{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T22:30:54Z","timestamp":1723761054371},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"727","license":[{"start":{"date-parts":[[1986,5,1]],"date-time":"1986-05-01T00:00:00Z","timestamp":515289600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1986,5,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>During a 10 year period 49 patients were recorded as having pulmonary infection caused by opportunist mycobacteria. Six different species were identified of which M. kansasii (65%) and M. avium-intracellulare (20%) were the most common. Cough and sputum (82%) or haemoptysis (26%) were frequent symptoms on presentation and over two thirds of patients had pre-existing respiratory disease. Chest radiographs showed predominantly apical disease with the right apex (44%) being twice as commonly affected as the left (22%). In 30% the radiograph showed bilateral disease.<\/jats:p>\n               <jats:p>Clinicians had an individual approach to treatment with no uniform pattern of drug prescribing. A majority of patients (59%) received rifampicin for at least 9 months and those patients with M. kansasii infection responded well with no bacteriological relapses in 20 patients followed for a mean period of 3.9 years. M. avium-intracellulare, M. malmoense and M. xenopi were less responsive to treatment and in four patients receiving chemotherapy death was attributed to mycobacterial infection.<\/jats:p>","DOI":"10.1136\/pgmj.62.727.363","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:58:16Z","timestamp":1230584296000},"page":"363-368","source":"Crossref","is-referenced-by-count":3,"title":["Pulmonary infection with opportunist mycobacteria on Merseyside 1974\u20131983"],"prefix":"10.1093","volume":"62","author":[{"given":"H W","family":"Clague","sequence":"first","affiliation":[{"name":"Chest Diseases Unit and Public Health Laboratory Service, Fazakerley Hospital , Longmoor Lane, Liverpool, L9 7AL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E H","family":"El-Ansary","sequence":"additional","affiliation":[{"name":"Chest Diseases Unit and Public Health Laboratory Service, Fazakerley Hospital , Longmoor Lane, Liverpool, L9 7AL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C A","family":"Hopkins","sequence":"additional","affiliation":[{"name":"Chest Diseases Unit and Public Health Laboratory Service, Fazakerley Hospital , Longmoor Lane, Liverpool, L9 7AL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Roberts","sequence":"additional","affiliation":[{"name":"Chest Diseases Unit and Public Health Laboratory Service, Fazakerley Hospital , Longmoor Lane, Liverpool, L9 7AL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1986,5,1]]},"reference":[{"key":"ref_1","first-page":"273","article-title":"Ventilatory defects in atypical mycobacteriosis","volume":"113","author":"AHN, C.H.; NASH, D.R.; HURST, G.A.","year":"1976","unstructured":"AHN, C.H., NASH, D.R. & HURST, G.A. 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Pulmonary infection with Mycobacterium kansasii in Wales, (1970-9): review of treatment and response. Thorax, 38, 271.","journal-title":"Thorax; of treatment and response"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1136\/thx.39.5.376","article-title":"Pulmonary infection with Myobacterium xenopi: a review oftreatment and response","volume":"39","author":"SMITH, A.P.","year":"1984","unstructured":"SMITH, A.P. (1984). Pulmonary infection with Myobacterium xenopi: a review oftreatment and response. Thorax, 39, 376.","journal-title":"Thorax"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0041-3879(75)90085-9","article-title":"Opportunist mycobacterial pulmonary infection and occupational dust exposure: an investigation in England and Wales","volume":"56","unstructured":"Opportunist mycobacterial pulmonary infection and occupational dust exposure: an investigation in England and Wales. 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Bulletin of the International Union of Tuberculosis, 29, 295.","journal-title":"Bulletin of the International Union of Tuberculosis"},{"key":"ref_15","first-page":"39","article-title":"A comparative study of tuberculous and other mycobacterial infections and their associations with malignancy","volume":"117","author":"ORTBALS, D.W.; MARR, J.J.","year":"1978","unstructured":"ORTBALS, D.W. & MARR, J.J. (1978). A comparative study of tuberculous and other mycobacterial infections and their associations with malignancy. American Review of Respiratory Disease, 117, 39.","journal-title":"American Review of Respiratory Disease"},{"key":"ref_16","author":"ROBERTS, C.; CLAGUE, H.W.; JENKINS, P.A.","year":"1985","unstructured":"ROBERTS, C., CLAGUE, H.W. & JENKINS, P.A. (1985)."},{"key":"ref_17","first-page":"265","article-title":"Regional lung function in asymptomatic cigarette smokers","volume":"118","author":"SEATON, D.; OGILVIE, C.","year":"1978","unstructured":"SEATON, D. & OGILVIE, C. 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American Review of Respiratory Disease, 119, 107.","journal-title":"American Review of Respiratory Disease"},{"key":"ref_20","article-title":"A study of diseases caused by atypical mycobacteria in","author":"YAMAMOTA, M.; SUDO, K.; TAGA, M.; HIBINO, S.","year":"1967","unstructured":"YAMAMOTA, M., SUDO, K., TAGA, M., HIBINO, S. (1967). A study of diseases caused by atypical mycobacteria in"},{"key":"ref_21","author":"ZVETINA, J.R.; DEMOS, T.C.; MALIWAN, N.; DRUNEN, M.V.; FREDERICK, W.; LETINO, J.; MODH, A.M.","year":"1984","unstructured":"ZVETINA, J.R., DEMOS, T.C., MALIWAN, N., DRUNEN, M.V., FREDERICK, W., LETINO, J. & MODH, A.M. (1984)."},{"key":"ref_22","first-page":"127","article-title":"Pulmonary cavitations in Mycobacterium kansasii, distinctions from M. tuberculosis","volume":"143","unstructured":"Pulmonary cavitations in Mycobacterium kansasii, distinctions from M. tuberculosis. 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