{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:15:25Z","timestamp":1756462525804},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"727","license":[{"start":{"date-parts":[[1986,5,1]],"date-time":"1986-05-01T00:00:00Z","timestamp":515289600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1986,5,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>The case is described of a 68 year old man who was immunosuppressed as a result of receiving chemotherapy for small cell lung cancer and who presented with severe right thigh pain. This proved to be due to clostridial myonecrosis with none of the classical clinical features of clostridial infection. This is believed to be the first reported case of spontaneous clostridial infection associated with etoposide administration.<\/jats:p>","DOI":"10.1136\/pgmj.62.727.403","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:58:16Z","timestamp":1230584296000},"page":"403-404","source":"Crossref","is-referenced-by-count":1,"title":["Clostridial myonecrosis in association with etoposide therapy presenting as severe thigh pain"],"prefix":"10.1093","volume":"62","author":[{"given":"D","family":"Smith","sequence":"first","affiliation":[{"name":"Cancer Research Campaign Department of Medical Oncology, Christie Hospital and Holt Radium Institute , Manchester M20 9BX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Harris","sequence":"additional","affiliation":[{"name":"Department of Pathology, Christie Hospital and Holt Radium Institute , Manchester M20 9BX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Thatcher","sequence":"additional","affiliation":[{"name":"Cancer Research Campaign Department of Medical Oncology, Christie Hospital and Holt Radium Institute , Manchester M20 9BX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1986,5,1]]},"reference":[{"key":"ref_1","author":"ACHTERRACH, W.; NIEDERLE, N.; HILGARD, P.","year":"1982","unstructured":"ACHTERRACH, W., NIEDERLE, N. & HILGARD, P. (1982)."},{"key":"ref_2","first-page":"542","article-title":"Non-traumatic clostridial myonecrosis","volume":"65","author":"GILBERT, D.N.","year":"1975","unstructured":"GILBERT, D.N. (1975). Non-traumatic clostridial myonecrosis. American Journal of Medicine, 65, 542.","journal-title":"American Journal of Medicine"},{"key":"ref_3","first-page":"1276","article-title":"Case Records ofthe Massachusetts General Hospital","volume":"301","author":"SCULLY, E.R.; GALDABINI, J.J.; McNEELY, B.U.","year":"1979","unstructured":"SCULLY, E.R., GALDABINI, J.J. & McNEELY, B.U. (1979). Case Records ofthe Massachusetts General Hospital. New England Journal of Medicine, 301, 1276.","journal-title":"New England Journal of Medicine"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/bjc.1985.197","article-title":"Three months treatment with chemotherapy and radiotherapy for small cell lung cancer","volume":"52","year":"1985","unstructured":"THATCHER, N., STOUT, R., SMITH, D.B.,,GROTTE, G., WINSON, M., BASSETT, H. & CARROLL, K.B. (1985). Three months treatment with chemotherapy and radiotherapy for small cell lung cancer. British Journal of Cancer, 52, 327.","journal-title":"British Journal of Cancer"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/1097-0142(197201)29:1<215::AID-CNCR2820290132>3.0.CO;2-C","article-title":"Clostridial septicaemia","volume":"29","author":"WYNNE, J.W.; ARMSTRONG, D.","year":"1972","unstructured":"WYNNE, J.W. & ARMSTRONG, D. (1972). Clostridial septicaemia. Cancer, 29, 215.","journal-title":"Cancer"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/62\/727\/403\/50157263\/postgradmedj-62-403.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/62\/727\/403\/50157263\/postgradmedj-62-403.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T11:42:44Z","timestamp":1683200564000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/62\/727\/403\/7042685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,5,1]]},"references-count":5,"journal-issue":{"issue":"727","published-online":{"date-parts":[[1986,5,1]]},"published-print":{"date-parts":[[1986,5,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.62.727.403","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1986,5]]},"published":{"date-parts":[[1986,5,1]]}}}