{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:40:31Z","timestamp":1760298031284},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"726","license":[{"start":{"date-parts":[[1986,4,1]],"date-time":"1986-04-01T00:00:00Z","timestamp":512697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1986,4,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Two brothers with Fabry's disease presenting with palpitations were found to have intermittent supraventricular tachycardias. Their electrocardiograms, when symptom-free, revealed short PR intervals consistent with ventricular pre-excitation. Treatment of one of the brothers with verapamil resulted in improvement of the palpitations and reduction in frequency of the tachycardia. Recurrent supraventricular tachycardia associated with ventricular pre-excitation has not previously been described in Fabry's disease. Evidence suggests that this complication may be due to glycolipid deposition in the conducting system around the atrioventricular node.<\/jats:p>","DOI":"10.1136\/pgmj.62.726.285","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:58:16Z","timestamp":1230584296000},"page":"285-287","source":"Crossref","is-referenced-by-count":14,"title":["Short PR intervals and tachyarrhythmias in Fabry's disease"],"prefix":"10.1093","volume":"62","author":[{"given":"J","family":"Efthimiou","sequence":"first","affiliation":[{"name":"Department of Medicine, University College Hospital , London WC1E 6JJ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"McLelland","sequence":"additional","affiliation":[{"name":"Department of Medicine, University College Hospital , London WC1E 6JJ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D J","family":"Betteridge","sequence":"additional","affiliation":[{"name":"Department of Medicine, University College Hospital , London WC1E 6JJ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1986,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0002-9149(73)91037-0","article-title":"Electrophysiological studies in the syndrome of short PR interval, normal QRS complex","volume":"31","author":"CARACTA, A.R.; DAMATA, A.N.; GALLAGHER, J.J.; JOSEPHSON, M.E.; VARGESE, P.J.; LAU, S.H.; WESTURA, E.E.","year":"1973","unstructured":"CARACTA, A.R., DAMATA, A.N., GALLAGHER, J.J., JOSEPHSON, M.E., VARGESE, P.J., LAU, S.H. & WESTURA, E.E. (1973). Electrophysiological studies in the syndrome of short PR interval, normal QRS complex. American Journal of Cardiology, 31, 245.","journal-title":"American Journal of Cardiology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1056\/NEJM198210073071505","article-title":"Hypertrophic cardiomyopathy due to Fabry's disease","volume":"307","author":"COLUCCI, W.S.; LORELL, B.H.; SHOEN, F.J.W.A.R.H.O.L.; J., M.; GROSSMAN, W.C.","year":"1982","unstructured":"COLUCCI, W.S., LORELL, B.H., SHOEN, F.J. WARHOL, M.J. & GROSSMAN, W.C. (1982). Hypertrophic cardiomyopathy due to Fabry's disease. New England Journal ofMedicine, 307, 926.","journal-title":"New England Journal ofMedicine"},{"key":"ref_3","first-page":"95","article-title":"Fabry's disease: galactosidase A deficiency. In The Metabolic Basis of Inherited Disease","volume":"24","author":"DESNICK, R.J.; SWEELEY, C.C.","year":"1983","unstructured":"DESNICK, R.J. & SWEELEY, C.C. (1983). Fabry's disease: galactosidase A deficiency. In The Metabolic Basis of Inherited Disease, Stanbury, J.B., Wyngaarden, J.B., Fredrickson, D.S., Goldstein, J.L. & Brown, M.S. (eds), 5th ed. p. 906, McGraw-Hill: New York. FERRANS, V.J., HIBBS, R.G. & BURDA, C.D. (1969). The heart in Fabry's disease: a histochemical and electron microscopic study. American Journal of Cardiology, 24, 95.","edition":"5th ed","journal-title":"American Journal of Cardiology; The heart in Fabry's disease: a histochemical and electron microscopic study"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/0002-8703(61)90664-0","article-title":"Morphology of the human atrioventricular node with remarks pertinent to it's electrophysiology","volume":"61","author":"JAMES, T.N.","year":"1961","unstructured":"JAMES, T.N. (1961). Morphology of the human atrioventricular node with remarks pertinent to it's electrophysiology. American Heart Journal, 61, 756.","journal-title":"American Heart Journal"},{"key":"ref_5","first-page":"1112","article-title":"Glycogen storage disease of the heart","volume-title":"Heart Disease in Infancy and","author":"KEITH, J.; ROWE, R.; VLAD, P.","year":"1967","unstructured":"KEITH, J., ROWE, R. & VLAD, P. (1967). Glycogen storage disease of the heart. In Heart Disease in Infancy and Childhood, Keith, J. (ed), 2nd ed. p. 1112. Macmillan: New York.","edition":"2nd ed"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1161\/01.CIR.5.5.693","article-title":"The syndrome of short PR interval, normal QRS complex and paroxysmal rapid heart action","volume":"5","author":"LOWN, B.; GANONG, W.F.; LEVINE, S.A.","year":"1952","unstructured":"LOWN, B., GANONG, W.F. & LEVINE, S.A. (1952). The syndrome of short PR interval, normal QRS complex and paroxysmal rapid heart action. Circulation, 5, 693.","journal-title":"Circulation"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1177\/000331977802900709","article-title":"Accelerated atrioventricular conduction in Fabry's disease: a case report","volume":"29","author":"ROWE, J.W.; CARALIS, D.G.","year":"1978","unstructured":"ROWE, J.W. & CARALIS, D.G. (1978). Accelerated atrioventricular conduction in Fabry's disease: a case report. Angiology, 29, 562.","journal-title":"Angiology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1136\/hrt.40.10.1127","article-title":"Reentrant tachycardia using two bypass tracts and excluding AV node, in short PR interval, normal QRS syndrome","volume":"40","author":"WARD, D.E.; CAMM, A.J.; SPURRELL, R.A.","year":"1978","unstructured":"WARD, D.E., CAMM, A.J. & SPURRELL, R.A. (1978). Reentrant tachycardia using two bypass tracts and excluding AV node, in short PR interval, normal QRS syndrome. British Heart Journal, 40, 1127.","journal-title":"British Heart Journal"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/62\/726\/285\/50157129\/postgradmedj-62-285.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/62\/726\/285\/50157129\/postgradmedj-62-285.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T11:45:47Z","timestamp":1683200747000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/62\/726\/285\/7042862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,4,1]]},"references-count":8,"journal-issue":{"issue":"726","published-online":{"date-parts":[[1986,4,1]]},"published-print":{"date-parts":[[1986,4,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.62.726.285","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1986,4]]},"published":{"date-parts":[[1986,4,1]]}}}