILL, G.J. II & WHEELER, H.B. (1965). Adrenal insufficiency due to metastatic carcinoma of the lung. 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British Medical Journal, 1, 1591.","journal-title":"British Medical Journal"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1002\/1097-0142(195411)7:6<1242::AID-CNCR2820070615>3.0.CO;2-R","article-title":"Metastatic carcinoma to the adrenal glands with cortical hypofunction","volume":"7","author":"SAHAGIAN-EDWARDS, A.; HOLLAND, J.F.","year":"1954","unstructured":"SAHAGIAN-EDWARDS, A. & HOLLAND, J.F. (1954). Metastatic carcinoma to the adrenal glands with cortical hypofunction. Cancer, 7, 1242.","journal-title":"Cancer"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1002\/1097-0142(197305)31:5<1240::AID-CNCR2820310531>3.0.CO;2-0","article-title":"Addison's disease secondary to metastatic carcinoma: an example of adrenocortical and adrenomedullary insufficiency","volume":"31","author":"VIEWEG, W.V.R.; REITZ, R.E.; WEINSTEIN, R.L.","year":"1973","unstructured":"VIEWEG, W.V.R., REITZ, R.E. & WEINSTEIN, R.L. (1973). Addison's disease secondary to metastatic carcinoma: an example of adrenocortical and adrenomedullary insufficiency. Cancer, 31, 1240.","journal-title":"Cancer"},{"key":"ref_18","first-page":"374","article-title":"In Pathology of Tumors","author":"WILLIS, R.A.","year":"1953","unstructured":"WILLIS, R.A. (1953). In Pathology of Tumors. p. 374. V.V. Mosby: St Louis."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1097\/00007611-198108000-00040","article-title":"Addison's disease as the sole clinical manifestation ofrecurrent bronchogenic carcinoma","volume":"74","author":"ZIMM, S.; GARDNER, D.F.; WALSH, J.W.; MAINE, C.P.; FERGUSON, R.H.; SMITH, W.K.","year":"1981","unstructured":"ZIMM, S., GARDNER, D.F., WALSH, J.W., MAINE, C.P., FERGUSON, R.H. & SMITH, W.K. (1981). Addison's disease as the sole clinical manifestation ofrecurrent bronchogenic carcinoma. Southern Medical Journal, 74, 1016.","journal-title":"Southern Medical Journal"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/61\/717\/637\/50155790\/postgradmedj-61-637.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/61\/717\/637\/50155790\/postgradmedj-61-637.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T13:04:08Z","timestamp":1683205448000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/61\/717\/637\/7046954"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,7,1]]},"references-count":19,"journal-issue":{"issue":"717","published-online":{"date-parts":[[1985,7,1]]},"published-print":{"date-parts":[[1985,7,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.61.717.637","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1985,7]]},"published":{"date-parts":[[1985,7,1]]}}}